Systems and methods for detecting metal ion concentrations in subjects

Chang, Christopher J.; Long, Jeffrey R.; Lee, Sumin; Barin, Gokhan

Title: Systems and methods for detecting metal ion concentrations in subjects

Patent · Tue Mar 31 00:00:00 EDT 2020

OSTI ID:1637767

Chang, Christopher J.; Long, Jeffrey R.; Lee, Sumin; Barin, Gokhan

A method of selective detection of a concentration of a metal ion species in a subject is provided in which a biofluid sample is obtained from the subject. The biofluid sample is exposed to a functionalized porous aromatic polymer. The polymer selectively captures and concentrates the metal ion species from the biofluid. Subsequently, the biofluid is washed from the polymer. The polymer is then exposed to a solution comprising a colorimetric indicator that extracts the metal ion species from the washed polymer thereby changing a color of the solution as a function of an amount of the metal ion species in the polymer. The concentration of the metal ion species in the subject is then spectroscopically determined from the color of the solution.

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Research Organization:: Univ. of California, Oakland, CA (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: SC0001015

Assignee:: The Regents of the University of California (Oakland, CA)

Patent Number(s):: 10,605,799

Application Number:: 15/593,117

OSTI ID:: 1637767

Resource Relation:: Patent File Date: 05/11/2017

Country of Publication:: United States

Language:: English

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