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Title: Bis-polymer lipid-peptide conjugates and nanoparticles thereof

Patent ·
OSTI ID:1771519

The present invention provides bis-polymer lipid-peptide conjugates containing a hydrophobic block and headgroup containing a helical peptide and two polymer blocks. The conjugates can self-assemble to form helix bundle subunits, which in turn assemble to provide micellar nanocarriers for drug cargos and other agents. Particles containing the conjugates and methods for forming the particles are also disclosed.

Research Organization:
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC02-05CH11231
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Number(s):
10,806,702
Application Number:
15/961,111
OSTI ID:
1771519
Resource Relation:
Patent File Date: 04/24/2018
Country of Publication:
United States
Language:
English

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