GeneBee-net: Internet-based server for analyzing biopolymers
- Small Scientific Manufacturing Enterprise, Moscow (Russian Federation); and others
This work describes a network server for searching databanks of biopolymer structures and performing other biocomputing procedures; it is available via direct Internet connection. Basic server procedures are dedicated to homology (similarity) search of sequence and 3D structure of proteins. The homologies found could be used to build multiple alignments, predict protein and RNA secondary structure, and construct phylogenetic trees. In addition to traditional methods of sequence similarity search, the authors propose {open_quotes}non-matrix{close_quotes} (correlational) search. An analogous approach is used to identify regions of similar tertiary structure of proteins. Algorithm concepts and usage examples are presented for new methods. Service logic is based upon interaction of a client program and server procedures. The client program allows the compilation of queries and the processing of results of an analysis.
- OSTI ID:
- 161602
- Journal Information:
- Biochemistry (Eaton), Vol. 60, Issue 8; Other Information: PBD: Aug 1995
- Country of Publication:
- United States
- Language:
- English
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