RCSB Protein Data Bank: powerful new tools for exploring 3D structures of biological macromolecules for basic and applied research and education in fundamental biology, biomedicine, biotechnology, bioengineering and energy sciences

Burley, Stephen K.; Bhikadiya, Charmi; Bi, Chunxiao; Bittrich, Sebastian; Chen, Li; Crichlow, Gregg V.; Christie, Cole H.; Dalenberg, Kenneth; Di Costanzo, Luigi; Duarte, Jose M.; Dutta, Shuchismita; Feng, Zukang; Ganesan, Sai; Goodsell, David S.; Ghosh, Sutapa; Green, Rachel Kramer; Guranović, Vladimir; Guzenko, Dmytro; Hudson, Brian P.; Lawson, Catherine L.; Liang, Yuhe; Lowe, Robert; Namkoong, Harry; Peisach, Ezra; Persikova, Irina; Randle, Chris; Rose, Alexander; Rose, Yana; Sali, Andrej; Segura, Joan; Sekharan, Monica; Shao, Chenghua; Tao, Yi-Ping; Voigt, Maria; Westbrook, John D.; Young, Jasmine Y.; Zardecki, Christine; Zhuravleva, Marina

doi:10.1093/nar/gkaa1038

RCSB Protein Data Bank: powerful new tools for exploring 3D structures of biological macromolecules for basic and applied research and education in fundamental biology, biomedicine, biotechnology, bioengineering and energy sciences

Journal Article · Wed Nov 18 23:00:00 EST 2020 · Nucleic Acids Research

DOI:https://doi.org/10.1093/nar/gkaa1038· OSTI ID:1734440

^[1]; Bhikadiya, Charmi ^[2]; Bi, Chunxiao ^[3]; ^[3]; Chen, Li ^[2]; ^[2]; Christie, Cole H. ^[3]; Dalenberg, Kenneth ^[2]; Di Costanzo, Luigi ^[2]; ^[3]; Dutta, Shuchismita ^[4]; ^[2]; Ganesan, Sai ^[5]; ^[6]; Ghosh, Sutapa ^[2]; Green, Rachel Kramer ^[2]; Guranović, Vladimir ^[2]; Guzenko, Dmytro ^[3]; ^[2]; Lawson, Catherine L. ^[2] more »

Research Collaboratory for Structural Bioinformatics Protein Data Bank; Rutgers; The State University of New Jersey; Piscataway; NJ 08854; USA; Institute for Quantitative Biomedicine; Rutgers; The State University of New Jersey; Piscataway; NJ 08854; USA; Cancer Institute of New Jersey; Rutgers; The State University of New Jersey; New Brunswick; NJ 08901; USA; Research Collaboratory for Structural Bioinformatics Protein Data Bank; San Diego Supercomputer Center; University of California; La Jolla; CA 92093; USA; Department of Chemistry and Chemical Biology; Rutgers; The State University of New Jersey; Piscataway; NJ 08854; USA
Research Collaboratory for Structural Bioinformatics Protein Data Bank, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA, Institute for Quantitative Biomedicine, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
Research Collaboratory for Structural Bioinformatics Protein Data Bank, San Diego Supercomputer Center, University of California, La Jolla, CA 92093, USA
Research Collaboratory for Structural Bioinformatics Protein Data Bank, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA, Institute for Quantitative Biomedicine, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA, Cancer Institute of New Jersey, Rutgers, The State University of New Jersey, New Brunswick, NJ 08901, USA
Research Collaboratory for Structural Bioinformatics Protein Data Bank, Department of Biotherapeutic Sciences, University of California, San Francisco, San Francisco, CA 94158, USA
Research Collaboratory for Structural Bioinformatics Protein Data Bank, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA, Institute for Quantitative Biomedicine, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA, Center for Computational Structural Biology, The Scripps Research Institute, La Jolla, CA 92037, USA

Abstract

The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB), the US data center for the global PDB archive and a founding member of the Worldwide Protein Data Bank partnership, serves tens of thousands of data depositors in the Americas and Oceania and makes 3D macromolecular structure data available at no charge and without restrictions to millions of RCSB.org users around the world, including >660 000 educators, students and members of the curious public using PDB101.RCSB.org. PDB data depositors include structural biologists using macromolecular crystallography, nuclear magnetic resonance spectroscopy, 3D electron microscopy and micro-electron diffraction. PDB data consumers accessing our web portals include researchers, educators and students studying fundamental biology, biomedicine, biotechnology, bioengineering and energy sciences. During the past 2 years, the research-focused RCSB PDB web portal (RCSB.org) has undergone a complete redesign, enabling improved searching with full Boolean operator logic and more facile access to PDB data integrated with >40 external biodata resources. New features and resources are described in detail using examples that showcase recently released structures of SARS-CoV-2 proteins and host cell proteins relevant to understanding and addressing the COVID-19 global pandemic.

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Sponsoring Organization:: USDOE

Grant/Contract Number:: SC0019749

OSTI ID:: 1734440

Alternate ID(s):: OSTI ID: 1853382

Journal Information:: Nucleic Acids Research, Journal Name: Nucleic Acids Research Journal Issue: D1 Vol. 49; ISSN 0305-1048

Publisher:: Oxford University PressCopyright Statement

Country of Publication:: United Kingdom

Language:: English

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RCSB Protein Data Bank: biological macromolecular structures enabling research and education in fundamental biology, biomedicine, biotechnology and energy

Journal Article · Wed Oct 24 00:00:00 EDT 2018 · Nucleic Acids Research · OSTI ID:1600525

RCSB Protein Data Bank: powerful new tools for exploring 3D structures of biological macromolecules for basic and applied research and education in fundamental biology, biomedicine, biotechnology, bioengineering and energy sciences

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