Biological effects of inhaled 238PuO2 in beagles
- BATTELLE (PACIFIC NW LAB)
- Pacific Northwest National Laboratory
Beagle dogs exposed to 238PuO2 aerosols were observed throughout life to determine tissues at risk and dose-effect relationships. Although lungs accumulated a higher average radiation dose than skeleton, more deaths were due to bone tumors than lung tumors. The 50-year estimates for humans was an order of magnitude lower than doses at which increased incidence of neoplasia was observed in these dogs, whereas the projected doses to humans for deterministic effects were similar to those seen in the beagles.
- Research Organization:
- Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- AC05-76RL01830
- OSTI ID:
- 1701733
- Report Number(s):
- PNWD-SA-5287
- Journal Information:
- Radiation Research, Journal Name: Radiation Research Journal Issue: 4 Vol. 148; ISSN 0033-7587
- Country of Publication:
- United States
- Language:
- English
Similar Records
Primary bone neoplasms in beagle dogs exposed by inhalation to aerosols of plutonium-238 dioxide
The Association of Inbreeding With Lung Fibrosis Incidence in Beagle Dogs That Inhaled 238PuO2 or 239PuO2.
Toxicity of inhaled plutonium dioxide in beagle dogs
Journal Article
·
Thu Oct 01 00:00:00 EDT 1981
· J. Natl. Cancer Inst.; (United States)
·
OSTI ID:5462772
The Association of Inbreeding With Lung Fibrosis Incidence in Beagle Dogs That Inhaled 238PuO2 or 239PuO2.
Journal Article
·
Mon Sep 12 00:00:00 EDT 2011
· Radiation Research
·
OSTI ID:1033068
Toxicity of inhaled plutonium dioxide in beagle dogs
Journal Article
·
Thu Feb 29 23:00:00 EST 1996
· Radiation Research
·
OSTI ID:387377