Proteogenomic Characterization of Ovarian HGSC Implicates Mitotic Kinases, Replication Stress in Observed Chromosomal Instability

McDermott, Jason E.; Arshad, Osama A.; Petyuk, Vladislav A.; Fu, Yi; Gritsenko, Marina A.; Clauss, Therese R.; Moore, Ronald J.; Schepmoes, Athena A.; Zhao, Rui; Monroe, Matthew E.; Schnaubelt, Michael; Tsai, Chia-Feng; Payne, Samuel H.; Huang, Chen; Wang, Liang-Bo; Foltz, Steven; Wyczalkowski, Matthew; Wu, Yige; Song, Ehwang; Brewer, Molly A.; Thiagarajan, Mathangi; Kinsinger, Christopher R.; Robles, Ana I.; Boja, Emily S.; Rodriguez, Henry; Chan, Daniel W.; Zhang, Bing; Zhang, Zhen; Ding, Li; Smith, Richard D.; Liu, Tao; Rodland, Karin D.

doi:10.1016/j.xcrm.2020.100004

Proteogenomic Characterization of Ovarian HGSC Implicates Mitotic Kinases, Replication Stress in Observed Chromosomal Instability

Journal Article · Wed Apr 01 00:00:00 EDT 2020 · Cell Reports Medicine

DOI:https://doi.org/10.1016/j.xcrm.2020.100004· OSTI ID:1829332

McDermott, Jason E.; Arshad, Osama A.; ; Fu, Yi; Gritsenko, Marina A.; Clauss, Therese R.; Moore, Ronald J.; Schepmoes, Athena A.; Zhao, Rui; ; ; ; ; Huang, Chen; ; ; ; Wu, Yige; Song, Ehwang; Brewer, Molly A. more »

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Research Organization:: Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)

Sponsoring Organization:: National Cancer Institute (NCI); National Institutes of Health (NIH); USDOE

Contributing Organization:: Clinical Proteomic Tumor Analysis Consortium Investigators

Grant/Contract Number:: AC05-76RL01830

OSTI ID:: 1829332

Alternate ID(s):: OSTI ID: 1642074

Report Number(s):: PNNL-SA--145681; S2666379120300045; 100004; PII: S2666379120300045

Journal Information:: Cell Reports Medicine, Journal Name: Cell Reports Medicine Journal Issue: 1 Vol. 1; ISSN 2666-3791

Publisher:: ElsevierCopyright Statement

Country of Publication:: United States

Language:: English

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59 BASIC BIOLOGICAL SCIENCES
Proteogenomics
ovarian cancer
phosphoproteomics
proteomics
Fallopian tube
homologous repair deficiency
replication stress
high-grade serous cancer

Proteogenomic Characterization of Ovarian HGSC Implicates Mitotic Kinases, Replication Stress in Observed Chromosomal Instability

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