Microscopy imaging device with advanced imaging properties

Ghosh, Kunal; Burns, Laurie D.; El Gamal, Abbas; Schnitzer, Mark J.; Cocker, Eric; Ho, Tatt Wei

Microscopy imaging device with advanced imaging properties

Patent · 27 October 2020

OSTI ID:1771547

Ghosh, Kunal; Burns, Laurie D.; El Gamal, Abbas; Schnitzer, Mark J.; Cocker, Eric; Ho, Tatt Wei

Systems, methods and devices are implemented for microscope imaging solutions. One embodiment of the present disclosure is directed toward an epifluorescence microscope. The microscope includes an image capture circuit including an array of optical sensor. An optical arrangement is configured to direct excitation light of less than about 1 mW to a target object in a field of view of that is at least 0.5 mm² and to direct epi-fluorescence emission caused by the excitation light to the array of optical sensors. The optical arrangement and array of optical sensors are each sufficiently close to the target object to provide at least 2.5 μm resolution for an image of the field of view.

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Research Organization:: Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: AC52-07NA27344

Assignee:: The Board of Trustees of the Leland Stanford Junior University (Stanford, CA)

Patent Number(s):: 10,813,552

Application Number:: 15/444,049

OSTI ID:: 1771547

Country of Publication:: United States

Language:: English

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