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HIV vaccine design and the neutralizing antibody problem
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Broadly Neutralizing Human Anti-HIV Antibody 2G12 Is Effective in Protection against Mucosal SHIV Challenge Even at Low Serum Neutralizing Titers
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Limited Neutralizing Antibody Specificities Drive Neutralization Escape in Early HIV-1 Subtype C Infection
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The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection
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Molecular Architectures of Trimeric SIV and HIV-1 Envelope Glycoproteins on Intact Viruses: Strain-Dependent Variation in Quaternary Structure
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December 2010 |
Low-Dose Mucosal Simian Immunodeficiency Virus Infection Restricts Early Replication Kinetics and Transmitted Virus Variants in Rhesus Monkeys
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August 2010 |
Escape from Autologous Neutralizing Antibodies in Acute/Early Subtype C HIV-1 Infection Requires Multiple Pathways
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September 2009 |
Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9
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November 2011 |
Immune and Genetic Correlates of Vaccine Protection Against Mucosal Infection by SIV in Monkeys
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May 2011 |
Generation of Transmitted/Founder HIV-1 Infectious Molecular Clones and Characterization of Their Replication Capacity in CD4 T Lymphocytes and Monocyte-Derived Macrophages
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December 2011 |
Broad neutralization coverage of HIV by multiple highly potent antibodies
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September 2011 |
Inflammatory Genital Infections Mitigate a Severe Genetic Bottleneck in Heterosexual Transmission of Subtype A and C HIV-1
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January 2009 |
Analysis of Neutralization Specificities in Polyclonal Sera Derived from Human Immunodeficiency Virus Type 1-Infected Individuals
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November 2008 |
A Novel Antiviral Intervention Results in More Accurate Assessment of Human Immunodeficiency Virus Type 1 Replication Dynamics and T-Cell Decay In Vivo
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April 2003 |
The Role of Antibodies in HIV Vaccines
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March 2010 |
Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques
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June 2009 |
Rapid Escape from Preserved Cross-Reactive Neutralizing Humoral Immunity without Loss of Viral Fitness in HIV-1-Infected Progressors and Long-Term Nonprogressors
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January 2010 |
Estimation of the Initial Viral Growth Rate and Basic Reproductive Number during Acute HIV-1 Infection
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March 2010 |
Analysis of a Clonal Lineage of HIV-1 Envelope V2/V3 Conformational Epitope-Specific Broadly Neutralizing Antibodies and Their Inferred Unmutated Common Ancestors
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July 2011 |
Detection of minor drug-resistant populations by parallel allele-specific sequencing
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January 2007 |
Structure of a V3-Containing HIV-1 gp120 Core
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November 2005 |
Neutralizing Antibody Responses in Acute Human Immunodeficiency Virus Type 1 Subtype C Infection
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April 2007 |
Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody
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June 1998 |
Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection
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January 1995 |
Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection
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June 2009 |
HIV-1 Dynamics in Vivo: Virion Clearance Rate, Infected Cell Life-Span, and Viral Generation Time
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March 1996 |
Cell-to-cell spread of HIV permits ongoing replication despite antiretroviral therapy
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August 2011 |
The B Cell Response Is Redundant and Highly Focused on V1V2 during Early Subtype C Infection in a Zambian Seroconverter
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October 2010 |
Neutralizing antibodies generated during natural HIV-1 infection: good news for an HIV-1 vaccine?
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June 2009 |
Wide Variation in the Multiplicity of HIV-1 Infection among Injection Drug Users
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April 2010 |
Tiered Categorization of a Diverse Panel of HIV-1 Env Pseudoviruses for Assessment of Neutralizing Antibodies
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November 2009 |
Genetic and Neutralization Properties of Subtype C Human Immunodeficiency Virus Type 1 Molecular env Clones from Acute and Early Heterosexually Acquired Infections in Southern Africa
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September 2006 |
Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility
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December 2009 |
Determinants of Human Immunodeficiency Virus Type 1 Escape from the Primary CD8+ Cytotoxic T Lymphocyte Response
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November 2004 |
Broad and Potent Neutralizing Antibody Responses Elicited in Natural HIV-2 Infection
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October 2011 |
Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1
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May 2009 |
Structural Comparison of HIV-1 Envelope Spikes with and without the V1/V2 Loop
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December 2010 |
Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection
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May 2008 |
Fitness Costs and Diversity of the Cytotoxic T Lymphocyte (CTL) Response Determine the Rate of CTL Escape during Acute and Chronic Phases of HIV Infection
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August 2011 |
Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand
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December 2009 |
Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01
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July 2010 |
Evidence for Potent Autologous Neutralizing Antibody Titers and Compact Envelopes in Early Infection with Subtype C Human Immunodeficiency Virus Type 1
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June 2006 |
HIV Evolution in Early Infection: Selection Pressures, Patterns of Insertion and Deletion, and the Impact of APOBEC
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May 2009 |
High Multiplicity Infection by HIV-1 in Men Who Have Sex with Men
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May 2010 |
A Limited Number of Simian Immunodeficiency Virus (SIV) env Variants Are Transmitted to Rhesus Macaques Vaginally Inoculated with SIVmac251
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May 2010 |
Modelling viral and immune system dynamics
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January 2002 |
Neutralizing antibody responses drive the evolution of human immunodeficiency virus type 1 envelope during recent HIV infection
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December 2005 |
Potent Intratype Neutralizing Activity Distinguishes Human Immunodeficiency Virus Type 2 (HIV-2) from HIV-1
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November 2011 |
Dynamics of HIV viremia and antibody seroconversion in plasma donors: implications for diagnosis and staging of primary HIV infection
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January 2003 |
Rapid evolution of the neutralizing antibody response to HIV type 1 infection
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March 2003 |
Potent Autologous and Heterologous Neutralizing Antibody Responses Occur in HIV-2 Infection across a Broad Range of Infection Outcomes
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November 2011 |
Antiviral pressure exerted by HIV-l-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus
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February 1997 |
Molecular architecture of native HIV-1 gp120 trimers
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July 2008 |
Protection of Macaques against Pathogenic Simian/Human Immunodeficiency Virus 89.6PD by Passive Transfer of Neutralizing Antibodies
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January 1999 |
Cell-to-Cell Transfer of HIV-1 via Virological Synapses Leads to Endosomal Virion Maturation that Activates Viral Membrane Fusion
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December 2011 |
The C3-V4 Region Is a Major Target of Autologous Neutralizing Antibodies in Human Immunodeficiency Virus Type 1 Subtype C Infection
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December 2007 |
Transmission of Single HIV-1 Genomes and Dynamics of Early Immune Escape Revealed by Ultra-Deep Sequencing
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August 2010 |
Antibody neutralization and escape by HIV-1
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March 2003 |
Estimating time since infection in early homogeneous HIV-1 samples using a poisson model
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October 2010 |
Autologous Neutralizing Antibodies to the Transmitted/Founder Viruses Emerge Late after Simian Immunodeficiency Virus SIVmac251 Infection of Rhesus Monkeys
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March 2010 |
Modeling sequence evolution in acute HIV-1 infection
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November 2009 |
Immunotypes of a Quaternary Site of HIV-1 Vulnerability and Their Recognition by Antibodies
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February 2011 |
Specificity of the autologous neutralizing antibody response
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January 2009 |
Roles of HIV-1 Env Variable Regions in Viral Neutralization and Vaccine Development
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November 2007 |
Specific Antibody Responses to Vaccination with Bivalent CM235/SF2 gp120: Detection of Homologous and Heterologous Neutralizing Antibody to Subtype E (CRF01.AE) HIV Type 1
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September 2003 |
Viral dynamics in human immunodeficiency virus type 1 infection
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January 1995 |
Viral Dynamics of Acute HIV-1 Infection
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September 1999 |
High titer HIV-1 V3-specific antibodies with broad reactivity but low neutralizing potency in acute infection and following vaccination
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May 2009 |
Role of V1V2 and Other Human Immunodeficiency Virus Type 1 Envelope Domains in Resistance to Autologous Neutralization during Clade C Infection
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November 2006 |
Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection
- F., Salazar-Gonzalez, Jesus; P., Busch, Michael; S., Perelson, Alan
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The University of North Carolina at Chapel Hill University Libraries
https://doi.org/10.17615/f6s9-vz03
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text
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January 2008 |
Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques
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text
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January 2009 |
Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection
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text
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January 2009 |
For HIV, It's Never Too Late to Grow Up
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journal
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December 2011 |