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BioMart Central Portal: an open database network for the biological community

Journal Article · · Database
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  1. Ontario Inst.e for Cancer Research, Toronto, ON (Canada); DOE/OSTI
  2. Univ. of California, Los Angeles, CA (United States). School of Dentistry. Dental Research Inst.
  3. Centre National de la Recherche Scientifique (CNRS), Paris (France). Centre de Genetique Moleculaire
  4. Ontario Inst.e for Cancer Research, Toronto, ON (Canada)
  5. Medical Rresearch Council (MRC) Harwell, Oxfordshire (United Kingdom)
  6. Western General Hospital, Edinburgh, Scotland (United Kingdom). Inst. of Genetics and Molecular Medicine. Medical Research Council (MRC). Human Genetics Unit
  7. Queen Mary Univ. of London (United Kingdom). Barts Cancer Inst. Centre for Molecular Oncology and Imaging
  8. Wellcome Trust Genome Campus, Cambridge (United Kingdom). EMBL-European Bioinformatics Inst.
  9. Univ. of Chile, Blanco Enclada (Chile). Center for Genome Regulation. Center for Mathematical Modeling
  10. WEllcome Trust Sanger Inst., Cambridge (United Kingdom). Cancer Genome Project
  11. Kasuza DNA Research Inst., Chiba (Japan)
  12. USDOE Joint Genome Institute (JGI), Walnut Creek, CA (United States); Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Genomics Division
  13. Universitat Pompeu Fabra, Barcelona (Spain). Dept. of Experimental and Health Sciences. Research Unit on Biomedical Informatics
  14. Univ. of Cambridge (United Kingdom). Computer Lab.
  15. The Jackson Lab., Bar Harbor, ME (United States). Mouse Genomic Informatics Group
  16. Cold Spring Harbor Laboratory Cold Spring Harbor, NY (United States)
  17. Univ. of Manchester (United Kingdom). Faculty of Life Sciences
  18. Wellcome Trust Sanger Inst., Hinxton (United Kingdom)
  19. Univ. of Tokyo (Japan)
  20. Peking Univ., Beijing (China). College of Life Sciences. State Key Lab. of protein and Plant Gene Research. Center for Bioinformatics
  21. Wellcome Trust Genome Campus, Cambridge (United Kingdom). EMBL-European Bioinformatics Inst. VectorBase
  22. Wellcome Trust Genome Campus, Cambridge (United Kingdom). EMBL-European Bioinformatics Inst. HUGO Gene Nomenclature Committee (HGNC)
  23. Institute National de la Recherche Agronomique (INRA), St-Gilles (France). Sigenae
  24. Wellcome Trust Sanger Inst., Cambridge (United Kingdom). Wellcome Trust Genome Campus
  25. Univ. of Rennes (France). Inserm U625
  26. Wellcome Trust Sanger Inst., Cambridge (United Kingdom).Wellcome Trust Genome Campus. Cancer Genome Project
  27. International Potato Center (CIP), Lima (Peru)
  28. Wellcome Trust Sanger Inst., Hinxton (United Kingdom).Wellcome Trust Genome Campus.
  29. Cold Spring Harbor Laboratory Cold Spring Harbor, NY (United States); Eagle Genomics Ltd., Cambridge (United Kingdom). Babraham Research Campus
BioMart Central Portal is a first of its kind, community-driven effort to provide unified access to dozens of biological databases spanning genomics, proteomics, model organisms, cancer data, ontology information and more. Anybody can contribute an independently maintained resource to the Central Portal, allowing it to be exposed to and shared with the research community, and linking it with the other resources in the portal. Users can take advantage of the common interface to quickly utilize different sources without learning a new system for each. The system also simplifies cross-database searches that might otherwise require several complicated steps. Several integrated tools streamline common tasks, such as converting between ID formats and retrieving sequences. The combination of a wide variety of databases, an easy-to-use interface, robust programmatic access and the array of tools make Central Portal a one-stop shop for biological data querying. Here, we describe the structure of Central Portal and show example queries to demonstrate its capabilities. Database URL: http://central.biomart.org.
Research Organization:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). National Energy Research Scientific Computing Center (NERSC)
Sponsoring Organization:
USDOE Office of Science (SC), Biological and Environmental Research (BER). Biological Systems Science Division
Grant/Contract Number:
AC02-05CH11231
OSTI ID:
1625302
Journal Information:
Database, Journal Name: Database Vol. 2011; ISSN 1758-0463
Publisher:
Oxford University Press - International Society for BiocurationCopyright Statement
Country of Publication:
United States
Language:
English

References (19)

The HUGO Gene Nomenclature Committee (HGNC) journal October 2001
GermOnline 4.0 is a genomics gateway for germline development, meiosis and the mitotic cell cycle journal December 2010
SigReannot-mart: a query environment for expression microarray probe re-annotations journal September 2011
BioMart as an integration solution for the International Knockout Mouse Consortium journal September 2011
The InterPro BioMart: federated query and web service access to the InterPro Resource journal July 2011
Integrative Cancer Genomics (IntOGen) in Biomart journal September 2011
KEGG: Kyoto Encyclopedia of Genes and Genomes journal January 2000
PepSeeker: a database of proteome peptide identifications for investigating fragmentation patterns journal January 2006
From genomics to chemical genomics: new developments in KEGG journal January 2006
VectorBase: a home for invertebrate vectors of human pathogens journal January 2007
The vertebrate genome annotation (Vega) database journal December 2007
BioMart Central Portal—unified access to biological data journal May 2009
EMMA--mouse mutant resources for the international scientific community journal September 2009
WormBase: a comprehensive resource for nematode research journal November 2009
The Proteomics Identifications database: 2010 update journal November 2009
ParameciumDB in 2011: new tools and new data for functional and comparative genomics of the model ciliate Paramecium tetraurelia journal October 2010
BioMart – biological queries made easy journal January 2009
KEGG for representation and analysis of molecular networks involving diseases and drugs journal October 2009
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo journal January 2011

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A catalogue of Bilaterian-specific genes – their function and expression profiles in early development journal April 2016
MicroRNA-mRNA networks define translatable molecular outcome phenotypes in osteosarcoma. journal January 2019
Transcriptome Responses to Combinations of Stresses in Arabidopsis journal February 2013
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Multi-omics Data Integration, Interpretation, and Its Application journal January 2020
AbsIDconvert: An absolute approach for converting genetic identifiers at different granularities journal September 2012
The KUPNetViz: a biological network viewer for multiple -omics datasets in kidney diseases journal July 2013
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Identification of genome-wide copy number variations among diverse pig breeds by array CGH journal January 2012
Uncovering adaptive evolution in the human lineage journal January 2014
OvMark: a user-friendly system for the identification of prognostic biomarkers in publically available ovarian cancer gene expression datasets journal January 2014
Remodeling Cildb, a popular database for cilia and links for ciliopathies journal November 2014
BreastMark: An Integrated Approach to Mining Publicly Available Transcriptomic Datasets Relating to Breast Cancer Outcome journal July 2013
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Analysis of Stop-Gain and Frameshift Variants in Human Innate Immunity Genes journal July 2014
A Minimal Connected Network of Transcription Factors Regulated in Human Tumors and Its Application to the Quest for Universal Cancer Biomarkers journal June 2012
Nrac, a Novel Nutritionally-Regulated Adipose and Cardiac-Enriched Gene journal September 2012
RTCGAToolbox: A New Tool for Exporting TCGA Firehose Data journal September 2014
Genome Wide Distributions and Functional Characterization of Copy Number Variations between Chinese and Western Pigs journal July 2015
Genome-Wide Detection of CNVs and Their Association with Meat Tenderness in Nelore Cattle journal June 2016
Extensive Association of Common Disease Variants with Regulatory Sequence journal November 2016
Age, gender and UV-exposition related effects on gene expression in in vivo aged short term cultivated human dermal fibroblasts journal May 2017
Genome scale transcriptional response diversity among ten ecotypes of Arabidopsis thaliana during heat stress journal January 2013
Human cancer databases (Review) journal October 2014
Master Regulators, Regulatory Networks, and Pathways of Glioblastoma Subtypes journal January 2014
Metabolic and Chaperone Gene Loss Marks the Origin of Animals: Evidence for Hsp104 and Hsp78 Sharing Mitochondrial Clients text January 2013
Additional file 2 of dbNSFP v4: a comprehensive database of transcript-specific functional predictions and annotations for human nonsynonymous and splice-site SNVs dataset January 2020
dbNSFP v2.0: A Database of Human Non-synonymous SNVs and Their Functional Predictions and Annotations journal July 2013
Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions journal July 2015
Crowdsourcing in proteomics: public resources lead to better experiments journal February 2013
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Ranking noncanonical 5′ splice site usage by genome-wide RNA-seq analysis and splicing reporter assays journal October 2018
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The Evolutionary Landscape of Alternative Splicing in Vertebrate Species journal December 2012
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BubbleGUM: automatic extraction of phenotype molecular signatures and comprehensive visualization of multiple Gene Set Enrichment Analyses journal October 2015
DAPPER: a data-mining resource for protein-protein interactions journal June 2015
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