Into the wild: new yeast genomes from natural environments and new tools for their analysis

Libkind, D.; Peris, D.; Cubillos, F. A.; Steenwyk, J. L.; Opulente, D. A.; Langdon, Q. K.; Rokas, A.; Hittinger, C. T.

doi:10.1093/femsyr/foaa008

Title: Into the wild: new yeast genomes from natural environments and new tools for their analysis

Journal Article · Mon Feb 03 00:00:00 EST 2020 · FEMS Yeast Research

DOI:https://doi.org/10.1093/femsyr/foaa008· OSTI ID:1600974

^[1]; Peris, D. ^[2]; Cubillos, F. A. ^[3];

^[4]; Opulente, D. A. ^[5]; Langdon, Q. K. ^[6];

^[4];

^[5]

National Council for Scientific and Technical Research (CONICET)-National Univ. of Comahue, Bariloche (Argentina). Patagonian Andean Inst. of Biological and Geoenvironmental Technologies (IPATEC) and Reference Center for Yeast and Brewing Technology (CRELTEC)
Spanish National Research Council (CSIC), Valencia (Spain). Inst. of Agrochemistry and Food Technology
Millennium Inst. for Integrative Biology (iBio), Santiago (Chile); Univ. of Santiago (USACH) (Chile)
Vanderbilt Univ., Nashville, TN (United States)
Univ. of Wisconsin, Madison, WI (United States). Center for Genomic Science Innovation, Lab. of Genetics, Wisconsin Energy Inst., J. F. Crow Inst. for the Study of Evolution, and DOE Great Lakes Bioenergy Research Center
Univ. of Wisconsin, Madison, WI (United States). Center for Genomic Science Innovation, Wisconsin Energy Inst. and J. F. Crow Inst. for the Study of Evolution

Genomic studies of yeasts from the wild have increased significantly in the past few years. This revolution has been fueled by advances in high-throughput sequencing technologies and a better understanding of yeast ecology and phylogeography, especially for biotechnologically important species. The present review aims to first introduce new bioinformatic tools available for the generation and analysis of yeast genomes. Furthermore, we assess the accumulated genomic data of wild isolates of industrially relevant species, such as Saccharomyces spp., which provide unique opportunities to further investigate the domestication processes associated with the fermentation industry and opportunistic pathogenesis. The availability of genome sequences of other less conventional yeasts obtained from the wild has also increased substantially, including representatives of the phyla Ascomycota (e.g. Hanseniaspora) and Basidiomycota (e.g. Phaffia). Here, we review salient examples of both fundamental and applied research that demonstrate the importance of continuing to sequence and analyze genomes of wild yeasts.

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Research Organization:: Univ. of Wisconsin, Madison, WI (United States)

Sponsoring Organization:: USDOE Office of Science (SC), Biological and Environmental Research (BER); National Science Foundation (NSF); USDA National Institute of Food and Agriculture; National Scientific and Technical Research Council

Contributing Organization:: DOE Great Lakes Bioenergy Research Center

Grant/Contract Number:: SC0018409; DEB-1442148; PIP11220130100392CO

OSTI ID:: 1600974

Journal Information:: FEMS Yeast Research, Vol. 20, Issue 2; ISSN 1567-1356

Publisher:: Oxford University PressCopyright Statement

Country of Publication:: United States

Language:: English

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Cited by: 25 works

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