Contrast enhancement of brain tumors at different MR filed strengths: Comparison of 0.5 T and 2.0 T

Journal Article · Thu Sep 01 04:00:00 EDT 1994 · AJNR. American Journal of Neuroradiology

OSTI ID:160067

Chang, Kee Hyun; Ra, Dong Gyr; Han, Moon Hee ^[1]

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1. Seoul National Univ. College of Medicine (Korea, Republic of)

Purpose: To compare the degree of MR contrast enhancement at 0.5 T and 2.0t in various brain tumors. Methods: MR images were studied prospectively in each of 31 patients with brain tumors (11 gliomas, 6 meningiomas, 6 neurinomas, and 8 others) before and after intravenous injection of gadopentetate dimeglumine. In every patient, both 0.5-T and 2.0-T MR studies were done within 1 week. Each patient received an initialstandardd dose (0.1 mmol/kg) of gadopentetate dimeglumine, followed by a subsequent 0.1-mmol/kg dose (total, double dose) in MR of each field strength. MR was done before and after each injection of the contrast agent. Degree of contrast enhancement in the lesions was assessed both visually and quantitatively. Results: With standard-dose study, the tumor enhancement was visually stronger at 2.0 T than at 0.5 T in 9 gliomas. In extraaxial tumors there was visually no or minimal difference between 0.5 T and 2.0 T. Overall mean contrast-enhancement ratio and tumor and brain contrast-to-noise ratio were higher at 2.0 T than at 0.5 T by 53% and 108%, respectively. The double-dose study showed higher contrast-enhancement ratio and contrast-to-noise ratio than the standard-dose study at both field strengths, and the differences between 0.5 T and 2.0 T were almost similar to those of the standard-dose study. The degree of contrast enhancement with the standard dose at 2.0 T was comparable to that of the double dose at 0.5 T in most intraaxial tumors. Conclusion: The results suggest that effect of contrast enhancement increases with the field strength. Therefore, reevaluation of optimal doses of contrast media may be needed in a variety of brain lesions at each field strength. 12 refs., 3 figs., 3 tabs.

• OSTI ID: 160067
• Journal Information: AJNR. American Journal of Neuroradiology, Journal Name: AJNR. American Journal of Neuroradiology Journal Issue: 8 Vol. 15; ISSN 0195-6108; ISSN AAJNDL
• Country of Publication: United States
• Language: English

Related Subjects

55 BIOLOGY AND MEDICINE
BASIC STUDIES
BRAIN
CONTRAST MEDIA
DOSE-RESPONSE RELATIONSHIPS
GLIOMAS
INTRAVENOUS INJECTION
MAGNETIC RESONANCE
NMR IMAGING