Skip to main content
U.S. Department of Energy
Office of Scientific and Technical Information

Structures of AAA protein translocase Bcs1 suggest translocation mechanism of a folded protein

Journal Article · · Nat. Struct. Mol. Biol.
Abstract not provided
Research Organization:
Advanced Photon Source (APS), Argonne National Laboratory (ANL), Argonne, IL (US)
Sponsoring Organization:
NIH
OSTI ID:
1605436
Journal Information:
Nat. Struct. Mol. Biol., Journal Name: Nat. Struct. Mol. Biol. Journal Issue: 02, 2020 Vol. 27
Country of Publication:
United States
Language:
ENGLISH

References (56)

Structure of the Cdc48 segregase in the act of unfolding an authentic substrate journal June 2019
Refinement of Macromolecular Structures by the Maximum-Likelihood Method journal May 1997
Structure of the Cytochrome b6f Complex of Oxygenic Photosynthesis: Tuning the Cavity journal November 2003
Crystal Structure of the Cytochrome bc 1 Complex from Bovine Heart Mitochondria journal July 1997
[20] Processing of X-ray diffraction data collected in oscillation mode book January 1997
Clinical spectrum of BCS1L Mitopathies and their underlying structural relationships journal December 2018
Structural Basis of Resistance to Anti-Cytochrome bc1 Complex Inhibitors: Implication for Drug Improvement journal February 2014
Cryo-EM structure of the essential ribosome assembly AAA-ATPase Rix7 journal January 2019
The GRACILE mutation introduced into Bcs1l causes postnatal complex III deficiency: A viable mouse model for mitochondrial hepatopathy journal December 2010
An improved assay for nanomole amounts of inorganic phosphate journal November 1979
Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding journal June 2019
Infantile mitochondrial encephalomyopathy with unusual phenotype caused by a novel BCS1L mutation in an isolated complex III-deficient patient journal February 2009
The CCP4 suite programs for protein crystallography journal September 1994
Substrate-engaged 26 S proteasome structures reveal mechanisms for ATP-hydrolysis–driven translocation journal October 2018
The AAA ATPase Vps4 binds ESCRT-III substrates through a repeating array of dipeptide-binding pockets journal November 2017
Structures and operating principles of the replisome journal January 2019
AAA+ superfamily ATPases: common structure-diverse function journal July 2001
Structure at 2.3 Å resolution of the cytochrome bc1 complex from the yeast Saccharomyces cerevisiae co-crystallized with an antibody Fv fragment journal June 2000
Measurement of protein using bicinchoninic acid journal October 1985
Mechanisms of Sec61/SecY-Mediated Protein Translocation Across Membranes journal June 2012
Mutational analysis of assembly and function of the iron-sulfur protein of the cytochromebc 1 complex inSaccharomyces cerevisiae journal June 1993
Late-Stage Maturation of the Rieske Fe/S Protein: Mzm1 Stabilizes Rip1 but Does Not Facilitate Its Translocation by the AAA ATPase Bcs1 journal August 2012
PHENIX : building new software for automated crystallographic structure determination journal October 2002
New tools for automated high-resolution cryo-EM structure determination in RELION-3 journal November 2018
Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104 journal June 2017
Bcs1p, an AAA-family member, is a chaperone for the assembly of the cytochrome bc1 complex journal October 1999
A Pathway of Protein Translocation in Mitochondria Mediated by the AAA-ATPase Bcs1 journal October 2011
Automatic local resolution-based sharpening of cryo-EM maps journal August 2019
Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome journal November 2018
Functional Analysis of Yeast bcs1 Mutants Highlights the Role of Bcs1p-Specific Amino Acids in the AAA Domain journal May 2009
Mitochondrial proteins: from biogenesis to functional networks journal January 2019
Missense Mutations in the BCS1L Gene as a Cause of the Björnstad Syndrome journal February 2007
BCS1, a novel gene required for the expression of functional Rieske iron-sulfur protein in Saccharomyces cerevisiae. journal November 1992
A mutant mitochondrial respiratory chain assembly protein causes complex III deficiency in patients with tubulopathy, encephalopathy and liver failure journal July 2001
Coot model-building tools for molecular graphics journal November 2004
Clarifying the supercomplex: the higher-order organization of the mitochondrial electron transport chain journal October 2017
Assay of inorganic and organic phosphorus in the 0.1–5 nanomole range journal February 1975
UCSF Chimera?A visualization system for exploratory research and analysis journal January 2004
GRACILE Syndrome, a Lethal Metabolic Disorder with Iron Overload, Is Caused by a Point Mutation in BCS1L journal October 2002
Clinical and diagnostic characteristics of complex III deficiency due to mutations in the BCS1L gene: Complex III Deficiency and BCS1L Mutations journal April 2003
Identification and Characterization of Human cDNAs Specific to BCS1, PET112, SCO1, COX15, and COX11, Five Genes Involved in the Formation and Function of the Mitochondrial Respiratory Chain journal December 1998
Gctf: Real-time CTF determination and correction journal January 2016
The twin-arginine translocation (Tat) protein export pathway journal June 2012
Function and biogenesis of iron–sulphur proteins journal August 2009
Protein Structure Comparison by Alignment of Distance Matrices journal September 1993
Chaperone–usher pathways: diversity and pilus assembly mechanism journal April 2012
Impaired complex III assembly associated with BCS1L gene mutations in isolated mitochondrial encephalopathy journal April 2007
Molecular replacement with MOLREP journal December 2009
Self-assembled monolayers improve protein distribution on holey carbon cryo-EM supports journal November 2014
Mitochondrial Respiratory-Chain Diseases journal June 2003
Bcs1, a AAA protein of the mitochondria with a role in the biogenesis of the respiratory chain journal August 2012
MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy journal February 2017
Internal targeting signal of the BCS1 protein: a novel mechanism of import into mitochondria. journal February 1996
Phylogenetic analysis of AAA proteins journal April 2004
MonoRes: Automatic and Accurate Estimation of Local Resolution for Electron Microscopy Maps journal February 2018
Surface-modulated motion switch: Capture and release of iron-sulfur protein in the cytochrome bc1 complex journal August 2006

Similar Records

Folding of a large protein at high structural resolution
Journal Article · Wed Dec 11 23:00:00 EST 2013 · Proc. Natl. Acad. Sci. USA · OSTI ID:1111162

Structural Characterization of the ATPase Reaction Cycle of Endosomal AAA Protein Vps4
Journal Article · Thu Jun 18 00:00:00 EDT 2015 · Journal of Molecular Biology · OSTI ID:1186889

The structure of LepA, the ribosomal back translocase (2008).
Journal Article · Mon Jun 02 20:00:00 EDT 2008 · Proc. Natl. Acad. Sci. USA · OSTI ID:1006615

Related Subjects