Skip to main content
OSTI.GOVU.S. Department of Energy Office of Scientific and Technical Information
U.S. Department of Energy
Office of Scientific and Technical Information
 

The NAS Perchlorate Review: Adverse Effects?

Journal Article · · Environmental Health Perspectives
 [1];  [2];  [3];  [4]
  1. Univ. of Colorado School of Medicine, Denver, CO (United States); DOE/OSTI
  2. Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
  3. Univ. of Oklahoma Health, Sciences Center, Oklahoma City, OK (United States)
  4. Harvard Medical School, Boston, MA (United States)
+ Show Author Affiliations

Ginsberg and Rice (2005) argued that the reference dose for perchlorate of 0.0007 mg/kg per day recommended by the National Academy of Sciences (NAS) Committee to Assess the Health Implications of Perchlorate Ingestion is not adequately protective. As members of the committee, we disagree.

Research Organization:
Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
Sponsoring Organization:
USDOE Office of Science (SC)
Grant/Contract Number:
AC05-76RL01830
OSTI ID:
1629200
Journal Information:
Environmental Health Perspectives, Journal Name: Environmental Health Perspectives Journal Issue: 11 Vol. 113; ISSN 0091-6765
Publisher:
National Institute of Environmental Health SciencesCopyright Statement
Country of Publication:
United States
Language:
English

References (9)

Early adaptation of thyrotropin and thyroglobulin secretion to experimentally decreased iodine supply in man journal October 1992
Urinary iodine excretion in pregnant women residing in areas with adequate iodine intake journal February 2003
Alteration of Liver Cell Function and Proliferation: Differentiation Between Adaptation and Toxicity journal January 2002
Does Perchlorate in Drinking Water Affect Thyroid Function in Newborns or School-Age Children? journal June 2000
Prevalence of maternal dietary iodine insufficiency in the north east of England: implications for the fetus journal September 2004
The Sodium/Iodide Symporter (NIS): Characterization, Regulation, and Medical Significance journal February 2003
Health effects assessment for environmental perchlorate contamination: the dose response for inhibition of thyroidal radioiodine uptake in humans. journal September 2002
The NAS Perchlorate Review: Questions Remain about the Perchlorate RfD journal September 2005
Early adaptation of thyrotropin and thyroglobulin secretion to experimentally decreased iodine supply in man journal October 1992

Cited By (5)

Developmental Exposure to Perchlorate Alters Synaptic Transmission in Hippocampus of the Adult Rat journal June 2008
The NAS Perchlorate Review: Ginsberg et al. Respond journal November 2005
Development of a Health-Protective Drinking Water Level for Perchlorate journal June 2006
Evaluation of the U.S. EPA/OSWER Preliminary Remediation Goal for Perchlorate in Groundwater: Focus on Exposure to Nursing Infants journal March 2007
The Na + /I − symporter (NIS) mediates electroneutral active transport of the environmental pollutant perchlorate journal December 2007

Similar Records

The NAS Perchlorate Review: Adverse Effects?
Journal Article · Mon Oct 31 23:00:00 EST 2005 · Environmental Health Perspectives · OSTI ID:993669
Review of the selenium health criteria document. Final report
Technical Report · Tue Jul 19 00:00:00 EDT 1988 · OSTI ID:6864974
U.S. NRC staff views on the technical bases for Yucca Mountain standards
Conference · Fri Dec 30 23:00:00 EST 1994 · OSTI ID:60766

Related Subjects

59 BASIC BIOLOGICAL SCIENCES