New In Situ Imaging and Measurement Technologies for Biological Systems (Brochure)

Program Document · Fri Aug 01 04:00:00 EDT 2014

OSTI ID:1616685

Srivastava, Prem C. ^[1]; Anderson, R. Todd ^[1]

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1. Dept. of Energy (DOE), Washington DC (United States). Office of Science. Office of Biological and Environmental Research. Biological Systems Science Division

The U.S. Department of Energy’s (DOE) Office of Biological and Environmental Research (BER) supports fundamental research to advance a predictive understanding of complex biological and environmental systems relevant to DOE’s missions in energy and the environment. Starting with the genetic potential encoded by organisms’ genomes, BER scientists seek to define the principles guiding translation of the genetic code into functional proteins and the metabolic and regulatory networks underlying plant and microbial systems. Concurrent with this research is a need for enabling technologies to place understanding of gene expression, regulation, and function into the spatiotemporal context of whole-cell environments. Imaging and measurement technologies that can resolve multiple key metabolic processes over time within or among cells will act as a crucial bridge toward linking molecular-scale information to whole-cell, systems-level understanding. This brochure outlines the pilot projects at the DOE national laboratories and the investigators leading these efforts. This initial description of BER’s new effort serves as an informational resource for the evolving imaging and measurement technology program.

• Research Organization: USDOE Office of Science (SC) (United States)
• Sponsoring Organization: USDOE Office of Science (SC), Biological and Environmental Research (BER) (SC-23)
• OSTI ID: 1616685
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES