Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection
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journal
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May 2008 |
Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus
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April 2013 |
Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies
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March 2014 |
Cooperation of B Cell Lineages in Induction of HIV-1-Broadly Neutralizing Antibodies
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journal
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July 2014 |
Viral variants that initiate and drive maturation of V1V2-directed HIV-1 broadly neutralizing antibodies
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journal
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October 2015 |
Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody
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April 2016 |
Staged induction of HIV-1 glycan–dependent broadly neutralizing antibodies
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March 2017 |
HIV Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage
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November 2017 |
Envelope residue 375 substitutions in simian–human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaques
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May 2016 |
HIV-1 Vaccines Based on Antibody Identification, B Cell Ontogeny, and Epitope Structure
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journal
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May 2018 |
Recent progress in broadly neutralizing antibodies to HIV
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October 2018 |
Cardiolipin Polyspecific Autoreactivity in Two Broadly Neutralizing HIV-1 Antibodies
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June 2005 |
Structural Survey of Broadly Neutralizing Antibodies Targeting the HIV-1 Env Trimer Delineates Epitope Categories and Characteristics of Recognition
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January 2019 |
Error thresholds and the constraints to RNA virus evolution
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journal
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December 2003 |
Constraints on HIV-1 Diversity from Protein Structure
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journal
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September 2010 |
Experimental Estimation of the Effects of All Amino-Acid Mutations to HIV’s Envelope Protein on Viral Replication in Cell Culture
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December 2016 |
The antigenic structure of the HIV gp120 envelope glycoprotein
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June 1998 |
Antibody neutralization and escape by HIV-1
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March 2003 |
Identification and characterization of conserved and variable regions in the envelope gene of HTLV-III/LAV, the retrovirus of AIDS
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June 1986 |
HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites
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journal
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December 2002 |
Structure and Diversity of the Rhesus Macaque Immunoglobulin Loci through Multiple De Novo Genome Assemblies
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journal
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October 2017 |
Multiple Pathways of Escape from HIV Broadly Cross-Neutralizing V2-Dependent Antibodies
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journal
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February 2013 |
Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations
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journal
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November 2017 |
Magnitude and Kinetics of CD8+ T Cell Activation during Hyperacute HIV Infection Impact Viral Set Point
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journal
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September 2015 |
Prospective Study of Acute HIV-1 Infection in Adults in East Africa and Thailand
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journal
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June 2016 |
Tiered Categorization of a Diverse Panel of HIV-1 Env Pseudoviruses for Assessment of Neutralizing Antibodies
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November 2009 |
Global Panel of HIV-1 Env Reference Strains for Standardized Assessments of Vaccine-Elicited Neutralizing Antibodies
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journal
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December 2013 |
Prevalence of broadly neutralizing antibody responses during chronic HIV-1 infection
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journal
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January 2014 |
Human Immunodeficiency Virus Type 2 (HIV-2)/HIV-1 Envelope Chimeras Detect High Titers of Broadly Reactive HIV-1 V3-Specific Antibodies in Human Plasma
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journal
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November 2008 |
Effect of the cytoplasmic domain on antigenic characteristics of HIV-1 envelope glycoprotein
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journal
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June 2015 |
Broadly Neutralizing Antibody Responses in a Large Longitudinal Sub-Saharan HIV Primary Infection Cohort
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journal
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January 2016 |
Development of broadly neutralizing antibodies in HIV-1 infected elite neutralizers
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journal
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September 2018 |
Neutralization Properties of Simian Immunodeficiency Viruses Infecting Chimpanzees and Gorillas
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journal
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April 2015 |
The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection
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journal
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June 2009 |
Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection
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journal
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June 2009 |
Early Low-Titer Neutralizing Antibodies Impede HIV-1 Replication and Select for Virus Escape
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journal
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May 2012 |
A Novel Antiviral Intervention Results in More Accurate Assessment of Human Immunodeficiency Virus Type 1 Replication Dynamics and T-Cell Decay In Vivo
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journal
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April 2003 |
Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection
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journal
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January 1995 |
Viral dynamics in human immunodeficiency virus type 1 infection
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journal
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January 1995 |
Antiviral pressure exerted by HIV-l-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus
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journal
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February 1997 |
Longitudinal Antigenic Sequences and Sites from Intra-Host Evolution (LASSIE) Identifies Immune-Selected HIV Variants
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journal
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October 2015 |
Completeness of HIV-1 Envelope Glycan Shield at Transmission Determines Neutralization Breadth
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journal
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October 2018 |
Structure, Replication, and Recombination of Retrovirus Genomes: Some Unifying Hypotheses
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January 1979 |
HIV Evolution in Early Infection: Selection Pressures, Patterns of Insertion and Deletion, and the Impact of APOBEC
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journal
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May 2009 |
New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional Potency
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journal
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October 2015 |
Targeted selection of HIV-specific antibody mutations by engineering B cell maturation
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journal
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December 2019 |
Identification of Common Features in Prototype Broadly Neutralizing Antibodies to HIV Envelope V2 Apex to Facilitate Vaccine Design
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journal
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November 2015 |
Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design
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journal
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December 2015 |
Structure of Super-Potent Antibody CAP256-VRC26.25 in Complex with HIV-1 Envelope Reveals a Combined Mode of Trimer-Apex Recognition
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journal
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April 2020 |
Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding
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journal
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July 2011 |
Functional Relevance of Improbable Antibody Mutations for HIV Broadly Neutralizing Antibody Development
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journal
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June 2018 |
Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies
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journal
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August 2013 |
Production of individualized V gene databases reveals high levels of immunoglobulin genetic diversity
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journal
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December 2016 |
Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design
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journal
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June 2018 |
Delineating Antibody Recognition in Polyclonal Sera from Patterns of HIV-1 Isolate Neutralization
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journal
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May 2013 |
HIV-1 Neutralizing Antibody Signatures and Application to Epitope-Targeted Vaccine Design
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journal
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January 2019 |
Rapid development of glycan-specific, broad, and potent anti-HIV-1 gp120 neutralizing antibodies in an R5 SIV/HIV chimeric virus infected macaque
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journal
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November 2011 |
Development of Broadly Neutralizing Antibodies and Their Mapping by Monomeric gp120 in Human Immunodeficiency Virus Type 1-Infected Humans and Simian-Human Immunodeficiency Virus SHIV SF162P3N -Infected Macaques
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journal
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February 2016 |
Development of broad neutralization activity in simian/human immunodeficiency virus-infected rhesus macaques after long-term infection
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journal
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January 2018 |
Development of Antibodies with Broad Neutralization Specificities against HIV-1 after Long Term SHIV Infection in Macaques
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journal
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January 2020 |
Induction of Antibodies in Guinea Pigs and Rhesus Monkeys against the Human Immunodeficiency Virus Type 1 Envelope: Neutralization of Nonpathogenic and Pathogenic Primary Isolate Simian/Human Immunodeficiency Virus Strains
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journal
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January 2000 |
Analysis of HIV-1 subtype B third variable region peptide motifs for induction of neutralizing antibodies against HIV-1 primary isolates
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journal
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February 2006 |
Polyvalent HIV-1 Env vaccine formulations delivered by the DNA priming plus protein boosting approach are effective in generating neutralizing antibodies against primary human immunodeficiency virus type 1 isolates from subtypes A, B, C, D and E
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journal
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June 2006 |
Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches
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journal
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June 2017 |
Vaccine Induction of Heterologous Tier 2 HIV-1 Neutralizing Antibodies in Animal Models
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journal
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December 2017 |
Immunogenicity in Rabbits of HIV-1 SOSIP Trimers from Clades A, B, and C, Given Individually, Sequentially, or in Combination
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journal
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January 2018 |
Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization
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journal
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July 2019 |
Env Exceptionalism: Why Are HIV-1 Env Glycoproteins Atypical Immunogens?
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journal
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April 2020 |
A broadly neutralizing macaque monoclonal antibody against the HIV-1 V3-Glycan patch
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journal
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October 2020 |
Multiple roles for HIV broadly neutralizing antibodies
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journal
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October 2019 |
Vaccines and Broadly Neutralizing Antibodies for HIV-1 Prevention
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journal
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April 2020 |
Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques
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journal
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May 2019 |
A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses
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journal
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October 2019 |
A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield
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journal
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October 2011 |
A Prominent Site of Antibody Vulnerability on HIV Envelope Incorporates a Motif Associated with CCR5 Binding and Its Camouflaging Glycans
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journal
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July 2016 |
Broadly Neutralizing Antibody PGT121 Allosterically Modulates CD4 Binding via Recognition of the HIV-1 gp120 V3 Base and Multiple Surrounding Glycans
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journal
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May 2013 |
B-cell–lineage immunogen design in vaccine development with HIV-1 as a case study
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journal
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May 2012 |
The Neutralizing Antibody Response to the HIV-1 Env Protein
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journal
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April 2018 |
Optimization and validation of the TZM-bl assay for standardized assessments of neutralizing antibodies against HIV-1
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journal
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July 2014 |
Difficult-to-neutralize global HIV-1 isolates are neutralized by antibodies targeting open envelope conformations
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journal
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July 2019 |
Potent and broad HIV-neutralizing antibodies in memory B cells and plasma
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journal
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January 2017 |
Antigenicity and Immunogenicity of RV144 Vaccine AIDSVAX Clade E Envelope Immunogen Is Enhanced by a gp120 N-Terminal Deletion
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journal
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November 2012 |
Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide
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journal
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March 2017 |
High-throughput isolation of immunoglobulin genes from single human B cells and expression as monoclonal antibodies
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journal
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June 2009 |
Analysis of a Clonal Lineage of HIV-1 Envelope V2/V3 Conformational Epitope-Specific Broadly Neutralizing Antibodies and Their Inferred Unmutated Common Ancestors
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journal
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July 2011 |
IDLV-HIV-1 Env vaccination in non-human primates induces affinity maturation of antigen-specific memory B cells
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journal
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September 2018 |
HIV-1 gp120 Vaccine Induces Affinity Maturation in both New and Persistent Antibody Clonal Lineages
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journal
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May 2012 |
Antibody Light-Chain-Restricted Recognition of the Site of Immune Pressure in the RV144 HIV-1 Vaccine Trial Is Phylogenetically Conserved
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journal
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December 2014 |
Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1
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journal
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July 2010 |
Evaluating Neutralizing Antibodies Against HIV, SIV, and SHIV in Luciferase Reporter Gene Assays
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journal
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December 2004 |
Bacteria in cancer therapy: a novel experimental strategy
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journal
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January 2010 |
Optimization and qualification of an 8-color intracellular cytokine staining assay for quantifying T cell responses in rhesus macaques for pre-clinical vaccine studies
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journal
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December 2012 |
Isolation of human monoclonal antibodies from peripheral blood B cells
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journal
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September 2013 |
High throughput HIV-1 microneutralization assay
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journal
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September 2013 |
Rapid generation of fully human monoclonal antibodies specific to a vaccinating antigen
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journal
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February 2009 |
Base-Calling of Automated Sequencer Traces Using Phred. I. Accuracy Assessment
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journal
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March 1998 |
SoDA: implementation of a 3D alignment algorithm for inference of antigen receptor recombinations
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journal
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December 2005 |
Reconstructing a B-Cell Clonal Lineage. II. Mutation, Selection, and Affinity Maturation
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journal
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April 2014 |
Initiation of immune tolerance–controlled HIV gp41 neutralizing B cell lineages
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journal
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April 2016 |
Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning
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journal
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January 2008 |
Targeted Isolation of Antibodies Directed against Major Sites of SIV Env Vulnerability
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journal
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April 2016 |
Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual
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journal
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March 2019 |
SONAR: A High-Throughput Pipeline for Inferring Antibody Ontogenies from Longitudinal Sequencing of B Cell Transcripts
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journal
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September 2016 |
Hierarchical Grouping to Optimize an Objective Function
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journal
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March 1963 |
A Next-Generation Cleaved, Soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, Expresses Multiple Epitopes for Broadly Neutralizing but Not Non-Neutralizing Antibodies
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journal
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September 2013 |
Structure and immune recognition of trimeric pre-fusion HIV-1 Env
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journal
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October 2014 |
Surface-Matrix Screening Identifies Semi-specific Interactions that Improve Potency of a Near Pan-reactive HIV-1-Neutralizing Antibody
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journal
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February 2018 |
Automated molecular microscopy: The new Leginon system
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July 2005 |
DoG Picker and TiltPicker: Software tools to facilitate particle selection in single particle electron microscopy
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journal
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May 2009 |
Appion: An integrated, database-driven pipeline to facilitate EM image processing
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journal
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April 2009 |
MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy
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journal
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February 2017 |
CTFFIND4: Fast and accurate defocus estimation from electron micrographs
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journal
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November 2015 |
Gctf: Real-time CTF determination and correction
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journal
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January 2016 |
RELION: Implementation of a Bayesian approach to cryo-EM structure determination
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journal
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December 2012 |
cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination
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February 2017 |
Improvement of antibody functionality by structure-guided paratope engraftment
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February 2019 |
Recent developments in the PHENIX software for automated crystallographic structure determination
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November 2003 |
Coot model-building tools for molecular graphics
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journal
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November 2004 |
MOLPROBITY: structure validation and all-atom contact analysis for nucleic acids and their complexes
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journal
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July 2004 |
EMRinger: side chain–directed model and map validation for 3D cryo-electron microscopy
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August 2015 |
Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains
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June 2014 |
XDS
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journal
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January 2010 |
Phaser crystallographic software
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journal
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July 2007 |
Features and development of Coot
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March 2010 |
EMAN2: An extensible image processing suite for electron microscopy
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journal
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January 2007 |
Adaptive changes in HIV-1 subtype C proteins during early infection are driven by changes in HLA-associated immune pressure
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journal
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January 2010 |
The Chimpanzee SIV Envelope Trimer: Structure and Deployment as an HIV Vaccine Template
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journal
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May 2019 |
Identification of a New Quaternary Neutralizing Epitope on Human Immunodeficiency Virus Type 1 Virus Particles
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journal
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April 2005 |
Type-Specific Epitopes Targeted by Monoclonal Antibodies with Exceptionally Potent Neutralizing Activities for Selected Strains of Human Immunodeficiency Virus Type 1 Map to a Common Region of the V2 Domain of gp120 and Differ Only at Single Positions from the Clade B Consensus Sequence
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journal
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November 2006 |
Structural Analysis of Human and Macaque mAbs 2909 and 2.5B: Implications for the Configuration of the Quaternary Neutralizing Epitope of HIV-1 gp120
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journal
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May 2011 |
Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation
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journal
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April 2017 |