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Title: Molecular rheostat for cofactor balance

Patent ·
OSTI ID:1735203
; ;

The disclosure provides a metabolic pathway for producing a metabolite, the metabolic pathway having a co-factor regulatory system for cofactor utilization in the metabolic pathway.

Research Organization:
Univ. of California, Oakland, CA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AR0000556
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Number(s):
10,760,103
Application Number:
16/342,849
OSTI ID:
1735203
Resource Relation:
Patent File Date: 10/18/2017
Country of Publication:
United States
Language:
English

References (6)

l -Lysine production independent of the oxidative pentose phosphate pathway by Corynebacterium glutamicum with the Streptococcus mutans gapN gene journal September 2016
Metabolic engineering of Corynebacterium glutamicum for increasing the production of l -ornithine by increasing NADPH availability journal October 2013
The Rhodococcus opacus TadD protein mediates triacylglycerol metabolism by regulating intracellular NAD(P)H pools journal January 2013
Genes and uses for plant improvement patent-application April 2006
Improving poly-3-hydroxybutyrate production in Escherichia coli by combining the increase in the NADPH pool and acetyl-CoA availability journal February 2014
Two Glyceraldehyde-3-phosphate Dehydrogenases with Opposite Physiological Roles in a Nonphotosynthetic Bacterium journal May 2000

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