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Title: Ontobee: A linked ontology data server to support ontology term dereferencing, linkage, query and integration

Journal Article · · Nucleic Acids Research
DOI:https://doi.org/10.1093/nar/gkw918· OSTI ID:1625557
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  1. Univ. of Michigan Medical School, Ann Arbor, MI (United States)
  2. Univ. of Pennsylvania Perelman School of Medicine, Philadelphia, PA (United States)
  3. Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
  4. European Bioinformatics Inst., Cambridge (United Kingdom). European Molecular Biology Lab. (EMBL)
  5. Univ. at Buffalo, NY (United States)

Linked Data (LD) aims to achieve interconnected data by representing entities using Unified Resource Identifiers (URIs), and sharing information using Resource Description Frameworks (RDFs) and HTTP. Ontologies, which logically represent entities and relations in specific domains, are the basis of LD. Ontobee (http://www.ontobee.org/) is a linked ontology data server that stores ontology information using RDF triple store technology and supports query, visualization and linkage of ontology terms. Ontobee is also the default linked data server for publishing and browsing biomedical ontologies in the Open Biological Ontology (OBO) Foundry (http://obofoundry.org) library. Ontobee currently hosts more than 180 ontologies (including 131 OBO Foundry Library ontologies) with over four million terms. Ontobee provides a user-friendly web interface for querying and visualizing the details and hierarchy of a specific ontology term. Using the eXtensible Stylesheet Language Transformation (XSLT) technology, Ontobee is able to dereference a single ontology term URI, and then output RDF/eXtensible Markup Language (XML) for computer processing or display the HTML information on a web browser for human users. Statistics and detailed information are generated and displayed for each ontology listed in Ontobee. In addition, a SPARQL web interface is provided for custom advanced SPARQL queries of one or multiple ontologies.

Research Organization:
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
Sponsoring Organization:
USDOE Office of Science (SC)
Grant/Contract Number:
AC02-05CH11231; (NIAID) [R01AI081062]
OSTI ID:
1625557
Journal Information:
Nucleic Acids Research, Vol. 45, Issue D1; ISSN 0305-1048
Publisher:
Oxford University PressCopyright Statement
Country of Publication:
United States
Language:
English
Citation Metrics:
Cited by: 56 works
Citation information provided by
Web of Science

References (11)

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Cited By (22)

Harnessing the Power of Unified Metadata in an Ontology Repository: The Case of AgroPortal journal August 2018
Evaluation of ontology structural metrics based on public repository data journal February 2019
MCO: towards an ontology and unified vocabulary for a framework-based annotation of microbial growth conditions journal August 2018
queryMed: Semantic Web functions for linking pharmacological and medical knowledge to data journal January 2019
AgBioData consortium recommendations for sustainable genomics and genetics databases for agriculture journal January 2018
ONS: an ontology for a standardized description of interventions and observational studies in nutrition journal April 2018
ODAE: Ontology-based systematic representation and analysis of drug adverse events and its usage in study of adverse events given different patient age and disease conditions journal May 2019
The eXtensible ontology development (XOD) principles and tool implementation to support ontology interoperability journal January 2018
OHMI: the ontology of host-microbiome interactions journal December 2019
ClinEpiDB: an open-access clinical epidemiology database resource encouraging online exploration of complex studies journal January 2019
Scientist and data architect collaborate to curate and archive an inner ear electrophysiology data collection journal October 2019
A reusable tree-based web-visualization to browse EDAM ontology, and contribute to it. journal July 2018
Identifying Principles for the Construction of an Ontology-Based Knowledge Base: A Case Study Approach journal January 2018
String of PURLs – frugal migration and maintenance of persistent identifiers journal June 2020
Myo-REG: A Portal for Signaling Interactions in Muscle Regeneration journal September 2019
AgroPortal: A vocabulary and ontology repository for agronomy journal January 2018
SIFR annotator: ontology-based semantic annotation of French biomedical text and clinical notes journal November 2018
OSCI: standardized stem cell ontology representation and use cases for stem cell investigation journal April 2019
VIO: ontology classification and study of vaccine responses given various experimental and analytical conditions journal December 2019
ClinEpiDB: an open-access clinical epidemiology database resource encouraging online exploration of complex studies journal November 2019
Knowledge-based biomedical Data Science journal December 2017
Extracting Domain-specific Concepts from Large-scale Linked Open Data text January 2021

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