skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Four amino acids define the CO[subscript 2] binding pocket of enoyl-CoA carboxylases/reductases

Journal Article · · Proc. Natl. Acad. Sci. USA

Research Organization:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Organization:
FOREIGN
OSTI ID:
1542997
Journal Information:
Proc. Natl. Acad. Sci. USA, Vol. 116, Issue (28) ; 07, 2019
Country of Publication:
United States
Language:
ENGLISH

References (37)

Roles of the Redox-Active Disulfide and Histidine Residues Forming a Catalytic Dyad in Reactions Catalyzed by 2-Ketopropyl Coenzyme M Oxidoreductase/Carboxylase journal July 2011
A feeling for the numbers in biology journal December 2009
A Chemo-Enzymatic Road Map to the Synthesis of CoA Esters journal April 2016
Theoretical Analysis of the Reaction Mechanism of Biotin Carboxylase journal January 2008
Phosphoglycolate production catalyzed by ribulose diphosphate carboxylase journal November 1971
CO 2 and O 2 Distribution in Rubisco Suggests the Small Subunit Functions as a CO 2 Reservoir journal February 2014
The use of ene adducts to study and engineer enoyl-thioester reductases journal April 2015
Modelling the reaction mechanism of ribulose-1,5-bisphosphate carboxylase/oxygenase and consequences for kinetic parameters: Rubisco kinetics journal February 2013
Despite slow catalysis and confused substrate specificity, all ribulose bisphosphate carboxylases may be nearly perfectly optimized journal April 2006
Evolutionary history and biotechnological future of carboxylases journal November 2013
Carboxylation mechanism and stereochemistry of crotonyl-CoA carboxylase/reductase, a carboxylating enoyl-thioester reductase journal May 2009
Synthesis of C5-dicarboxylic acids from C2-units involving crotonyl-CoA carboxylase/reductase: The ethylmalonyl-CoA pathway journal June 2007
Substitution of a conserved catalytic dyad into 2-KPCC causes loss of carboxylation activity journal August 2016
Direct evidence for a covalent ene adduct intermediate in NAD(P)H-dependent enzymes journal November 2013
Structural mechanism of RuBisCO activation by carbamylation of the active site lysine journal October 2012
Unusual carbon fixation gives rise to diverse polyketide extender units journal December 2011
Utilisation of CO2 as a chemical feedstock: opportunities and challenges journal January 2007
A synthetic pathway for the fixation of carbon dioxide in vitro journal November 2016
Substrate isomerization inhibits ribulosebisphospate carboxylase-oxygenase during catalysis journal January 1990
The most abundant protein in the world journal November 1979
Characterization of covalent Ene adduct intermediates in “hydride equivalent” transfers in a dihydropyridine model for NADH reduction reactions journal February 2012
CO 2 utilization: Developments in conversion processes journal March 2017
InhA, the enoyl-thioester reductase from Mycobacterium tuberculosis forms a covalent adduct during catalysis journal September 2018
Screening and Engineering the Synthetic Potential of Carboxylating Reductases from Central Metabolism and Polyketide Biosynthesis journal September 2015
Design and analysis of synthetic carbon fixation pathways journal April 2010
A short history of RubisCO: the rise and fall (?) of Nature's predominant CO2 fixing enzyme journal February 2018
Rational Control of Polyketide Extender Units by Structure-Based Engineering of a Crotonyl-CoA Carboxylase/Reductase in Antimycin Biosynthesis journal September 2015
Carboxylases in Natural and Synthetic Microbial Pathways journal October 2011
Frontiers, Opportunities, and Challenges in Biochemical and Chemical Catalysis of CO 2 Fixation journal June 2013
Structural basis for carbon dioxide binding by 2-ketopropyl coenzyme M oxidoreductase/carboxylase journal December 2010
Carboxylases in Natural and Synthetic Microbial Pathways journal October 2011
Substrate isomerization inhibits ribulosebisphospate carboxylase-oxygenase during catalysis journal January 1990
Phosphoglycolate production catalyzed by ribulose diphosphate carboxylase journal November 1971
Roles of the Redox-Active Disulfide and Histidine Residues Forming a Catalytic Dyad in Reactions Catalyzed by 2-Ketopropyl Coenzyme M Oxidoreductase/Carboxylase journal July 2011
InhA, the enoyl-thioester reductase from Mycobacterium tuberculosis forms a covalent adduct during catalysis journal September 2018
Rational Control of Polyketide Extender Units by Structure‐Based Engineering of a Crotonyl‐CoA Carboxylase/Reductase in Antimycin Biosynthesis journal September 2015
A Chemo-Enzymatic Road Map to the Synthesis of CoA Esters text January 2016

Similar Records

Four amino acids define the CO 2 binding pocket of enoyl-CoA carboxylases/reductases
Journal Article · Wed Jun 26 00:00:00 EDT 2019 · Proceedings of the National Academy of Sciences of the United States of America · OSTI ID:1542997

Combining Promiscuous Acyl-CoA Oxidase and Enoyl-CoA Carboxylase/Reductases for Atypical Polyketide Extender Unit Biosynthesis
Journal Article · Sun Jul 01 00:00:00 EDT 2018 · Cell Chemical Biology · OSTI ID:1542997

A crotonyl-CoA reductase-carboxylase independent pathway for assembly of unusual alkylmalonyl-CoA polyketide synthase extender units
Journal Article · Thu Dec 01 00:00:00 EST 2016 · Nature Communications · OSTI ID:1542997

Related Subjects