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Genome Sequences of Two Carbapenemase-Resistant Klebsiella pneumoniae ST258 Isolates

Journal Article · · Genome Announcements
 [1];  [2];  [2];  [2];  [3];  [4];  [5];  [2];  [6]
  1. California State Univ. (CalState), Fullerton, CA (United States). Center for Applied Biotechnology Studies, Dept. of Biological Science; Institute of Medical Microbiology and Parasitology (IMPaM CONICET-UBA), Buenos Aires (Argentina); DOE/OSTI
  2. Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
  3. Univ. of North Carolina, Chapel Hill, NC (United States)
  4. Louis Stokes Cleveland Dept. of Veterans Affairs Medical Center, Cleveland, OH (United States)
  5. Louis Stokes Cleveland Dept. of Veterans Affairs Medical Center, Cleveland, OH (United States); Case Western Reserve Univ. School of Medicine, Cleveland, OH (United States). Dept. of Medicine
  6. California State Univ. (CalState), Fullerton, CA (United States). Center for Applied Biotechnology Studies, Dept. of Biological Science
+ Show Author Affiliations

Klebsiella pneumoniae, an ESKAPE group (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species) pathogen, has acquired multiple antibiotic resistance genes and is becoming a serious public health threat. Here, we report the genome sequences of two representative strains of K. pneumoniae from the emerging K. pneumoniae carbapenemase (KPC) outbreak in northeast Ohio belonging to sequence type 258 (ST258) (isolates Kb140 and Kb677, which were isolated from blood and urine, respectively). Both isolates harbor a $$bla_{\text{KPC}}$$ gene, and strain Kb140 carries $$bla_{\text{KPC-2}}$$, while Kb677 carries $$bla_{\text{KPC-3}}$$.

Research Organization:
Los Alamos National Laboratory (LANL), Los Alamos, NM (United States); USDOE Joint Genome Institute (JGI), Walnut Creek, CA (United States)
Sponsoring Organization:
USDOE Office of Science (SC), Biological and Environmental Research (BER). Biological Systems Science Division; Public Health Service; Cleveland Department of Veterans Affairs; Geriatric Research Education and Clinical Center VISN 10; National Institutes of Health (NIH); National Institute of Allergy and Infectious Diseases (NIAID); Translational Science Collaborative of Cleveland; National Center for Advancing Translational Sciences (NCATS)
Grant/Contract Number:
AC02-05CH11231
OSTI ID:
1629085
Journal Information:
Genome Announcements, Journal Name: Genome Announcements Journal Issue: 3 Vol. 2; ISSN 2169-8287
Publisher:
American Society for MicrobiologyCopyright Statement
Country of Publication:
United States
Language:
English

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Cited By (1)

Small Klebsiella pneumoniae Plasmids: Neglected Contributors to Antibiotic Resistance journal September 2019

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59 BASIC BIOLOGICAL SCIENCES