Link synthetic lethality to drug sensitivity of cancer cells
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journal
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December 2017 |
Predicting Outcomes of Hormone and Chemotherapy in the Molecular Taxonomy of Breast Cancer International Consortium (METABRIC) Study by Biochemically-inspired Machine Learning
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journal
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January 2016 |
Predicting Outcomes of Hormone and Chemotherapy in the Molecular Taxonomy of Breast Cancer International Consortium (METABRIC) Study by Biochemically-inspired Machine Learning
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journal
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January 2016 |
Co-expression of key gene modules and pathways of human breast cancer cell lines
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journal
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July 2019 |
Quantification of sensitivity and resistance of breast cancer cell lines to anti-cancer drugs using GR metrics
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journal
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November 2017 |
Pan-cancer analysis of transcriptional metabolic dysregulation using The Cancer Genome Atlas
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journal
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December 2018 |
A community effort to assess and improve drug sensitivity prediction algorithms
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journal
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June 2014 |
Widespread intron retention diversifies most cancer transcriptomes
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journal
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May 2015 |
Targeting PLK1 overcomes T-DM1 resistance via CDK1-dependent phosphorylation and inactivation of Bcl-2/xL in HER2-positive breast cancer
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journal
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February 2018 |
CusVarDB: A tool for building customized sample-specific variant protein database from next-generation sequencing datasets
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journal
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January 2020 |
CusVarDB: A tool for building customized sample-specific variant protein database from next-generation sequencing datasets
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journal
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January 2020 |
Germline single nucleotide polymorphisms in ERBB3 and BARD1 genes result in a worse relapse free survival response for HER2-positive breast cancer patients treated with adjuvant based docetaxel, carboplatin and trastuzumab (TCH)
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journal
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August 2018 |
A multifunctional DNA nano-scorpion for highly efficient targeted delivery of mRNA therapeutics
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journal
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July 2018 |
Competitive endogenous RNA is an intrinsic component of EMT regulatory circuits and modulates EMT
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journal
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April 2019 |
Proteolytic processing of PD-L1 by ADAM proteases in breast cancer cells
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journal
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December 2019 |
Prognostic Power of a Tumor Differentiation Gene Signature for Bladder Urothelial Carcinomas
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journal
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January 2018 |
Triple-Negative Breast Cancer: Current Understanding and Future Therapeutic Breakthrough Targeting Cancer Stemness
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journal
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September 2019 |
Revisiting inconsistency in large pharmacogenomic studies
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journal
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September 2015 |
Comprehensive comparison of molecular portraits between cell lines and tumors in breast cancer
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journal
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August 2016 |
Dual inhibition of glutaminase and carnitine palmitoyltransferase decreases growth and migration of glutaminase inhibition–resistant triple-negative breast cancer cells
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journal
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June 2019 |
Methodological Challenges in Translational Drug Response Modeling in Cancer
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posted_content
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January 2019 |
Multi-Omics Characterization of the Spontaneous Mesenchymal–Epithelial Transition in the PMC42 Breast Cancer Cell Lines
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journal
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August 2019 |
Preclinical Study of Biofunctional Polymer-Coated Upconversion Nanoparticles
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journal
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April 2019 |
Combined inhibition of Aurora A and p21-activated kinase 1 as a new treatment strategy in breast cancer
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journal
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June 2019 |
Subtype-specific overexpression of the Rac-GEF P-REX1 in breast cancer is associated with promoter hypomethylation
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journal
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September 2014 |
Multi-modal meta-analysis of cancer cell line omics profiles identifies ECHDC1 as a novel breast tumor suppressor
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posted_content
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January 2020 |
Gene isoforms as expression-based biomarkers predictive of drug response in vitro
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journal
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October 2017 |
Study design requirements for RNA sequencing-based breast cancer diagnostics
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journal
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February 2016 |
Drug sensitivity prediction framework using ensemble and multi-task learning
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journal
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November 2019 |
Multitask learning improves prediction of cancer drug sensitivity
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journal
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August 2016 |
Mapping phospho-catalytic dependencies of therapy-resistant tumours reveals actionable vulnerabilities
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journal
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June 2019 |
Prediction of anticancer molecules using hybrid model developed on molecules screened against NCI-60 cancer cell lines
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journal
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February 2016 |
Single-cell analyses of transcriptional heterogeneity during drug tolerance transition in cancer cells by RNA sequencing
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journal
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October 2014 |
In vitro human cell line models to predict clinical response to anticancer drugs
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journal
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March 2015 |
A Review of the Challenges of Using Biomedical Big Data for Economic Evaluations of Precision Medicine
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journal
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April 2019 |
Network-Based Isoform Quantification with RNA-Seq Data for Cancer Transcriptome Analysis
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journal
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December 2015 |
PharmacoDB: an integrative database for mining in vitro anticancer drug screening studies
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journal
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October 2017 |
Upregulation of Ets1 expression by NFATc2 and NFKB1/RELA promotes breast cancer cell invasiveness
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journal
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November 2018 |
Creating reproducible pharmacogenomic analysis pipelines
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journal
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September 2019 |
Estimating and accounting for tumor purity in the analysis of DNA methylation data from cancer studies
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journal
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January 2017 |
BET Bromodomain Proteins as Cancer Therapeutic Targets
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journal
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January 2016 |
Cellular and molecular determinants of all‐ trans retinoic acid sensitivity in breast cancer: Luminal phenotype and RAR α expression
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journal
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April 2015 |
GRcalculator: an online tool for calculating and mining dose–response data
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journal
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October 2017 |
Differential co-expression-based detection of conditional relationships in transcriptional data: comparative analysis and application to breast cancer
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journal
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November 2019 |
Differentiation-state plasticity is a targetable resistance mechanism in basal-like breast cancer
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journal
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September 2018 |
Single sample scoring of molecular phenotypes
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journal
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November 2018 |
Guanylate-binding protein-1 is a potential new therapeutic target for triple-negative breast cancer
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journal
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November 2017 |
Inferences of individual drug responses across diverse cancer types using a novel competing endogenous RNA network
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journal
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July 2018 |
SQUID: transcriptomic structural variation detection from RNA-seq
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journal
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April 2018 |
Circular RNAs are long-lived and display only minimal early alterations in response to a growth factor
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journal
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December 2015 |
Low-Dose and Long-Term Olaparib Treatment Sensitizes MDA-MB-231 and SUM1315 Triple-Negative Breast Cancers Spheroids to Fractioned Radiotherapy
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journal
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December 2019 |
Comprehensive anticancer drug response prediction based on a simple cell line-drug complex network model
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journal
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January 2019 |
Improved anticancer drug response prediction in cell lines using matrix factorization with similarity regularization
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journal
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August 2017 |
Revisiting inconsistency in large pharmacogenomic studies
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journal
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January 2016 |
Network-based clustering for drug sensitivity prediction in cancer cell lines
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posted_content
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January 2019 |
A Hybrid Interpolation Weighted Collaborative Filtering Method for Anti-cancer Drug Response Prediction
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journal
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September 2018 |
Analysis of H3K4me3 and H3K27me3 bivalent promotors in HER2+ breast cancer cell lines reveals variations depending on estrogen receptor status and significantly correlates with gene expression
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journal
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July 2020 |
Network-based approach to identify principal isoforms among four cancer types
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journal
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January 2019 |
Methods, Tools and Current Perspectives in Proteogenomics
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journal
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April 2017 |
Alternative empirical Bayes models for adjusting for batch effects in genomic studies
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journal
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July 2018 |
Detecting Transcriptomic Structural Variants in Heterogeneous Contexts via the Multiple Compatible Arrangements Problem
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posted_content
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January 2019 |
Predicting responses to platin chemotherapy agents with biochemically-inspired machine learning
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journal
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January 2019 |
Detecting transcriptomic structural variants in heterogeneous contexts via the Multiple Compatible Arrangements Problem
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journal
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May 2020 |
A normalized drug response metric improves accuracy and consistency of anticancer drug sensitivity quantification in cell-based screening
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journal
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January 2020 |
Activity of distinct growth factor receptor network components in breast tumors uncovers two biologically relevant subtypes
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journal
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April 2017 |
GenVisR: Genomic Visualizations in R
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journal
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June 2016 |
Deregulating MYC in a model of HER2+ breast cancer mimics human intertumoral heterogeneity
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journal
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November 2019 |
Identification of selective cytotoxic and synthetic lethal drug responses in triple negative breast cancer cells
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journal
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May 2016 |
SQUID: Transcriptomic Structural Variation Detection from RNA-seq
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journal
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September 2017 |
Overexpression and alternative splicing of NF-YA in breast cancer
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journal
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September 2019 |
FORESEE : a tool for the systematic comparison of translational drug response modeling pipelines
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text
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January 2019 |
A negative feedback loop between Insulin-like Growth Factor signaling and the lncRNA SNHG7 tightly regulates transcript levels and proliferation
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journal
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January 2019 |
FORESEE: a tool for the systematic comparison of translational drug response modeling pipelines
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journal
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March 2019 |
GenVisR: Genomic Visualizations in R
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journal
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March 2016 |
Creating reproducible pharmacogenomic analysis pipelines
|
journal
|
April 2019 |
Revisiting inconsistency in large pharmacogenomic studies
|
journal
|
January 2016 |
Detecting Transcriptomic Structural Variants in Heterogeneous Contexts via the Multiple Compatible Arrangements Problem
|
text
|
January 2019 |
Predicting Outcomes of Hormone and Chemotherapy in the Molecular Taxonomy of Breast Cancer International Consortium (METABRIC) Study by Biochemically-inspired Machine Learning
|
journal
|
January 2016 |
FORESEE: a tool for the systematic comparison of translational drug response modeling pipelines
|
posted_content
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October 2018 |
Multi-view kernel completion
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journal
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December 2016 |
Microenvironment-Mediated Mechanisms of Resistance to HER2 Inhibitors Differ between HER2+ Breast Cancer Subtypes
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journal
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March 2018 |
Anti-cancer Drug Response Prediction Using Neighbor-Based Collaborative Filtering with Global Effect Removal
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journal
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December 2018 |
Genetic Interaction-Based Biomarkers Identification for Drug Resistance and Sensitivity in Cancer Cells
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journal
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September 2019 |
Diurnal suppression of EGFR signalling by glucocorticoids and implications for tumour progression and treatment
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journal
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October 2014 |
Author Correction: Gene isoforms as expression-based biomarkers predictive of drug response in vitro
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journal
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January 2018 |
Computational imaging reveals mitochondrial morphology as a biomarker of cancer phenotype and drug response
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journal
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September 2016 |
A pathway-centric view of spatial proximity in the 3D nucleome across cell lines
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journal
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December 2016 |
Computational models for predicting drug responses in cancer research
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journal
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July 2016 |
A thesaurus of genetic variation for interrogation of repetitive genomic regions
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journal
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March 2015 |
Proteomic Analysis Defines Kinase Taxonomies Specific for Subtypes of Breast Cancer
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posted_content
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September 2017 |
CaDrA: A computational framework for performing candidate driver analyses using binary genomic features
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journal
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November 2017 |
Higher-order partial least squares for predicting gene expression levels from chromatin states
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conference
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November 2017 |
AICM: A Genuine Framework for Correcting Inconsistency Between Large Pharmacogenomics Datasets
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conference
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November 2018 |
Adaptive Multiview Nonnegative Matrix Factorization Algorithm for Integration of Multimodal Biomedical Data
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journal
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January 2017 |
Molecular fingerprinting catches responders to therapeutic agents
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journal
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January 2013 |
Unraveling heterogeneous susceptibility and the evolution of breast cancer using a systems biology approach
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journal
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February 2015 |
Erratum to: Modeling precision treatment of breast cancer
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journal
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May 2015 |
An Efficient Method for Identifying Gene Fusions by Targeted RNA Sequencing from Fresh Frozen and FFPE Samples
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journal
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July 2015 |
Comparison of the Prognostic Utility of the Diverse Molecular Data among lncRNA, DNA Methylation, microRNA, and mRNA across Five Human Cancers
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journal
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November 2015 |
A preclinical evaluation of the MEK inhibitor refametinib in HER2-positive breast cancer cell lines including those with acquired resistance to trastuzumab or lapatinib
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journal
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July 2017 |
Epithelial to mesenchymal transition is associated with rapamycin resistance
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journal
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April 2015 |
Identifying anti-cancer drug response related genes using an integrative analysis of transcriptomic and genomic variations with cell line-based drug perturbations
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journal
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January 2016 |
The Cure: Design and Evaluation of a Crowdsourcing Game for Gene Selection for Breast Cancer Survival Prediction
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journal
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July 2014 |
A Network-Based Model of Oncogenic Collaboration for Prediction of Drug Sensitivity
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journal
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December 2015 |
Identification of Prognostic Candidate Genes in Breast Cancer by Integrated Bioinformatic Analysis
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journal
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August 2019 |
Mining the Breast Cancer Proteome for Predictors of Drug Sensitivity
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journal
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January 2015 |
Network-based Isoform Quantification with RNA-Seq Data for Cancer Transcriptome Analysis
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text
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January 2014 |
A bayesian tensor factorization algorithm to predict drug response in cancer cell lines
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text
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January 2019 |