High-throughput screening for discovery of benchtop separations systems for selected rare earth elements

Nelson, Joshua J. M.; Cheisson, Thibault; Rugh, Haley J.; Gau, Michael R.; Carroll, Patrick J.; Schelter, Eric J.

doi:10.1038/s42004-019-0253-x

High-throughput screening for discovery of benchtop separations systems for selected rare earth elements

Journal Article · Mon Jan 20 00:00:00 EST 2020 · Communications Chemistry

DOI:https://doi.org/10.1038/s42004-019-0253-x· OSTI ID:1619732

; ; ; Gau, Michael R.; Carroll, Patrick J.;

Abstract

Rare earth (RE) elements (scandium, yttrium, and the lanthanides) are critical for their role in sustainable energy technologies. Problems with their supply chain have motivated research to improve separations methods to recycle these elements from end of life technology. Toward this goal, we report the synthesis and characterization of the ligand tris[(1-hydroxy-2-oxo-1,2-dihydropyridine-3-carboxamido)ethyl]amine, H ₃ 1·TFA (TFA = trifluoroacetic acid), and complexes 1·RE (RE = La, Nd, Dy). A high-throughput experimentation (HTE) screen was developed to quantitatively determine the precipitation of 1·RE as a function of pH as well as equivalents of H ₃ 1·TFA. This method rapidly determines optimal conditions for the separation of RE mixtures, while minimizing materials consumption. The HTE-predicted conditions are used to achieve the lab-scale separation of Nd/Dy ( SF _Nd/Dy = 213 ± 34) and La/Nd ( SF _La/Nd = 16.2 ± 0.2) mixtures in acidic aqueous media.

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Research Organization:: Energy Frontier Research Centers (EFRC) (United States). Center for Actinide Science & Technology (CAST); Florida State Univ., Tallahassee, FL (United States); Univ. of Pennsylvania, Philadelphia, PA (United States)

Sponsoring Organization:: USDOE Office of Science (SC), Basic Energy Sciences (BES)

Grant/Contract Number:: SC0016568; SC0017259

OSTI ID:: 1619732

Alternate ID(s):: OSTI ID: 1767685

Journal Information:: Communications Chemistry, Journal Name: Communications Chemistry Journal Issue: 1 Vol. 3; ISSN 2399-3669

Publisher:: Springer NatureCopyright Statement

Country of Publication:: United Kingdom

Language:: English

References (45)

An Operationally Simple Method for Separating the Rare-Earth Elements Neodymium and Dysprosium Bogart, Justin A.; Lippincott, Connor A.; Carroll, Patrick J. Angewandte Chemie International Edition, Vol. 54, Issue 28 https://doi.org/10.1002/anie.201501659	journal	May 2015
High-throughput screening techniques for rapid PEG-based precipitation of IgG4 mAb from clarified cell culture supernatant Knevelman, Carol; Davies, Jim; Allen, Lee Biotechnology Progress, Vol. 26, Issue 3 https://doi.org/10.1002/btpr.357	journal	December 2009
Application of a High-Throughput Screening Procedure with PEG-Induced Precipitation to Compare Relative Protein Solubility During Formulation Development with IgG1 Monoclonal Antibodies Gibson, Todd J.; Mccarty, Katie; McFadyen, Iain J. Journal of Pharmaceutical Sciences, Vol. 100, Issue 3 https://doi.org/10.1002/jps.22350	journal	March 2011
Progress in the extraction and separation of rare earths and related metals with novel extractants: A review Kuang, ShengTing; Liao, WuPing Science China Technological Sciences, Vol. 61, Issue 9 https://doi.org/10.1007/s11431-018-9295-0	journal	July 2018
Fractional extraction of the lanthanides as their di-alkyl orthophosphates Peppard, D. F.; Mason, G. W.; Maier, J. L. Journal of Inorganic and Nuclear Chemistry, Vol. 4, Issue 5-6 https://doi.org/10.1016/0022-1902(57)80016-5	journal	January 1957
Recycling of Rare Earths from Scrap Tanaka, Mikiya; Oki, Tatsuya; Koyama, Kazuya Handbook on the Physics and Chemistry of Rare Earths https://doi.org/10.1016/B978-0-444-59536-2.00002-7	book	January 2013
Rare Earth Elements: Industrial Applications and Economic Dependency of Europe Charalampides, Georgios; Vatalis, Konstantinos I.; Apostoplos, Baklavaridis Procedia Economics and Finance, Vol. 24 https://doi.org/10.1016/S2212-5671(15)00630-9	journal	January 2015
High throughput solubility determination with application to selection of compounds for fragment screening Colclough, Nicola; Hunter, Alison; Kenny, Peter W. Bioorganic & Medicinal Chemistry, Vol. 16, Issue 13 https://doi.org/10.1016/j.bmc.2008.05.021	journal	July 2008
Coordination chemistry of f-block metal ions with ligands bearing bio-relevant functional groups Götzke, Linda; Schaper, Gerrit; März, Juliane Coordination Chemistry Reviews, Vol. 386 https://doi.org/10.1016/j.ccr.2019.01.006	journal	May 2019
Microcolumn lanthanide separation using bis-(2-ethylhexyl) phosphoric acid functionalized ordered mesoporous carbon materials Bertelsen, Erin R.; Deodhar, Gauri; Kluherz, Kyle T. Journal of Chromatography A, Vol. 1595 https://doi.org/10.1016/j.chroma.2019.02.057	journal	June 2019
The solvent extraction of rare earth elements from nitrate media with novel polyamides containing malonamide groups Tyumentsev, Mikhail S.; Foreman, Mark R. St. J.; Ekberg, Christian Hydrometallurgy, Vol. 164 https://doi.org/10.1016/j.hydromet.2016.05.007	journal	September 2016
Interactions between trivalent rare earth oxides and mixed [Hbet][Tf2N]:H2O systems in the development of a one-step process for the separation of light from heavy rare earth elements Schaeffer, Nicolas; Grimes, Sue; Cheeseman, Chris Inorganica Chimica Acta, Vol. 439 https://doi.org/10.1016/j.ica.2015.09.015	journal	January 2016
Recycling of rare earths: a critical review Binnemans, Koen; Jones, Peter Tom; Blanpain, Bart Journal of Cleaner Production, Vol. 51 https://doi.org/10.1016/j.jclepro.2012.12.037	journal	July 2013
Rare-earth elements in the circular economy: The case of yttrium Favot, Marinella; Massarutto, Antonio Journal of Environmental Management, Vol. 240 https://doi.org/10.1016/j.jenvman.2019.04.002	journal	June 2019
Rare earths supply chains: Current status, constraints and opportunities Golev, Artem; Scott, Margaretha; Erskine, Peter D. Resources Policy, Vol. 41 https://doi.org/10.1016/j.resourpol.2014.03.004	journal	September 2014
Rare-earth elements market: A historical and financial perspective Fernandez, Viviana Resources Policy, Vol. 53 https://doi.org/10.1016/j.resourpol.2017.05.010	journal	September 2017
Structure and patterns of the international rare earths trade: A complex network analysis Hou, Wenyu; Liu, Huifang; Wang, Hui Resources Policy, Vol. 55 https://doi.org/10.1016/j.resourpol.2017.11.008	journal	March 2018
The Evolution of Chemical High-Throughput Experimentation To Address Challenging Problems in Pharmaceutical Synthesis Krska, Shane W.; DiRocco, Daniel A.; Dreher, Spencer D. Accounts of Chemical Research, Vol. 50, Issue 12 https://doi.org/10.1021/acs.accounts.7b00428	journal	November 2017
Hydroxypyridinone Journey into Metal Chelation Cilibrizzi, Agostino; Abbate, Vincenzo; Chen, Yu-Lin Chemical Reviews, Vol. 118, Issue 16 https://doi.org/10.1021/acs.chemrev.8b00254	journal	July 2018
Selective Extraction of Rare Earth Elements from Permanent Magnet Scraps with Membrane Solvent Extraction Kim, Daejin; Powell, Lawrence E.; Delmau, Lætitia H. Environmental Science & Technology, Vol. 49, Issue 16 https://doi.org/10.1021/acs.est.5b01306	journal	July 2015
Sustainable Inorganic Chemistry: Metal Separations for Recycling Nelson, Joshua J. M.; Schelter, Eric J. Inorganic Chemistry, Vol. 58, Issue 2 https://doi.org/10.1021/acs.inorgchem.8b01871	journal	January 2019
Selective Crystallization of Phosphoester Coordination Polymer for the Separation of Neodymium and Dysprosium: A Thermodynamic Approach Tasaki-Handa, Yuiko; Abe, Yukie; Ooi, Kenta The Journal of Physical Chemistry B, Vol. 120, Issue 49 https://doi.org/10.1021/acs.jpcb.6b09450	journal	November 2016
The Evolution of High-Throughput Experimentation in Pharmaceutical Development and Perspectives on the Future Mennen, Steven M.; Alhambra, Carolina; Allen, C. Liana Organic Process Research & Development, Vol. 23, Issue 6 https://doi.org/10.1021/acs.oprd.9b00140	journal	May 2019
Practical High-Throughput Experimentation for Chemists Shevlin, Michael ACS Medicinal Chemistry Letters, Vol. 8, Issue 6 https://doi.org/10.1021/acsmedchemlett.7b00165	journal	May 2017
Phosphoryl-Ligand Adducts of Rare Earth-TriNOx Complexes: Systematic Studies and Implications for Separations Chemistry Cheisson, Thibault; Cole, Bren E.; Manor, Brian C. ACS Sustainable Chemistry & Engineering, Vol. 7, Issue 5 https://doi.org/10.1021/acssuschemeng.8b05638	journal	January 2019
Gd−Hydroxypyridinone (HOPO)-Based High-Relaxivity Magnetic Resonance Imaging (MRI) Contrast Agents Datta, Ankona; Raymond, Kenneth N. Accounts of Chemical Research, Vol. 42, Issue 7 https://doi.org/10.1021/ar800250h	journal	July 2009
1,2-Hydroxypyridonates as Contrast Agents for Magnetic Resonance Imaging: TREN-1,2-HOPO Jocher, Christoph J.; Moore, Evan G.; Xu, Jide Inorganic Chemistry, Vol. 46, Issue 22 https://doi.org/10.1021/ic700985j	journal	October 2007
Gadolinium complex of tris[(3-hydroxy-1-methyl- 2-oxo-1,2-didehydropyridine-4-carboxamido)ethyl]-amine: A New Class of gadolinium magnetic resonance relaxation agents Xu, Jide; Franklin, Sonya J.; Whisenhunt, Donald W. Journal of the American Chemical Society, Vol. 117, Issue 27, p. 7245-7246 https://doi.org/10.1021/ja00132a025	journal	July 1995
Synergistic Effect between Bifunctional Ionic Liquids and a Molecular Extractant for Lanthanide Separation Sun, Xiaoqi; Waters, Kristian E. ACS Sustainable Chemistry & Engineering, Vol. 2, Issue 12 https://doi.org/10.1021/sc500493d	journal	November 2014
Rare earth separations by selective borate crystallization Yin, Xuemiao; Wang, Yaxing; Bai, Xiaojing Nature Communications, Vol. 8, Issue 1 https://doi.org/10.1038/ncomms14438	journal	March 2017
Evaluating the potential of chelation therapy to prevent and treat gadolinium deposition from MRI contrast agents Rees, Julian A.; Deblonde, Gauthier J. -P.; An, Dahlia D. Scientific Reports, Vol. 8, Issue 1 https://doi.org/10.1038/s41598-018-22511-6	journal	March 2018
The power and accessibility of high-throughput methods for catalysis research Allen, C. Liana; Leitch, David C.; Anson, Michael S. Nature Catalysis, Vol. 2, Issue 1 https://doi.org/10.1038/s41929-018-0220-4	journal	January 2019
Photochemical recycling of europium from Eu/Y mixtures in red lamp phosphor waste streams Van den Bogaert, Bart; Havaux, Daphné; Binnemans, Koen Green Chemistry, Vol. 17, Issue 4 https://doi.org/10.1039/C4GC02140A	journal	January 2015
Extraction and separation of neodymium and dysprosium from used NdFeB magnets: an application of ionic liquids in solvent extraction towards the recycling of magnets Riaño, Sofía; Binnemans, Koen Green Chemistry, Vol. 17, Issue 5 https://doi.org/10.1039/C5GC00230C	journal	January 2015
Efficient separation of rare earths recovered by a supported ionic liquid from bauxite residue leachate Avdibegović, Dženita; Regadío, Mercedes; Binnemans, Koen RSC Advances, Vol. 8, Issue 22 https://doi.org/10.1039/C7RA13402A	journal	January 2018
A molecular basis to rare earth separations for recycling: tuning the TriNOx ligand properties for improved performance Cole, Bren E.; Falcones, Ingemar B.; Cheisson, Thibault Chemical Communications, Vol. 54, Issue 73 https://doi.org/10.1039/C8CC04409K	journal	January 2018
Is hydroxypyridonate 3,4,3-LI(1,2-HOPO) a good competitor of fetuin for uranyl metabolism? Younes, Ali; Creff, Gaëlle; Beccia, Maria Rosa Metallomics, Vol. 11, Issue 2 https://doi.org/10.1039/C8MT00272J	journal	January 2019
Ionic liquids tethered to a preorganised 1,2-diamide motif for extraction of lanthanides Boyd, Robert; Jin, Lili; Nockemann, Peter Green Chemistry, Vol. 21, Issue 10 https://doi.org/10.1039/C9GC00089E	journal	January 2019
Breaking the 1,2-HOPO barrier with a cyclen backbone for more efficient sensitization of Eu( iii ) luminescence and unprecedented two-photon excitation properties Dai, Lixiong; Lo, Wai-Sum; Gu, Yanjuan Chemical Science, Vol. 10, Issue 17 https://doi.org/10.1039/C9SC00244H	journal	January 2019
Accomplishing simple, solubility-based separations of rare earth elements with complexes bearing size-sensitive molecular apertures Bogart, Justin A.; Cole, Bren E.; Boreen, Michael A. Proceedings of the National Academy of Sciences, Vol. 113, Issue 52 https://doi.org/10.1073/pnas.1612628113	journal	December 2016
Extraction Chromatography Versus Solvent Extraction: How Similar are They? Philip Horwitz, E.; McAlister, Daniel R.; Dietz, Mark L. Separation Science and Technology, Vol. 41, Issue 10 https://doi.org/10.1080/01496390600742849	journal	June 2006
Extraction of rare Earth Metals with 2-Ethylhexyl Phosphonic acid Mono-2-Ethylhexyl Ester in the Presence of Diethylenetriaminepentaacetic acid in Aqueous Phase Kubota, Fukiko; Goto, Masahiro; Nakashio, Fumiyuki Solvent Extraction and Ion Exchange, Vol. 11, Issue 3 https://doi.org/10.1080/07366299308918165	journal	January 1993
Biomimetic Actinide Chelators: an Update on the Preclinical Development of the Orally Active Hydroxypyridonate Decorporation Agents 3,4,3-Li(1,2-Hopo) and 5-Lio(Me-3,2-Hopo) Abergel, Rebecca J.; Durbin, Patricia W.; Kullgren, Birgitta Health Physics, Vol. 99, Issue 3 https://doi.org/10.1097/HP.0b013e3181c21273	journal	January 2010
Iterative screen optimization maximizes the efficiency of macromolecular crystallization Jones, Harrison G.; Wrapp, Daniel; Gilman, Morgan S. A. Acta Crystallographica Section F Structural Biology Communications, Vol. 75, Issue 2 https://doi.org/10.1107/S2053230X18017338	journal	January 2019
Rare earth elements: Mendeleev’s bane, modern marvels Cheisson, Thibault; Schelter, Eric J. Science, Vol. 363, Issue 6426 https://doi.org/10.1126/science.aau7628	journal	January 2019

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