Thermodynamic Coupling Function Analysis of Allosteric Mechanisms in the Human Dopamine Transporter
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January 2018 |
Neurotransmitter transporters: molecular function of important drug targets
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July 2006 |
X-ray structures of LeuT in substrate-free outward-open and apo inward-open states
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January 2012 |
Maximum likelihood estimation of aggregated Markov processes
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March 1997 |
Electrostatics of nanosystems: Application to microtubules and the ribosome
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August 2001 |
Serotonin transporter–ibogaine complexes illuminate mechanisms of inhibition and transport
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April 2019 |
Overview of the CCP 4 suite and current developments
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March 2011 |
Simple Allosteric Model for Membrane Pumps
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August 1966 |
Monoamine transporters: structure, intrinsic dynamics and allosteric regulation
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July 2019 |
Scalable molecular dynamics with NAMD
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January 2005 |
Spontaneous Inward Opening of the Dopamine Transporter Is Triggered by PIP 2 -Regulated Dynamics of the N-Terminus
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August 2015 |
Transition metal ion FRET uncovers K+ regulation of a neurotransmitter/sodium symporter
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September 2016 |
Binding of an octylglucoside detergent molecule in the second substrate (S2) site of LeuT establishes an inhibitor-bound conformation
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March 2009 |
High-Affinity Adaptors for Switchable Recognition of Histidine-Tagged Proteins
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July 2005 |
How structural elements evolving from bacterial to human SLC6 transporters enabled new functional properties
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March 2018 |
SLC6 Neurotransmitter Transporters: Structure, Function, and Regulation
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July 2011 |
Single-molecule analysis of ligand efficacy in β2AR–G-protein activation
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June 2017 |
The use of LeuT as a model in elucidating binding sites for substrates and inhibitors in neurotransmitter transporters
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March 2015 |
Single-molecule imaging of non-equilibrium molecular ensembles on the millisecond timescale
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February 2016 |
Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters
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July 2005 |
A mechanism for intracellular release of Na+ by neurotransmitter/sodium symporters
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October 2014 |
Ion-Controlled Conformational Dynamics in the Outward-Open Transition from an Occluded State of LeuT
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September 2012 |
X-ray structures of Drosophila dopamine transporter in complex with nisoxetine and reboxetine
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May 2015 |
A Competitive Inhibitor Traps LeuT in an Open-to-Out Conformation
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December 2008 |
The Environment Shapes the Inner Vestibule of LeuT
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November 2016 |
Substrate-induced conformational dynamics of the dopamine transporter
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June 2019 |
Modeling and Dynamics of the Inward-Facing State of a Na+/Cl− Dependent Neurotransmitter Transporter Homologue
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August 2010 |
Conformational dynamics of ligand-dependent alternating access in LeuT
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April 2014 |
Conformational dynamics of the human serotonin transporter during substrate and drug binding
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April 2019 |
XDS
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January 2010 |
Allosteric Mechanisms of Molecular Machines at the Membrane: Transport by Sodium-Coupled Symporters
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February 2016 |
Mechanism of chloride interaction with neurotransmitter:sodium symporters
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August 2007 |
ACEMD: Accelerating Biomolecular Dynamics in the Microsecond Time Scale
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May 2009 |
The Mechanism of a Neurotransmitter:Sodium Symporter—Inward Release of Na+ and Substrate Is Triggered by Substrate in a Second Binding Site
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June 2008 |
Alternating access mechanisms of LeuT-fold transporters: trailblazing towards the promised energy landscapes
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August 2017 |
The solute carrier 6 family of transporters: The Solute Carrier Family 6
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August 2012 |
Comparative Protein Modelling by Satisfaction of Spatial Restraints
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December 1993 |
PROPKA3: Consistent Treatment of Internal and Surface Residues in Empirical p K a Predictions
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December 2010 |
Namdinator – automatic molecular dynamics flexible fitting of structural models into cryo-EM and crystallography experimental maps
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June 2019 |
X-ray structure of dopamine transporter elucidates antidepressant mechanism
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September 2013 |
A partially-open inward-facing intermediate conformation of LeuT is associated with Na+ release and substrate transport
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January 2018 |
A structural model of the human serotonin transporter in an outward-occluded state
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June 2019 |
Features and development of Coot
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March 2010 |
X-ray structures and mechanism of the human serotonin transporter
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April 2016 |
Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homologue
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April 2011 |
Single-molecule dynamics of gating in a neurotransmitter transporter homologue
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May 2010 |
Monitoring the function of membrane transport proteins in detergent-solubilized form
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February 2007 |
Mechanism for alternating access in neurotransmitter transporters
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July 2008 |
Conformational dynamics of a neurotransmitter:sodium symporter in a lipid bilayer
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February 2017 |
PHENIX: a comprehensive Python-based system for macromolecular structure solution
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January 2010 |
Glutamate and monoamine transporters: new visions of form and function
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June 2007 |
Substrate-modulated unwinding of transmembrane helices in the NSS transporter LeuT
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May 2018 |
How LeuT shapes our understanding of the mechanisms of sodium-coupled neurotransmitter transporters: Role of LeuT in understanding neurotransmitter transporters
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August 2013 |
A smooth particle mesh Ewald method
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November 1995 |
A conserved leucine occupies the empty substrate site of LeuT in the Na+-free return state
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May 2016 |
Complete Mapping of Substrate Translocation Highlights the Role of LeuT N-terminal Segment in Regulating Transport Cycle
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October 2014 |
The allosteric mechanism of substrate-specific transport in SLC6 is mediated by a volumetric sensor
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July 2019 |
VMD: Visual molecular dynamics
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February 1996 |
Phaser crystallographic software
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July 2007 |
A Markov State-based Quantitative Kinetic Model of Sodium Release from the Dopamine Transporter
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January 2017 |
Identification of slow molecular order parameters for Markov model construction
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July 2013 |
The effect of acidic pH on the adsorption and lytic activity of the peptides Polybia-MP1 and its histidine-containing analog in anionic lipid membrane: a biophysical study by molecular dynamics and spectroscopy
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April 2021 |
Spontaneous Inward Opening of the Dopamine Transporter is Triggered by PIP2-Regulated Dynamics of the N-Terminus
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February 2016 |
Stepwise gating of the Sec61 protein-conducting channel by Sec63 and Sec62
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January 2021 |
Structural and functional characterization of an achromatopsia-associated mutation in a phototransduction channel
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March 2022 |
Substrate-induced Unlocking of the Inner Gate Determines the Catalytic Efficiency of a Neurotransmitter:Sodium Symporter
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September 2015 |
Two Na + Sites Control Conformational Change in a Neurotransmitter Transporter Homolog
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November 2015 |
Conformational Dynamics on the Extracellular Side of LeuT Controlled by Na + and K + Ions and the Protonation State of Glu 290
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July 2016 |
The Cytoplasmic Substrate Permeation Pathway of Serotonin Transporter
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September 2006 |
A Functional-Phylogenetic Classification System for Transmembrane Solute Transporters
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June 2000 |
Negative Regulation of Dopamine Transporter Endocytosis by Membrane-Proximal N-Terminal Residues
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February 2009 |
PHENIX: a comprehensive Python-based system for macromolecular structure solution.
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January 2010 |
Identification of slow molecular order parameters for Markov model construction
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January 2013 |