Design, synthesis, and structure-activity relationships of novel 4,7,12,12a-tetrahydro-5H-thieno[3′,2′:3,4]pyrido[1,2-b]isoquinoline and 5,8,12,12a-tetrahydro-6H-thieno[2′,3′:4,5]pyrido[2,1-a]isoquinoline derivatives as cellular activators of adenosine 5′-monophosphate-activated protein kinase (AMPK)

Gu, Zhanni; Wu, Lingyan; Duan, Yanan; Wang, Jiang; Zhou, Shengbin; Li, Jingya; Chen, Kaixian; Li, Jia; Liu, Hong

doi:10.1016/j.bmc.2018.02.052

Design, synthesis, and structure-activity relationships of novel 4,7,12,12a-tetrahydro-5H-thieno[3′,2′:3,4]pyrido[1,2-b]isoquinoline and 5,8,12,12a-tetrahydro-6H-thieno[2′,3′:4,5]pyrido[2,1-a]isoquinoline derivatives as cellular activators of adenosine 5′-monophosphate-activated protein kinase (AMPK)

Journal Article · Tue May 01 00:00:00 EDT 2018 · Bioorganic and Medicinal Chemistry

DOI:https://doi.org/10.1016/j.bmc.2018.02.052· OSTI ID:1693976

Gu, Zhanni; Wu, Lingyan; Duan, Yanan; Wang, Jiang; Zhou, Shengbin; Li, Jingya; Chen, Kaixian; Li, Jia; Liu, Hong

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View Accepted Manuscript (Publisher)

Sponsoring Organization:: USDOE Office of Electricity (OE), Advanced Grid Research & Development. Power Systems Engineering Research

OSTI ID:: 1693976

Journal Information:: Bioorganic and Medicinal Chemistry, Journal Name: Bioorganic and Medicinal Chemistry Journal Issue: 8 Vol. 26; ISSN 0968-0896

Publisher:: ElsevierCopyright Statement

Country of Publication:: United Kingdom

Language:: English

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