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Engineering cyanobacteria as photosynthetic feedstock factories

Journal Article · · Photosynthesis Research
 [1];  [2]
  1. Harvard Medical School, Boston, MA (United States). Dept. of Systems Biology; MSU DOE Plant Research Laboratory
  2. Michigan State Univ., East Lansing, MI (United States). MSU-DOE Plant Research Laboratory; Michigan State Univ., East Lansing, MI (United States). Dept. of Biochemistry and Molecular Biology
Carbohydrate feedstocks are at the root of bioindustrial production and are needed in greater quantities than ever due to increased prioritization of renewable fuels and reduction of carbon emissions. Cyanobacteria possess a number of features that make them well-suited as an alternative feedstock crop in comparison to traditional, terrestrial plant species. Recent advances in genetic engineering, as well as promising preliminary investigations of cyanobacteria in a number of distinct production regimes have illustrated the potential of these aquatic phototrophs as biosynthetic chasses. Further improvements in strain productivities and design, along with enhanced understanding of photosynthetic metabolism in cyanobacteria may pave the way to translate cyanobacterial theoretical potential into realized application.
Research Organization:
Michigan State Univ., East Lansing, MI (United States). MSU-DOE Plant Research Laboratory
Sponsoring Organization:
USDOE Office of Science (SC), Basic Energy Sciences (BES) (SC-22)
Grant/Contract Number:
FG02-91ER20021
OSTI ID:
1603305
Journal Information:
Photosynthesis Research, Journal Name: Photosynthesis Research Journal Issue: 3 Vol. 123; ISSN 0166-8595
Publisher:
SpringerCopyright Statement
Country of Publication:
United States
Language:
English

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AraBAD Based Toolkit for Gene Expression and Metabolic Robustness Improvement in Synechococcus elongatus journal December 2017
Broad-host-range vector system for synthetic biology and biotechnology in cyanobacteria journal July 2014
Synthetic photosynthetic consortia define interactions leading to robustness and photoproduction journal January 2017
The Regulation of Light Sensing and Light-Harvesting Impacts the Use of Cyanobacteria as Biotechnology Platforms journal July 2014
The Response Regulator Slr1588 Regulates spsA But Is Not Crucial for Salt Acclimation of Synechocystis sp. PCC 6803 journal June 2017
Tiny Microbes with a Big Impact: The Role of Cyanobacteria and Their Metabolites in Shaping Our Future journal May 2016
Additional file 1 of Construction and analysis of an artificial consortium based on the fast-growing cyanobacterium Synechococcus elongatus UTEX 2973 to produce the platform chemical 3-hydroxypropionic acid from CO2 image January 2020
Additional file 2 of Construction and analysis of an artificial consortium based on the fast-growing cyanobacterium Synechococcus elongatus UTEX 2973 to produce the platform chemical 3-hydroxypropionic acid from CO2 image January 2020
Additional file 3 of Construction and analysis of an artificial consortium based on the fast-growing cyanobacterium Synechococcus elongatus UTEX 2973 to produce the platform chemical 3-hydroxypropionic acid from CO2 image January 2020
Additional file 4 of Construction and analysis of an artificial consortium based on the fast-growing cyanobacterium Synechococcus elongatus UTEX 2973 to produce the platform chemical 3-hydroxypropionic acid from CO2 image January 2020
Additional file 6 of Construction and analysis of an artificial consortium based on the fast-growing cyanobacterium Synechococcus elongatus UTEX 2973 to produce the platform chemical 3-hydroxypropionic acid from CO2 image January 2020
Additional file 7 of Construction and analysis of an artificial consortium based on the fast-growing cyanobacterium Synechococcus elongatus UTEX 2973 to produce the platform chemical 3-hydroxypropionic acid from CO2 image January 2020
Additional file 2 of Cross-feeding between cyanobacterium Synechococcus and Escherichia coli in an artificial autotrophic–heterotrophic coculture system revealed by integrated omics analysis image January 2022
Additional file 3 of Cross-feeding between cyanobacterium Synechococcus and Escherichia coli in an artificial autotrophic–heterotrophic coculture system revealed by integrated omics analysis image January 2022
Additional file 4 of Cross-feeding between cyanobacterium Synechococcus and Escherichia coli in an artificial autotrophic–heterotrophic coculture system revealed by integrated omics analysis image January 2022
Additional file 5 of Cross-feeding between cyanobacterium Synechococcus and Escherichia coli in an artificial autotrophic–heterotrophic coculture system revealed by integrated omics analysis image January 2022
Additional file 6 of Cross-feeding between cyanobacterium Synechococcus and Escherichia coli in an artificial autotrophic–heterotrophic coculture system revealed by integrated omics analysis image January 2022
Improving metabolite production in microbial co-cultures using a spatially constrained hydrogel: Improving Metabolite Production in Microbial Co-cultures journal January 2017
Applications of stable isotope-based metabolomics and fluxomics toward synthetic biology of cyanobacteria journal December 2019
The potential of Synechococcus elongatus UTEX 2973 for sugar feedstock production journal April 2016
Engineering the methylerythritol phosphate pathway in cyanobacteria for photosynthetic isoprene production from CO 2 journal January 2016
Carbon recycling by cyanobacteria: improving CO2 fixation through chemical production journal August 2017
Mimicking lichens: incorporation of yeast strains together with sucrose-secreting cyanobacteria improves survival, growth, ROS removal, and lipid production in a stable mutualistic co-culture production platform journal March 2017
Construction and analysis of an artificial consortium based on the fast-growing cyanobacterium Synechococcus elongatus UTEX 2973 to produce the platform chemical 3-hydroxypropionic acid from CO2 journal May 2020
Significance and Challenges of Biomass as a Suitable Feedstock for Bioenergy and Biochemical Production: A Review journal December 2018
Unraveling Flooding Dynamics and Nutrients’ Controls upon Phytoplankton Functional Dynamics in Amazonian Floodplain Lakes journal January 2019

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