A Quantitative Index of Substrate Promiscuity †
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journal
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January 2008 |
The Evolutionary Origins of Detoxifying Enzymes: THE MAMMALIAN SERUM PARAOXONASES (PONs) RELATE TO BACTERIAL HOMOSERINE LACTONASES
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journal
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June 2013 |
Overview of the CCP 4 suite and current developments
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journal
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March 2011 |
Crystallization and preliminary X-ray diffraction analysis of hydroxynitrile lyase from cassava ( Manihot esculenta )
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journal
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April 1999 |
Role of residual structure in the unfolded state of a thermophilic protein
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journal
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September 2003 |
Prunus armeniaca hydroxynitrile lyase (ParsHNL)-catalyzed asymmetric synthesis of cyanohydrins from sterically demanding aromatic aldehydes
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journal
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July 2009 |
Uneven twins: Comparison of two enantiocomplementary hydroxynitrile lyases with α/β-hydrolase fold
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May 2009 |
Assessing the Accuracy of Ancestral Protein Reconstruction Methods
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journal
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January 2006 |
Experimental evidence for the thermophilicity of ancestral life
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journal
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June 2013 |
Inferring the palaeoenvironment of ancient bacteria on the basis of resurrected proteins
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journal
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September 2003 |
Structural and functional analysis of hydroxynitrile lyase from Baliospermum montanum with crystal structure, molecular dynamics and enzyme kinetics
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journal
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December 2014 |
Comparison of Five Protein Engineering Strategies for Stabilizing an α/β-Hydrolase
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journal
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November 2017 |
Catalytic Versatility and Backups in Enzyme Active Sites: The Case of Serum Paraoxonase 1
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May 2012 |
How good are my data and what is the resolution?
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journal
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June 2013 |
Explosive Radiation of Malpighiales Supports a Mid‐Cretaceous Origin of Modern Tropical Rain Forests
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journal
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March 2005 |
Structural and biochemical studies identify tobacco SABP2 as a methyl salicylate esterase and implicate it in plant innate immunity
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journal
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January 2005 |
RAxML-VI-HPC: maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models
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journal
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August 2006 |
High-affinity salicylic acid-binding protein 2 is required for plant innate immunity and has salicylic acid-stimulated lipase activity
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journal
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December 2003 |
XDS
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journal
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January 2010 |
Inference of Macromolecular Assemblies from Crystalline State
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journal
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September 2007 |
Development of Sensitive Esterase Assays Based on α-Cyano-Containing Esters
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journal
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December 2001 |
Uncovering divergent evolution of α/β-hydrolases: a surprising residue substitution needed to convert Hevea brasiliensis hydroxynitrile lyase into an esterase
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journal
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January 2014 |
Structural determinants of the enantioselectivity of the hydroxynitrile lyase from Hevea brasiliensis
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journal
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March 2007 |
Origins of Specificity and Promiscuity in Metabolic Networks
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journal
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November 2011 |
A New S -Hydroxynitrile Lyase from Baliospermum montanum —Its Structure, Molecular Dynamics Simulation, and Improvement by Protein Engineering
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journal
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April 2016 |
Enzyme promiscuity: mechanism and applications
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journal
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May 2007 |
Mechanism of cyanogenesis: the crystal structure of hydroxynitrile lyase from Hevea brasiliensis
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journal
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July 1996 |
Stability effects of mutations and protein evolvability
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journal
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October 2009 |
Single-molecule paleoenzymology probes the chemistry of resurrected enzymes
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journal
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April 2011 |
Thermodynamic Differences among Homologous Thermophilic and Mesophilic Proteins †
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journal
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November 2001 |
Prediction of sequence-dependent and mutational effects on the aggregation of peptides and proteins
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journal
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September 2004 |
Thermodynamic System Drift in Protein Evolution
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journal
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November 2014 |
Analysis of temperature factor distribution in high-resolution protein structures
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journal
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December 1997 |
MolProbity : all-atom structure validation for macromolecular crystallography
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journal
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December 2009 |
Cooperative Electrostatic Interactions Drive Functional Evolution in the Alkaline Phosphatase Superfamily
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journal
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July 2015 |
Features and development of Coot
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journal
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March 2010 |
Promiscuity and electrostatic flexibility in the alkaline phosphatase superfamily
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journal
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April 2016 |
REFMAC 5 for the refinement of macromolecular crystal structures
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journal
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March 2011 |
Real-Time Evolution of New Genes by Innovation, Amplification, and Divergence
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journal
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October 2012 |
On the Potential Origins of the High Stability of Reconstructed Ancestral Proteins
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journal
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July 2016 |
Divergent Evolution of Enzymatic Function: Mechanistically Diverse Superfamilies and Functionally Distinct Suprafamilies
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journal
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June 2001 |
The thermostability and specificity of ancient proteins
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journal
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June 2016 |
Evolution of enzyme superfamilies
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October 2006 |
Catalytic Promiscuity of Ancestral Esterases and Hydroxynitrile Lyases
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journal
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January 2016 |
How the Same Core Catalytic Machinery Catalyzes 17 Different Reactions: the Serine-Histidine-Aspartate Catalytic Triad of α/β-Hydrolase Fold Enzymes
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journal
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September 2015 |
A Measure of the Promiscuity of Proteins and Characteristics of Residues in the Vicinity of the Catalytic Site That Regulate Promiscuity
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journal
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February 2012 |
Macromolecular TLS Refinement in REFMAC at Moderate Resolutions
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book
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January 2003 |
Purification and characterization of hydroxynitrile lyase from Hevea brasiliensis
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journal
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March 1996 |
Stability of the enzyme (S)-hydroxynitrile lyase from Hevea brasiliensis
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journal
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September 1998 |
Hyperstability and Substrate Promiscuity in Laboratory Resurrections of Precambrian β-Lactamases
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journal
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February 2013 |
CO2 as a primary driver of Phanerozoic climate
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journal
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January 2004 |
SwissDock, a protein-small molecule docking web service based on EADock DSS
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journal
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May 2011 |
S-selective hydroxynitrile lyase from a plant Baliospermum montanum: Molecular characterization of recombinant enzyme
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journal
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May 2011 |
Reconstructing Ancient Proteins to Understand the Causes of Structure and Function
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journal
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May 2017 |
Protein Identification and Analysis Tools on the ExPASy Server
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book
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January 2005 |
MOLEonline: a web-based tool for analyzing channels, tunnels and pores (2018 update)
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journal
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April 2018 |
Ohno's dilemma: Evolution of new genes under continuous selection
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journal
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October 2007 |
Denaturant m values and heat capacity changes: Relation to changes in accessible surface areas of protein unfolding
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journal
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May 1996 |
Evolution of a Catalytic Mechanism
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journal
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December 2015 |
Differential Active Site Loop Conformations Mediate Promiscuous Activities in the Lactonase SsoPox
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journal
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September 2013 |
Palaeotemperature trend for Precambrian life inferred from resurrected proteins
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journal
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February 2008 |
On the Origin and Evolution of Thermophily: Reconstruction of Functional Precambrian Enzymes from Ancestors of Bacillus
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journal
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October 2011 |
Phaser crystallographic software
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journal
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July 2007 |
Electrospray ionization mass spectrometry, circular dichroism and SAXS studies of the (S)-hydroxynitrile lyase from Hevea brasiliensis
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journal
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January 2001 |