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Title: A Nanoscale Metal-Organic Framework to Mediate Photodynamic Therapy and Deliver CpG Oligodeoxynucleotides to Enhance Antigen Presentation and Cancer Immunotherapy

Journal Article · · Angew. Chem.-Ger. Edit.

Research Organization:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Organization:
NCINIH
OSTI ID:
1660997
Journal Information:
Angew. Chem.-Ger. Edit., Vol. 59, Issue (3) ; 01, 2020
Country of Publication:
United States
Language:
ENGLISH

References (33)

One-Pot Synthesis of Protein-Embedded Metal–Organic Frameworks with Enhanced Biological Activities journal September 2014
MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer journal November 2014
Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer journal June 2012
Structure-based programming of lymph-node targeting in molecular vaccines journal February 2014
Photodynamic therapy and anti-tumour immunity journal July 2006
Combining immunotherapy and targeted therapies in cancer treatment journal March 2012
Oligonucleotide-Modified Gold Nanoparticles for Intracellular Gene Regulation journal May 2006
Nanoscale Metal–Organic Framework for Highly Effective Photodynamic Therapy of Resistant Head and Neck Cancer journal November 2014
Cancer immunotherapy comes of age journal December 2011
One-pot Synthesis of Metal–Organic Frameworks with Encapsulated Target Molecules and Their Applications for Controlled Drug Delivery journal January 2016
Nanoscale Metal–Organic Framework Overcomes Hypoxia for Photodynamic Therapy Primed Cancer Immunotherapy journal April 2018
Nucleic Acid–Metal Organic Framework (MOF) Nanoparticle Conjugates journal May 2014
Immunogenic cell death in cancer and infectious disease journal October 2016
Nanoscale metal–organic frameworks for phototherapy of cancer journal January 2019
Oncology Meets Immunology: The Cancer-Immunity Cycle journal July 2013
Albumin/vaccine nanocomplexes that assemble in vivo for combination cancer immunotherapy journal December 2017
Chlorin-Based Nanoscale Metal–Organic Framework Systemically Rejects Colorectal Cancers via Synergistic Photodynamic Therapy and Checkpoint Blockade Immunotherapy journal September 2016
A fresh look at tumor immunosurveillance and immunotherapy journal April 2001
Photodynamic therapy for cancer journal May 2003
CpG DNA: A potent signal for growth, activation, and maturation of human dendritic cells journal August 1999
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs journal February 2016
PD-1–PD-L1 axis: efficient checkpoint blockade against cancer journal December 2014
Electron Injection from Photoexcited Metal–Organic Framework Ligands to Ru 2 Secondary Building Units for Visible-Light-Driven Hydrogen Evolution journal March 2018
Activatable Photosensitizers for Imaging and Therapy journal May 2010
Organelle-Specific Triggered Release of Immunostimulatory Oligonucleotides from Intrinsically Coordinated DNA–Metal–Organic Frameworks with Soluble Exoskeleton journal October 2017
Metal–organic-framework-supported immunostimulatory oligonucleotides for enhanced immune response and imaging journal January 2017
General and Direct Method for Preparing Oligonucleotide-Functionalized Metal–Organic Framework Nanoparticles journal July 2017
In Situ Vaccination With a TLR9 Agonist Induces Systemic Lymphoma Regression: A Phase I/II Study journal October 2010
The Chemistry and Applications of Metal-Organic Frameworks journal August 2013
Imparting Functionality to Biocatalysts via Embedding Enzymes into Nanoporous Materials by a de Novo Approach: Size-Selective Sheltering of Catalase in Metal–Organic Framework Microcrystals journal March 2015
A facile approach to enhance antigen response for personalized cancer vaccination journal March 2018
Approaches to treat immune hot, altered and cold tumours with combination immunotherapies journal January 2019
Nucleobase pairing and photodimerization in a biologically derived metal-organic framework nanoreactor journal April 2019

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