Bacterial lipids: Metabolism and membrane homeostasis
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journal
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July 2013 |
A triclosan-resistant bacterial enzyme
|
journal
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July 2000 |
Characterization of Streptococcus pneumoniae enoyl-(acyl-carrier protein) reductase (FabK)
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journal
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March 2003 |
Crystal structure of enoyl-acyl carrier protein reductase (FabK) from Streptococcus pneumoniae reveals the binding mode of an inhibitor
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journal
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April 2008 |
Structural characterization of Porphyromonas gingivalis enoyl-ACP reductase II (FabK)
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January 2018 |
Short-chain dehydrogenases/reductases (SDR): the 2002 update
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journal
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February 2003 |
The Structural Biology of type ii Fatty acid Biosynthesis
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journal
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June 2005 |
Enoyl-acyl-carrier-protein reductase and Mycobacterium tuberculosis InhA do not conserve the Tyr-Xaa-Xaa-Xaa-Lys motif in mammalian 11 β- and 17 β-hydroxysteroid dehydrogenases and Drosophila alcohol dehydrogenase
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journal
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August 1995 |
Roles of Tyrosine 158 and Lysine 165 in the Catalytic Mechanism of InhA, the Enoyl-ACP Reductase from Mycobacterium tuberculosis †
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journal
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October 1999 |
The Enoyl-[acyl-carrier-protein] Reductases FabI and FabL from Bacillus subtilis
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journal
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September 2000 |
Crystal Structures of Enoyl-ACP Reductases I (FabI) and III (FabL) from B. subtilis
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journal
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February 2011 |
Vibrio cholerae FabV Defines a New Class of Enoyl-Acyl Carrier Protein Reductase
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journal
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November 2007 |
Triclosan Resistance of Pseudomonas aeruginosa PAO1 Is Due to FabV, a Triclosan-Resistant Enoyl-Acyl Carrier Protein Reductase
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journal
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February 2010 |
Structure of the Yersinia pestis FabV Enoyl-ACP Reductase and Its Interaction with Two 2-Pyridone Inhibitors
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journal
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January 2012 |
Enoyl-Acyl Carrier Protein Reductase ( fabI ) Plays a Determinant Role in Completing Cycles of Fatty Acid Elongation in Escherichia coli
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journal
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November 1995 |
Resistance Mechanisms and the Future of Bacterial Enoyl-Acyl Carrier Protein Reductase (FabI) Antibiotics
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journal
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March 2016 |
Bacterial fatty acid metabolism in modern antibiotic discovery
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journal
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November 2017 |
In vitro activity (MICs and rate of kill) of AFN-1252, a novel FabI inhibitor, in the presence of serum and in combination with other antibiotics
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journal
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February 2013 |
Mode of Action, In Vitro Activity, and In Vivo Efficacy of AFN-1252, a Selective Antistaphylococcal FabI Inhibitor
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journal
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September 2012 |
Efficacy and Safety of AFN-1252, the First Staphylococcus-Specific Antibacterial Agent, in the Treatment of Acute Bacterial Skin and Skin Structure Infections, Including Those in Patients with Significant Comorbidities
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journal
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March 2016 |
Bone and Joint Tissue Penetration of the Staphylococcus -Selective Antibiotic Afabicin in Patients Undergoing Elective Hip Replacement Surgery
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journal
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March 2019 |
Effects of Antibiotics on Human Microbiota and Subsequent Disease
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journal
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September 2014 |
Prolonged Impact of Antibiotics on Intestinal Microbial Ecology and Susceptibility to Enteric Salmonella Infection
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journal
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April 2009 |
A Pathogen-Selective Antibiotic Minimizes Disturbance to the Microbiome
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journal
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July 2016 |
What is the Healthy Gut Microbiota Composition? A Changing Ecosystem across Age, Environment, Diet, and Diseases
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journal
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January 2019 |
Kinetic and Structural Characteristics of the Inhibition of Enoyl (Acyl Carrier Protein) Reductase by Triclosan ‡
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journal
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September 1999 |
Staphylococcus aureus FabI: Inhibition, Substrate Recognition, and Potential Implications for In Vivo Essentiality
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journal
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May 2012 |
Crystal Structure of the Mycobacterium tuberculosis Enoyl-ACP Reductase, InhA, in Complex with NAD + and a C16 Fatty Acyl Substrate
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journal
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May 1999 |
Type II Fatty Acid Synthesis Is Essential for the Replication of Chlamydia trachomatis
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journal
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August 2014 |
Design, Synthesis, and Biological and Crystallographic Evaluation of Novel Inhibitors of Plasmodium falciparum Enoyl-ACP-reductase ( Pf FabI)
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journal
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September 2013 |
Microbiome and metabolic disease: revisiting the bacterial phylum Bacteroidetes
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journal
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November 2016 |
AFN-1252, a FabI Inhibitor, Demonstrates a Staphylococcus-Specific Spectrum of Activity
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journal
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August 2009 |
Resistance to AFN-1252 Arises from Missense Mutations in Staphylococcus aureus Enoyl-acyl Carrier Protein Reductase (FabI)
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journal
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December 2013 |
Inhibition of the Staphylococcus aureusNADPH-dependent Enoyl-Acyl Carrier Protein Reductase by Triclosan and Hexachlorophene
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journal
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February 2000 |
Mechanism of Triclosan Inhibition of Bacterial Fatty Acid Synthesis
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journal
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April 1999 |
Crystallographic insights into the structure–activity relationships of diazaborine enoyl-ACP reductase inhibitors
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journal
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November 2015 |
A New Mechanism for Anaerobic Unsaturated Fatty Acid Formation in Streptococcus pneumoniae
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journal
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September 2002 |
Structural insights into the dimer-tetramer transition of FabI from Bacillus anthracis
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journal
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November 2017 |
Dimeric and tetrameric forms of enoyl-acyl carrier protein reductase from Bacillus cereus
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journal
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October 2010 |
Structural insights into Staphylococcus aureus enoyl-ACP reductase (FabI), in complex with NADP and triclosan: Crystal Structure of Enoyl-ACP Reductase from S. Aureus
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journal
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August 2009 |
Common themes in redox chemistry emerge from the X-ray structure of oilseed rape (Brassica napus) enoyl acyl carrier protein reductase
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journal
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September 1995 |
Structural Elucidation of the Specificity of the Antibacterial Agent Triclosan for Malarial Enoyl Acyl Carrier Protein Reductase
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journal
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April 2002 |
A Slow, Tight Binding Inhibitor of InhA, the Enoyl-Acyl Carrier Protein Reductase from Mycobacterium tuberculosis
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journal
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March 2010 |
Structural Basis for the Variation in Triclosan Affinity to Enoyl Reductases
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journal
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October 2004 |
The refined three-dimensional structure of 3α,20β-hydroxysteroid dehydrogenase and possible roles of the residues conserved in short-chain dehydrogenases
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journal
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July 1994 |
Crystal Structures of the Binary and Ternary Complexes of 7α-Hydroxysteroid Dehydrogenase from Escherichia coli ,
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journal
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January 1996 |
The α-helix dipole and the properties of proteins
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journal
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June 1978 |
Studies of Toxoplasma gondii and Plasmodium falciparum enoyl acyl carrier protein reductase and implications for the development of antiparasitic agents
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journal
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February 2007 |
Molecular basis for triclosan activity involves a flipping loop in the active site
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journal
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January 1999 |
Crystal structure and function of the isoniazid target of Mycobacterium tuberculosis
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journal
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March 1995 |
Structural and Enzymatic Analyses Reveal the Binding Mode of a Novel Series of Francisella tularensis Enoyl Reductase (FabI) Inhibitors
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journal
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June 2012 |
An Ordered Water Channel in Staphylococcus aureus FabI: Unraveling the Mechanism of Substrate Recognition and Reduction
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journal
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March 2015 |
Planar Stacking Interactions of Arginine and Aromatic Side-Chains in Proteins
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journal
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January 1994 |
Modification of the NADH of the Isoniazid Target (InhA) from Mycobacterium tuberculosis
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journal
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January 1998 |
The effects of antibiotics on the microbiome throughout development and alternative approaches for therapeutic modulation
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journal
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April 2016 |
phangorn: phylogenetic analysis in R
|
journal
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December 2010 |
DECIPHER: harnessing local sequence context to improve protein multiple sequence alignment
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journal
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October 2015 |
An Improved General Amino Acid Replacement Matrix
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journal
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April 2008 |
ggtree : an r package for visualization and annotation of phylogenetic trees with their covariates and other associated data
|
journal
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September 2016 |
Fatty acid activation and utilization by Alistipes finegoldii , a representative Bacteroidetes resident of the human gut microbiome
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journal
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January 2020 |
Metabolic basis for the differential susceptibility of Gram-positive pathogens to fatty acid synthesis inhibitors
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journal
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August 2011 |
A Missense Mutation in the fabB (β-Ketoacyl-Acyl Carrier Protein Synthase I) Gene Confers Thiolactomycin Resistance to Escherichia coli
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journal
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May 2002 |
Overview of Current Methods in Sedimentation Velocity and Sedimentation Equilibrium Analytical Ultracentrifugation
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journal
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February 2013 |
Size-Distribution Analysis of Macromolecules by Sedimentation Velocity Ultracentrifugation and Lamm Equation Modeling
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journal
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March 2000 |
A Multilaboratory Comparison of Calibration Accuracy and the Performance of External References in Analytical Ultracentrifugation
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journal
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May 2015 |
Activation of Exogenous Fatty Acids to Acyl-Acyl Carrier Protein Cannot Bypass FabI Inhibition in Neisseria
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journal
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January 2016 |
[20] Processing of X-ray diffraction data collected in oscillation mode
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book
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January 1997 |
Solving structures of protein complexes by molecular replacement with Phaser
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journal
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December 2006 |
XDS
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journal
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January 2010 |
Direct incorporation of experimental phase information in model refinement
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journal
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November 2004 |
Coot model-building tools for molecular graphics
|
journal
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November 2004 |
The crystal structure of the Yersinia pestis iron chaperone YiuA reveals a basic triad binding motif for the chelated metal
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journal
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October 2017 |
Towards a new tuberculosis drug: pyridomycin – nature's isoniazid
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journal
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September 2012 |
Sequences of the envM gene and of two mutated alleles in Escherichia coli
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journal
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October 1992 |
Acyl-Phosphates Initiate Membrane Phospholipid Synthesis in Gram-Positive Pathogens
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journal
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September 2006 |