Comparative Analysis of Microbial Diversity Across Temperature Gradients in Hot Springs From Yellowstone and Iceland

Podar, Peter T.; Yang, Zamin Koo; Björnsdóttir, Snædís H.; Podar, Mircea

doi:10.3389/fmicb.2020.01625

Comparative Analysis of Microbial Diversity Across Temperature Gradients in Hot Springs From Yellowstone and Iceland

Journal Article · Tue Jul 14 00:00:00 EDT 2020 · Frontiers in Microbiology

DOI:https://doi.org/10.3389/fmicb.2020.01625· OSTI ID:1649416

Podar, Peter T. ^[1]; Yang, Zamin Koo ^[1]; Björnsdóttir, Snædís H. ^[2]; ^[1]

Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Biosciences Division
Univ. of Iceland, Reykjavik (Iceland). Faculty of Life and Environmental Sciences,

Geothermal hot springs are a natural setting to study microbial adaptation to a wide range of temperatures reaching up to boiling. Temperature gradients lead to distinct microbial communities that inhabit their optimum niches. We sampled three alkaline, high temperature (80–100°C) hot springs in Yellowstone and Iceland that had cooling outflows and whose microbial communities had not been studied previously. The microbial composition in sediments and mats was determined by DNA sequencing of rRNA gene amplicons. Over three dozen phyla of Archaea and Bacteria were identified, representing over 1700 distinct organisms. We observed a significant non-linear reduction in the number of microbial taxa as the temperature increased from warm (38°C) to boiling. At high taxonomic levels, the community structure was similar between the Yellowstone and Iceland hot springs. We identified potential endemism at the genus level, especially in thermophilic phototrophs, which may have been potentially driven by distinct environmental conditions and dispersal limitations.

View Accepted Manuscript (DOE)

Research Organization:: Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)

Sponsoring Organization:: National Aeronautic and Space Administration (NASA); National Science Foundation (NSF); USDOE

Grant/Contract Number:: AC05-00OR22725

OSTI ID:: 1649416

Journal Information:: Frontiers in Microbiology, Journal Name: Frontiers in Microbiology Journal Issue: 1 Vol. 11; ISSN 1664-302X

Publisher:: Frontiers Research FoundationCopyright Statement

Country of Publication:: United States

Language:: English

References (73)

The effect of sulfide on the blue-green algae of hot springs II. Yellowstone National Park Castenholz, Richard W. Microbial Ecology, Vol. 3, Issue 2 https://doi.org/10.1007/bf02010399	journal	June 1977
Bacterial Distribution Along a 50 °C Temperature Gradient Reveals a Parceled Out Hot Spring Environment Cuecas, A.; Portillo, M. C.; Kanoksilapatham, W. Microbial Ecology, Vol. 68, Issue 4 https://doi.org/10.1007/s00248-014-0437-y	journal	June 2014
Comparative Metagenomics of Eight Geographically Remote Terrestrial Hot Springs Menzel, Peter; Gudbergsdóttir, Sóley Ruth; Rike, Anne Gunn Microbial Ecology, Vol. 70, Issue 2 https://doi.org/10.1007/s00248-015-0576-9	journal	February 2015
New isolates and physiological properties of the Aquificales and description of Thermocrinis albus sp. nov. Eder, Wolfgang; Huber, Robert Extremophiles, Vol. 6, Issue 4 https://doi.org/10.1007/s00792-001-0259-y	journal	March 2002
Tolerance of thermophilic and hyperthermophilic microorganisms to desiccation Beblo, Kristina; Rabbow, Elke; Rachel, Reinhard Extremophiles, Vol. 13, Issue 3 https://doi.org/10.1007/s00792-009-0239-1	journal	March 2009
Detection and analysis of elusive members of a novel and diverse archaeal community within a thermal spring streamer consortium Colman, Daniel R.; Thomas, Raquela; Maas, Kendra R. Extremophiles, Vol. 19, Issue 2 https://doi.org/10.1007/s00792-014-0715-0	journal	December 2014
Microbial diversity and autotrophic activity in Kamchatka hot springs Merkel, Alexander Yu.; Pimenov, Nikolay V.; Rusanov, Igor I. Extremophiles, Vol. 21, Issue 2 https://doi.org/10.1007/s00792-016-0903-1	journal	December 2016
Conservation evaluation and phylogenetic diversity Faith, Daniel P. Biological Conservation, Vol. 61, Issue 1 https://doi.org/10.1016/0006-3207(92)91201-3	journal	January 1992
The chemistry of geothermal waters in Iceland. II. Mineral equilibria and independent variables controlling water compositions Arnórsson, Stefán; Gunnlaugsson, Einar; Svavarsson, Hördur Geochimica et Cosmochimica Acta, Vol. 47, Issue 3 https://doi.org/10.1016/0016-7037(83)90277-6	journal	March 1983
The importance of physical isolation to microbial diversification Papke, R. Thane; Ward, David M. FEMS Microbiology Ecology, Vol. 48, Issue 3 https://doi.org/10.1016/j.femsec.2004.03.013	journal	June 2004
Temperature modulates Fischerella thermalis ecotypes in Porcelana Hot Spring Alcorta, Jaime; Espinoza, Sebastián; Viver, Tomeu Systematic and Applied Microbiology, Vol. 41, Issue 6 https://doi.org/10.1016/j.syapm.2018.05.006	journal	November 2018
Dissolution of primary minerals in natural waters Stefánsson, Andri; Gı́slason, Sigurdur R.; Arnórsson, Stefán Chemical Geology, Vol. 172, Issue 3-4 https://doi.org/10.1016/s0009-2541(00)00262-x	journal	February 2001
Extremophiles and their adaptation to hot environments Stetter, Karl O. FEBS Letters, Vol. 452, Issue 1-2 https://doi.org/10.1016/s0014-5793(99)00663-8	journal	June 1999
Examining the global distribution of dominant archaeal populations in soil Bates, Scott T.; Berg-Lyons, Donna; Caporaso, J. Gregory The ISME Journal, Vol. 5, Issue 5 https://doi.org/10.1038/ismej.2010.171	journal	November 2010
Sediment microbial communities in Great Boiling Spring are controlled by temperature and distinct from water communities Cole, Jessica K.; Peacock, Joseph P.; Dodsworth, Jeremy A. The ISME Journal, Vol. 7, Issue 4 https://doi.org/10.1038/ismej.2012.157	journal	December 2012
Humboldt’s spa: microbial diversity is controlled by temperature in geothermal environments Sharp, Christine E.; Brady, Allyson L.; Sharp, Glen H. The ISME Journal, Vol. 8, Issue 6 https://doi.org/10.1038/ismej.2013.237	journal	January 2014
Ecophysiology of an uncultivated lineage of Aigarchaeota from an oxic, hot spring filamentous ‘streamer’ community Beam, Jacob P.; Jay, Zackary J.; Schmid, Markus C. The ISME Journal, Vol. 10, Issue 1 https://doi.org/10.1038/ismej.2015.83	journal	July 2015
Insights into the phylogeny and coding potential of microbial dark matter Rinke, Christian; Schwientek, Patrick; Sczyrba, Alexander Nature, Vol. 499, Issue 7459 https://doi.org/10.1038/nature12352	journal	July 2013
Practical innovations for high-throughput amplicon sequencing Lundberg, Derek S.; Yourstone, Scott; Mieczkowski, Piotr Nature Methods, Vol. 10, Issue 10 https://doi.org/10.1038/nmeth.2634	journal	September 2013
QIIME allows analysis of high-throughput community sequencing data Caporaso, J. Gregory; Kuczynski, Justin; Stombaugh, Jesse Nature Methods, Vol. 7, Issue 5 https://doi.org/10.1038/nmeth.f.303	journal	April 2010
Microbial biogeography: putting microorganisms on the map Martiny, Jennifer B. Hughes; Bohannan, Brendan J. M.; Brown, James H. Nature Reviews Microbiology, Vol. 4, Issue 2 https://doi.org/10.1038/nrmicro1341	journal	February 2006
Microbial biogeography of 925 geothermal springs in New Zealand Power, Jean F.; Carere, Carlo R.; Lee, Charles K. Nature Communications, Vol. 9, Issue 1 https://doi.org/10.1038/s41467-018-05020-y	journal	July 2018
Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2 Bolyen, Evan; Rideout, Jai Ram; Dillon, Matthew R. Nature Biotechnology, Vol. 37, Issue 8 https://doi.org/10.1038/s41587-019-0209-9	journal	July 2019
Geographical isolation in hot spring cyanobacteria: Geographical isolation in hot spring cyanobacteria Papke, R. Thane; Ramsing, Niels B.; Bateson, Mary M. Environmental Microbiology, Vol. 5, Issue 8 https://doi.org/10.1046/j.1462-2920.2003.00460.x	journal	July 2003
From The Cover: Hydrogen and bioenergetics in the Yellowstone geothermal ecosystem Spear, J. R.; Walker, J. J.; McCollom, T. M. Proceedings of the National Academy of Sciences, Vol. 102, Issue 7, p. 2555-2560 https://doi.org/10.1073/pnas.0409574102	journal	January 2005
The Intersection of Geology, Geochemistry, and Microbiology in Continental Hydrothermal Systems Colman, Daniel R.; Lindsay, Melody R.; Amenabar, Maximiliano J. Astrobiology, Vol. 19, Issue 12 https://doi.org/10.1089/ast.2018.2016	journal	December 2019
Ecological differentiation in planktonic and sediment-associated chemotrophic microbial populations in Yellowstone hot springs Colman, Daniel R.; Feyhl-Buska, Jayme; Robinson, Kirtland J. FEMS Microbiology Ecology, Vol. 92, Issue 9 https://doi.org/10.1093/femsec/fiw137	journal	June 2016
SILVA: a comprehensive online resource for quality checked and aligned ribosomal RNA sequence data compatible with ARB Pruesse, E.; Quast, C.; Knittel, K. Nucleic Acids Research, Vol. 35, Issue 21 https://doi.org/10.1093/nar/gkm864	journal	November 2007
Insights into the evolution of Archaea and eukaryotic protein modifier systems revealed by the genome of a novel archaeal group Nunoura, Takuro; Takaki, Yoshihiro; Kakuta, Jungo Nucleic Acids Research, Vol. 39, Issue 8 https://doi.org/10.1093/nar/gkq1228	journal	December 2010
Hyperthermophiles in the history of life Stetter, Karl O. Philosophical Transactions of the Royal Society B: Biological Sciences, Vol. 361, Issue 1474 https://doi.org/10.1098/rstb.2006.1907	journal	September 2006
Ignisphaera aggregans gen. nov., sp. nov., a novel hyperthermophilic crenarchaeote isolated from hot springs in Rotorua and Tokaanu, New Zealand Niederberger, Thomas D.; Götz, Dorothee K.; McDonald, Ian R. International Journal of Systematic and Evolutionary Microbiology, Vol. 56, Issue 5 https://doi.org/10.1099/ijs.0.63899-0	journal	May 2006
Comparative metagenomic and rRNA microbial diversity characterization using archaeal and bacterial synthetic communities: Metagenomic and rRNA diversity characterization Shakya, Migun; Quince, Christopher; Campbell, James H. Environmental Microbiology, Vol. 15, Issue 6 https://doi.org/10.1111/1462-2920.12086	journal	February 2013
Subsurface processes influence oxidant availability and chemoautotrophic hydrogen metabolism in Yellowstone hot springs Lindsay, Melody R.; Amenabar, Maximiliano J.; Fecteau, Kristopher M. Geobiology, Vol. 16, Issue 6 https://doi.org/10.1111/gbi.12308	journal	July 2018
Hydrothermal ecotones and streamer biofilm communities in the Lower Geyser Basin, Yellowstone National Park: Hydrothermal ecotones and biofilms in Yellowstone Meyer-Dombard, D'Arcy R.; Swingley, Wesley; Raymond, Jason Environmental Microbiology, Vol. 13, Issue 8 https://doi.org/10.1111/j.1462-2920.2011.02476.x	journal	March 2011
Environmental constraints defining the distribution, composition, and evolution of chlorophototrophs in thermal features of Yellowstone National Park: Environmental constraints defining the distribution, composition, and evolution Hamilton, T. L.; Vogl, K.; Bryant, D. A. Geobiology, Vol. 10, Issue 3 https://doi.org/10.1111/j.1472-4669.2011.00296.x	journal	September 2011
Linking geochemical processes with microbial community analysis: successional dynamics in an arsenic-rich, acid-sulphate-chloride geothermal spring Macur, R. E.; Langner, H. W.; Kocar, B. D. Geobiology, Vol. 2, Issue 3 https://doi.org/10.1111/j.1472-4677.2004.00032.x	journal	July 2004
The Thermophilic Cyanophytes of Iceland and the Upper Temperature Limit Castenholz, Richard W. Journal of Phycology, Vol. 5, Issue 4 https://doi.org/10.1111/j.1529-8817.1969.tb02626.x	journal	December 1969
The effects of temperature, pH and sulphide on the community structure of hyperthermophilic streamers in hot springs of northern Thailand: Hyperthermophilic diversity and abiotic variables Purcell, Diane; Sompong, Udomluk; Yim, Lau Chui FEMS Microbiology Ecology, Vol. 60, Issue 3 https://doi.org/10.1111/j.1574-6941.2007.00302.x	journal	June 2007
Diversity of Archaea in Icelandic hot springs based on 16S rRNA and chaperonin genes: Archaeal diversity from neutral hot springs Mirete, Salvador; de Figueras, Carolina G.; González-Pastor, Jose E. FEMS Microbiology Ecology, Vol. 77, Issue 1 https://doi.org/10.1111/j.1574-6941.2011.01095.x	journal	April 2011
Species divergence and the measurement of microbial diversity Lozupone, Catherine A.; Knight, Rob FEMS Microbiology Reviews, Vol. 32, Issue 4 https://doi.org/10.1111/j.1574-6976.2008.00111.x	journal	July 2008
Merging Genomes with Geochemistry in Hydrothermal Ecosystems Reysenbach, A. -L. Science, Vol. 296, Issue 5570 https://doi.org/10.1126/science.1072483	journal	May 2002
Geographic Barriers Isolate Endemic Populations of Hyperthermophilic Archaea Whitaker, R. J. Science, Vol. 301, Issue 5635 https://doi.org/10.1126/science.1086909	journal	August 2003
Limits of Microbial Existence: Temperature and pH Brock, T. D.; Darland, G. K. Science, Vol. 169, Issue 3952 https://doi.org/10.1126/science.169.3952.1316	journal	September 1970
Differences in Temperature and Water Chemistry Shape Distinct Diversity Patterns in Thermophilic Microbial Communities Chiriac, Cecilia M.; Szekeres, Edina; Rudi, Knut Applied and Environmental Microbiology, Vol. 83, Issue 21 https://doi.org/10.1128/AEM.01363-17	journal	August 2017
Quantitative and Qualitative Diversity Measures Lead to Different Insights into Factors That Structure Microbial Communities Lozupone, C. A.; Hamady, M.; Kelley, S. T. Applied and Environmental Microbiology, Vol. 73, Issue 5 https://doi.org/10.1128/aem.01996-06	journal	January 2007
Effects of Abiotic Factors on the Phylogenetic Diversity of Bacterial Communities in Acidic Thermal Springs Mathur, J.; Bizzoco, R. W.; Ellis, D. G. Applied and Environmental Microbiology, Vol. 73, Issue 8 https://doi.org/10.1128/aem.02567-06	journal	January 2007
Bar-Coded Pyrosequencing Reveals Shared Bacterial Community Properties along the Temperature Gradients of Two Alkaline Hot Springs in Yellowstone National Park Miller, S. R.; Strong, A. L.; Jones, K. L. Applied and Environmental Microbiology, Vol. 75, Issue 13 https://doi.org/10.1128/aem.02792-08	journal	May 2009
Adaptation to Hydrogen Sulfide of Oxygenic and Anoxygenic Photosynthesis among Cyanobacteria Cohen, Yehuda; Jørgensen, Bo Barker; Revsbech, Niels Peter Applied and Environmental Microbiology, Vol. 51, Issue 2 https://doi.org/10.1128/aem.51.2.398-407.1986	journal	January 1986
Thermocrinis ruber gen. nov., sp. nov., a Pink-Filament-Forming Hyperthermophilic Bacterium Isolated from Yellowstone National Park Huber, Robert; Eder, Wolfgang; Heldwein, Stefan Applied and Environmental Microbiology, Vol. 64, Issue 10 https://doi.org/10.1128/aem.64.10.3576-3583.1998	journal	October 1998
Evolution of Thermotolerance in Hot Spring Cyanobacteria of the Genus Synechococcus Miller, S. R.; Castenholz, R. W. Applied and Environmental Microbiology, Vol. 66, Issue 10 https://doi.org/10.1128/aem.66.10.4222-4229.2000	journal	October 2000
Highly Ordered Vertical Structure of Synechococcus Populations within the One-Millimeter-Thick Photic Zone of a Hot Spring Cyanobacterial Mat Ramsing, N. B.; Ferris, M. J.; Ward, D. M. Applied and Environmental Microbiology, Vol. 66, Issue 3 https://doi.org/10.1128/aem.66.3.1038-1049.2000	journal	March 2000
Influence of Sulfide and Temperature on Species Composition and Community Structure of Hot Spring Microbial Mats Skirnisdottir, S.; Hreggvidsson, G. O.; Hjorleifsdottir, S. Applied and Environmental Microbiology, Vol. 66, Issue 7 https://doi.org/10.1128/aem.66.7.2835-2841.2000	journal	July 2000
UniFrac: a New Phylogenetic Method for Comparing Microbial Communities Lozupone, C.; Knight, R. Applied and Environmental Microbiology, Vol. 71, Issue 12 https://doi.org/10.1128/aem.71.12.8228-8235.2005	journal	December 2005
Deblur Rapidly Resolves Single-Nucleotide Community Sequence Patterns Amir, Amnon; McDonald, Daniel; Navas-Molina, Jose A. mSystems, Vol. 2, Issue 2 https://doi.org/10.1128/mSystems.00191-16	journal	March 2017
q2-longitudinal: Longitudinal and Paired-Sample Analyses of Microbiome Data Bokulich, Nicholas A.; Dillon, Matthew R.; Zhang, Yilong mSystems, Vol. 3, Issue 6 https://doi.org/10.1128/msystems.00219-18	journal	November 2018
Geochemistry and Dynamics of the Yellowstone National Park Hydrothermal System Fournier, R. O. Annual Review of Earth and Planetary Sciences, Vol. 17, Issue 1 https://doi.org/10.1146/annurev.ea.17.050189.000305	journal	May 1989
Temperature-controlled thermophilic bacterial communities in hot springs of western Sichuan, China Tang, Jie; Liang, Yuanmei; Jiang, Dong BMC Microbiology, Vol. 18, Issue 1 https://doi.org/10.1186/s12866-018-1271-z	journal	October 2018
Development and characterization of stable anaerobic thermophilic methanogenic microbiomes fermenting switchgrass at decreasing residence times Liang, Xiaoyu; Whitham, Jason M.; Holwerda, Evert K. Biotechnology for Biofuels, Vol. 11, Issue 1 https://doi.org/10.1186/s13068-018-1238-1	journal	September 2018
Optimizing taxonomic classification of marker-gene amplicon sequences with QIIME 2’s q2-feature-classifier plugin Bokulich, Nicholas A.; Kaehler, Benjamin D.; Rideout, Jai Ram Microbiome, Vol. 6, Issue 1 https://doi.org/10.1186/s40168-018-0470-z	journal	May 2018
Control of Temperature on Microbial Community Structure in Hot Springs of the Tibetan Plateau Wang, Shang; Hou, Weiguo; Dong, Hailiang PLoS ONE, Vol. 8, Issue 5 https://doi.org/10.1371/journal.pone.0062901	journal	May 2013
Functional Classification of Uncultured “Candidatus Caldiarchaeum subterraneum” Using the Maple System Takami, Hideto; Arai, Wataru; Takemoto, Kazuhiro PLOS ONE, Vol. 10, Issue 7 https://doi.org/10.1371/journal.pone.0132994	journal	July 2015
Cutadapt removes adapter sequences from high-throughput sequencing reads Martin, Marcel EMBnet.journal, Vol. 17, Issue 1 https://doi.org/10.14806/ej.17.1.200	journal	May 2011
Community Structure and Function of High-Temperature Chlorophototrophic Microbial Mats Inhabiting Diverse Geothermal Environments Klatt, Christian G.; Inskeep, William P.; Herrgard, Markus J. Frontiers in Microbiology, Vol. 4 https://doi.org/10.3389/fmicb.2013.00106	journal	January 2013
The molecular dimension of microbial species: 2. Synechococcus strains representative of putative ecotypes inhabiting different depths in the Mushroom Spring microbial mat exhibit different adaptive and acclimative responses to light Nowack, Shane; Olsen, Millie T.; Schaible, George A. Frontiers in Microbiology, Vol. 6 https://doi.org/10.3389/fmicb.2015.00626	journal	June 2015
The Dark Side of the Mushroom Spring Microbial Mat: Life in the Shadow of Chlorophototrophs. I. Microbial Diversity Based on 16S rRNA Gene Amplicons and Metagenomic Sequencing Thiel, Vera; Wood, Jason M.; Olsen, Millie T. Frontiers in Microbiology, Vol. 7 https://doi.org/10.3389/fmicb.2016.00919	journal	June 2016
Abundant and Rare Microbial Biospheres Respond Differently to Environmental and Spatial Factors in Tibetan Hot Springs Zhang, Yanmin; Wu, Geng; Jiang, Hongchen Frontiers in Microbiology, Vol. 9 https://doi.org/10.3389/fmicb.2018.02096	journal	September 2018
Biogeography of American Northwest Hot Spring A/B′-Lineage Synechococcus Populations Becraft, Eric D.; Wood, Jason M.; Cohan, Frederick M. Frontiers in Microbiology, Vol. 11 https://doi.org/10.3389/fmicb.2020.00077	journal	February 2020
Productivity and Community Composition of Low Biomass/High Silica Precipitation Hot Springs: A Possible Window to Earth’s Early Biosphere? Havig, Jeff R.; Hamilton, Trinity L. Life, Vol. 9, Issue 3 https://doi.org/10.3390/life9030064	journal	July 2019
Optimizing taxonomic classification of marker-gene amplicon sequences with QIIME 2’s q2-feature-classifier plugin Bokulich, Nicholas A.; Kaehler, Benjamin D.; Rideout, Jai Ram ETH Zurich https://doi.org/10.3929/ethz-b-000431197	text	January 2018
q2-longitudinal: Longitudinal and Paired-Sample Analyses of Microbiome Data Bokulich, Nicholas A.; Dillon, Matthew R.; Zhang, Yilong ETH Zurich https://doi.org/10.3929/ethz-b-000431246	text	January 2018
VSEARCH: a versatile open source tool for metagenomics Rognes, Torbjorn; Flouri, Tomas; Nichols, Ben Karlsruhe https://doi.org/10.5445/ir/1000062113	text	January 2016
Development and characterization of stable anaerobic thermophilic methanogenic microbiomes fermenting switchgrass at decreasing residence times [Supplemental Data] Whitham, Jason; Holwerda, Evert; Tian, Liang figshare-Supplementary information for journal article at DOI: 10.1186/s13068-018-1238-1, 13 files https://doi.org/10.6084/m9.figshare.c.4224131.v1	collection	September 2018
VSEARCH: a versatile open source tool for metagenomics Rognes, Torbjørn; Flouri, Tomáš; Nichols, Ben PeerJ, Vol. 4 https://doi.org/10.7717/peerj.2584	journal	January 2016

Cited By (1)

Social Interactions Clustering MOOC Students: An Exploratory Study Shi, Lei; Cristea, Alexandra; Alamri, Ahmad arXiv https://doi.org/10.48550/arxiv.2008.03982	preprint	January 2020

Similar Records

The YNP metagenome project: environmental parameters responsible for microbial distribution in the Yellowstone geothermal ecosystem

Journal Article · Mon Dec 31 19:00:00 EST 2012 · Frontiers in Microbiology · OSTI ID:1628082

The Dark Side of the Mushroom Spring Microbial Mat: Life in the Shadow of Chlorophototrophs. II. Metabolic Functions of Abundant Community Members Predicted from Metagenomic Analyses

Journal Article · Mon Jun 05 20:00:00 EDT 2017 · Frontiers in Microbiology · OSTI ID:1424228

The Dark Side of the Mushroom Spring Microbial Mat: Life in the Shadow of Chlorophototrophs. I. Microbial Diversity Based on 16S rRNA Gene Amplicons and Metagenomic Sequencing

Journal Article · Thu Jun 16 20:00:00 EDT 2016 · Frontiers in Microbiology · OSTI ID:1286006

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
biogeography
hot springs
microbial ecology
rRNA amplicons
thermophiles

Comparative Analysis of Microbial Diversity Across Temperature Gradients in Hot Springs From Yellowstone and Iceland

Citation Formats

References (73)

Cited By (1)

Similar Records

Related Subjects