Increased ethanol production by thermophilic microorganisms with deletion of individual hfs hydrogenase subunits
Patent
·
OSTI ID:1650762
Disclosed are methods for engineering bacteria, for example, Thermoanaerobacterium saccharolyticum, that convert biomass to ethanol at high yield by deleting a single gene. Deletion of subunit A or subunit B of the hfs hydrogenase, but not deletion of subunit C or subunit D, results in an increase in ethanol yield.
- Research Organization:
- Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- AC05-00OR22725
- Assignee:
- Trustees of Dartmouth College (Hanover, NH)
- Patent Number(s):
- 10,619,172
- Application Number:
- 15/656,665
- OSTI ID:
- 1650762
- Resource Relation:
- Patent File Date: 07/21/2017
- Country of Publication:
- United States
- Language:
- English
Modification of Hydrogenase Activities in Thermophilic Bacteria to Enhance Ethanol Production
|
patent-application | October 2011 |
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