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HIV vaccine design and the neutralizing antibody problem
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Electrostatics of nanosystems: Application to microtubules and the ribosome
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Generation of a neutralization-resistant variant of HIV-1 is due to selection for a point mutation in the envelope gene
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Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody
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Novel Ring Structure in the gp41 Trimer of Human Immunodeficiency Virus Type 1 That Modulates Sensitivity and Resistance to Broadly Neutralizing Antibodies
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Vaccine-delivered HIV envelope inhibits CD4+ T-cell activation, a mechanism for poor HIV vaccine responses
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Highly complex neutralization determinants on a monophyletic lineage of newly transmitted subtype C HIV-1 Env clones from India
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Mechanism of Human Immunodeficiency Virus Type 1 Resistance to Monoclonal Antibody b12 That Effectively Targets the Site of CD4 Attachment
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Access of Antibody Molecules to the Conserved Coreceptor Binding Site on Glycoprotein gp120 Is Sterically Restricted on Primary Human Immunodeficiency Virus Type 1
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September 2003 |
Rational Modifications of HIV-1 Envelope Glycoproteins for Immunogen Design
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Antibodies to CD4-induced sites in HIV gp120 correlate with the control of SHIV challenge in macaques vaccinated with subunit immunogens
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October 2007 |
Immunization with Recombinant Canarypox Vectors Expressing Membrane-Anchored Glycoprotein 120 Followed by Glycoprotein 160 Boosting Fails to Generate Antibodies That Neutralize R5 Primary Isolates of Human Immunodeficiency Virus Type 1
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Aiming to induce broadly reactive neutralizing antibody responses with HIV-1 vaccine candidates
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Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection
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October 2005 |
HIV gp41 C-terminal Heptad Repeat Contains Multifunctional Domains: RELATION TO MECHANISMS OF ACTION OF ANTI-HIV PEPTIDES
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February 2007 |
Short Communication: Fine Definition of a Conserved CCR5-Binding Region on the Human Immunodeficiency Virus Type 1 Glycoprotein 120
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Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand
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Enhanced Exposure of the CD4-Binding Site to Neutralizing Antibodies by Structural Design of a Membrane-Anchored Human Immunodeficiency Virus Type 1 gp120 Domain
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Analysis of the neutralizing antibody response elicited in rabbits by repeated inoculation with trimeric HIV-1 envelope glycoproteins
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HIV-1 Envelope Triggers Polyclonal Ig Class Switch Recombination through a CD40-Independent Mechanism Involving BAFF and C-Type Lectin Receptors
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Broadly Neutralizing Anti-HIV Antibody 4E10 Recognizes a Helical Conformation of a Highly Conserved Fusion-Associated Motif in gp41
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February 2005 |
Structural Rationale for the Broad Neutralization of HIV-1 by Human Monoclonal Antibody 447-52D
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Correlation between Immunologic Responses to a Recombinant Glycoprotein 120 Vaccine and Incidence of HIV‐1 Infection in a Phase 3 HIV‐1 Preventive Vaccine Trial
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Sequential CD4-Coreceptor Interactions in Human Immunodeficiency Virus Type 1 Env Function: Soluble CD4 Activates Env for Coreceptor-Dependent Fusion and Reveals Blocking Activities of Antibodies against Cryptic Conserved Epitopes on gp120
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Full-Length Human Immunodeficiency Virus Type 1 Genomes from Subtype C-Infected Seroconverters in India, with Evidence of Intersubtype Recombination
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Cardiolipin Polyspecific Autoreactivity in Two Broadly Neutralizing HIV-1 Antibodies
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A group M consensus envelope glycoprotein induces antibodies that neutralize subsets of subtype B and C HIV-1 primary viruses
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Dissecting the Neutralizing Antibody Specificities of Broadly Neutralizing Sera from Human Immunodeficiency Virus Type 1-Infected Donors
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Factors Associated with the Development of Cross-Reactive Neutralizing Antibodies during Human Immunodeficiency Virus Type 1 Infection
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Crystal Structure of a Neutralizing Human IgG Against HIV-1: A Template for Vaccine Design
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Statistical significance for genomewide studies
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Founder Effects in the Assessment of HIV Polymorphisms and HLA Allele Associations
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HIV-1 gp120 Mannoses Induce Immunosuppressive Responses from Dendritic Cells
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HIV Entry and Its Inhibition
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Structures of HIV-1 gp120 Envelope Glycoproteins from Laboratory-Adapted and Primary Isolates
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VMD: Visual molecular dynamics
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Safety and Immunogenicity of an HIV Subtype B and E Prime‐Boost Vaccine Combination in HIV‐Negative Thai Adults
- Nitayaphan, Sorachai; Pitisuttithum, Punnee; Karnasuta, Chitraporn
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The Journal of Infectious Diseases, Vol. 190, Issue 4
https://doi.org/10.1086/422258
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HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites
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Challenges for structure-based HIV vaccine design
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Human Immunodeficiency Virus (HIV) gp41 Escape Mutants: Cross-Resistance to Peptide Inhibitors of HIV Fusion and Altered Receptor Activation of gp120
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April 2005 |
Randomized, Double‐Blind, Placebo‐Controlled Efficacy Trial of a Bivalent Recombinant Glycoprotein 120 HIV‐1 Vaccine among Injection Drug Users in Bangkok, Thailand
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Characterization of CD4-Induced Epitopes on the HIV Type 1 gp120 Envelope Glycoprotein Recognized by Neutralizing Human Monoclonal Antibodies
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Analysis of Neutralization Specificities in Polyclonal Sera Derived from Human Immunodeficiency Virus Type 1-Infected Individuals
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An Immune-Selected Point Mutation in the Transmembrane Protein of Human Immunodeficiency Virus Type 1 (HXB2-Env:Ala 582(→ Thr)) Decreases Viral Neutralization by Monoclonal Antibodies to the CD4-Binding Site
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Concordant Modulation of Neutralization Resistance and High Infectivity of the Primary Human Immunodeficiency Virus Type 1 MN Strain and Definition of a Potential gp41 Binding Site in gp120
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Antibody Specificities Associated with Neutralization Breadth in Plasma from Human Immunodeficiency Virus Type 1 Subtype C-Infected Blood Donors
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Leveraging Hierarchical Population Structure in Discrete Association Studies
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Profiling the Specificity of Neutralizing Antibodies in a Large Panel of Plasmas from Patients Chronically Infected with Human Immunodeficiency Virus Type 1 Subtypes B and C
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A Global Neutralization Resistance Phenotype of Human Immunodeficiency Virus Type 1 Is Determined by Distinct Mechanisms Mediating Enhanced Infectivity and Conformational Change of the Envelope Complex
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Epitope mapping and characterization of a novel CD4-induced human monoclonal antibody capable of neutralizing primary HIV-1 strains
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A Conserved HIV gp120 Glycoprotein Structure Involved in Chemokine Receptor Binding
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Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target
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Structural and immunogenicity studies of a cleaved, stabilized envelope trimer derived from subtype A HIV-1
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Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120
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