skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: The neuraminidase of A(H3N2) influenza viruses circulating since 2016 is antigenically distinct from the A/Hong Kong/4801/2014 vaccine strain

Authors:
; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; more »; ; ; ; « less
Publication Date:
Research Org.:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Org.:
USDOE Office of Science (SC)
OSTI Identifier:
1599430
Resource Type:
Journal Article
Journal Name:
Nat. Microbio.
Additional Journal Information:
Journal Volume: 4; Journal Issue: 08, 2019
Country of Publication:
United States
Language:
ENGLISH

Citation Formats

Wan, Hongquan, Gao, Jin, Yang, Hua, Yang, Shuang, Harvey, Ruth, Chen, Yao-Qing, Zheng, Nai-Ying, Chang, Jessie, Carney, Paul J., Li, Xing, Plant, Ewan, Jiang, Lianlian, Couzens, Laura, Wang, Carol, Strohmeier, Shirin, Wu, Wells W., Shen, Rong-Fong, Krammer, Florian, Cipollo, John F., Wilson, Patrick C., Stevens, James, Wan, Xiu-Feng, Eichelberger, Maryna C., and Ye, Zhiping. The neuraminidase of A(H3N2) influenza viruses circulating since 2016 is antigenically distinct from the A/Hong Kong/4801/2014 vaccine strain. United States: N. p., 2020. Web. doi:10.1038/s41564-019-0522-6.
Wan, Hongquan, Gao, Jin, Yang, Hua, Yang, Shuang, Harvey, Ruth, Chen, Yao-Qing, Zheng, Nai-Ying, Chang, Jessie, Carney, Paul J., Li, Xing, Plant, Ewan, Jiang, Lianlian, Couzens, Laura, Wang, Carol, Strohmeier, Shirin, Wu, Wells W., Shen, Rong-Fong, Krammer, Florian, Cipollo, John F., Wilson, Patrick C., Stevens, James, Wan, Xiu-Feng, Eichelberger, Maryna C., & Ye, Zhiping. The neuraminidase of A(H3N2) influenza viruses circulating since 2016 is antigenically distinct from the A/Hong Kong/4801/2014 vaccine strain. United States. doi:10.1038/s41564-019-0522-6.
Wan, Hongquan, Gao, Jin, Yang, Hua, Yang, Shuang, Harvey, Ruth, Chen, Yao-Qing, Zheng, Nai-Ying, Chang, Jessie, Carney, Paul J., Li, Xing, Plant, Ewan, Jiang, Lianlian, Couzens, Laura, Wang, Carol, Strohmeier, Shirin, Wu, Wells W., Shen, Rong-Fong, Krammer, Florian, Cipollo, John F., Wilson, Patrick C., Stevens, James, Wan, Xiu-Feng, Eichelberger, Maryna C., and Ye, Zhiping. Mon . "The neuraminidase of A(H3N2) influenza viruses circulating since 2016 is antigenically distinct from the A/Hong Kong/4801/2014 vaccine strain". United States. doi:10.1038/s41564-019-0522-6.
@article{osti_1599430,
title = {The neuraminidase of A(H3N2) influenza viruses circulating since 2016 is antigenically distinct from the A/Hong Kong/4801/2014 vaccine strain},
author = {Wan, Hongquan and Gao, Jin and Yang, Hua and Yang, Shuang and Harvey, Ruth and Chen, Yao-Qing and Zheng, Nai-Ying and Chang, Jessie and Carney, Paul J. and Li, Xing and Plant, Ewan and Jiang, Lianlian and Couzens, Laura and Wang, Carol and Strohmeier, Shirin and Wu, Wells W. and Shen, Rong-Fong and Krammer, Florian and Cipollo, John F. and Wilson, Patrick C. and Stevens, James and Wan, Xiu-Feng and Eichelberger, Maryna C. and Ye, Zhiping},
abstractNote = {},
doi = {10.1038/s41564-019-0522-6},
journal = {Nat. Microbio.},
number = 08, 2019,
volume = 4,
place = {United States},
year = {2020},
month = {2}
}

Works referenced in this record:

Identification of Hemagglutinin Residues Responsible for H3N2 Antigenic Drift during the 2014–2015 Influenza Season
journal, July 2015


Contemporary H3N2 influenza viruses have a glycosylation site that alters binding of antibodies elicited by egg-adapted vaccine strains
journal, November 2017

  • Zost, Seth J.; Parkhouse, Kaela; Gumina, Megan E.
  • Proceedings of the National Academy of Sciences, Vol. 114, Issue 47
  • DOI: 10.1073/pnas.1712377114

A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine
journal, October 2017


Antibody to Influenza Virus Neuraminidase: An Independent Correlate of Protection
journal, April 2015

  • Monto, Arnold S.; Petrie, Joshua G.; Cross, Rachel T.
  • Journal of Infectious Diseases, Vol. 212, Issue 8
  • DOI: 10.1093/infdis/jiv195

An Epidemiologically Significant Epitope of a 1998 Human Influenza Virus Neuraminidase Forms a Highly Hydrated Interface in the NA–Antibody Complex
journal, February 2006

  • Venkatramani, Lalitha; Bochkareva, Elena; Lee, Janis T.
  • Journal of Molecular Biology, Vol. 356, Issue 3
  • DOI: 10.1016/j.jmb.2005.11.061

Influenza Infection in Humans Induces Broadly Cross-Reactive and Protective Neuraminidase-Reactive Antibodies
journal, April 2018


Three-dimensional structure of a complex of antibody with influenza virus neuraminidase
journal, March 1987

  • Colman, P. M.; Laver, W. G.; Varghese, J. N.
  • Nature, Vol. 326, Issue 6111
  • DOI: 10.1038/326358a0

Inference of Macromolecular Assemblies from Crystalline State
journal, September 2007


Interim Estimates of 2016–17 Seasonal Influenza Vaccine Effectiveness — United States, February 2017
journal, February 2017

  • Flannery, Brendan; Chung, Jessie R.; Thaker, Swathi N.
  • MMWR. Morbidity and Mortality Weekly Report, Vol. 66, Issue 6
  • DOI: 10.15585/mmwr.mm6606a3

Generation of influenza A viruses entirely from cloned cDNAs
journal, August 1999

  • Neumann, G.; Watanabe, T.; Ito, H.
  • Proceedings of the National Academy of Sciences, Vol. 96, Issue 16
  • DOI: 10.1073/pnas.96.16.9345

Prediction of post-translational glycosylation and phosphorylation of proteins from the amino acid sequence
journal, June 2004

  • Blom, Nikolaj; Sicheritz-Pontén, Thomas; Gupta, Ramneek
  • PROTEOMICS, Vol. 4, Issue 6
  • DOI: 10.1002/pmic.200300771

Likelihood-enhanced fast translation functions
journal, March 2005

  • McCoy, Airlie J.; Grosse-Kunstleve, Ralf W.; Storoni, Laurent C.
  • Acta Crystallographica Section D Biological Crystallography, Vol. 61, Issue 4
  • DOI: 10.1107/S0907444905001617

Coot model-building tools for molecular graphics
journal, November 2004

  • Emsley, Paul; Cowtan, Kevin
  • Acta Crystallographica Section D Biological Crystallography, Vol. 60, Issue 12, p. 2126-2132
  • DOI: 10.1107/S0907444904019158

Use of TLS parameters to model anisotropic displacements in macromolecular refinement
journal, January 2001

  • Winn, M. D.; Isupov, M. N.; Murshudov, G. N.
  • Acta Crystallographica Section D Biological Crystallography, Vol. 57, Issue 1
  • DOI: 10.1107/S0907444900014736

MolProbity: all-atom contacts and structure validation for proteins and nucleic acids
journal, May 2007

  • Davis, I. W.; Leaver-Fay, A.; Chen, V. B.
  • Nucleic Acids Research, Vol. 35, Issue Web Server
  • DOI: 10.1093/nar/gkm216

IMGT/V-QUEST: the highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis
journal, May 2008

  • Brochet, X.; Lefranc, M. -P.; Giudicelli, V.
  • Nucleic Acids Research, Vol. 36, Issue Web Server
  • DOI: 10.1093/nar/gkn316