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Title: Fate Decision Between Group 3 Innate Lymphoid and Conventional NK Cell Lineages by Notch Signaling in Human Circulating Hematopoietic Progenitors

Journal Article · · Journal of Immunology
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Not provided.

Research Organization:
National Academy of Sciences, Washington, DC (United States)
Sponsoring Organization:
USDOE Office of Environment, Health, Safety and Security (AU)
DOE Contract Number:
HS0000031
OSTI ID:
1542040
Journal Information:
Journal of Immunology, Vol. 199, Issue 8; ISSN 0022-1767
Publisher:
The American Association of Immunologists, Inc.
Country of Publication:
United States
Language:
English

References (52)

Innate Lymphoid Cells in Inflammation and Immunity journal September 2014
Innate lymphoid cells — a proposal for uniform nomenclature journal January 2013
Development, Differentiation, and Diversity of Innate Lymphoid Cells journal September 2014
Transcriptional programs define molecular characteristics of innate lymphoid cell classes and subsets journal January 2015
Group 3 innate lymphoid cells (ILC3s): Origin, differentiation, and plasticity in humans and mice: Highlights - (Mini-Review) journal June 2015
Human innate lymphoid cells journal July 2014
Natural Aryl Hydrocarbon Receptor Ligands Control Organogenesis of Intestinal Lymphoid Follicles journal October 2011
A T-bet gradient controls the fate and function of CCR6−RORγt+ innate lymphoid cells journal January 2013
AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch journal November 2011
Lineage relationships of human interleukin-22–producing CD56+ RORγt+ innate lymphoid cells and conventional natural killer cells journal March 2013
Human RORγt+CD34+ Cells Are Lineage-Specified Progenitors of Group 3 RORγt+ Innate Lymphoid Cells journal December 2014
Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells journal December 2009
IL-7 and IL-15 independently program the differentiation of intestinal CD3 − NKp46 + cell subsets from Id2-dependent precursors journal February 2010
Notch, Id2, and RORγt sequentially orchestrate the fetal development of lymphoid tissue inducer cells journal March 2012
Differentiation of Type 1 ILCs from a Common Progenitor to All Helper-like Innate Lymphoid Cell Lineages journal April 2014
A committed precursor to innate lymphoid cells journal February 2014
AHR and the Transcriptional Regulation of Type-17/22 ILC journal January 2012
Transcription factor RORα is critical for nuocyte development journal January 2012
T Cell Factor 1 Is Required for Group 2 Innate Lymphoid Cell Generation journal April 2013
Notch signaling is necessary for adult, but not fetal, development of RORγt+ innate lymphoid cells journal September 2011
The transcription factor T-bet is essential for the development of NKp46+ innate lymphocytes via the Notch pathway journal March 2013
Notch signaling in group 3 innate lymphoid cells modulates their plasticity journal May 2016
Transforming growth factor–β and Notch ligands act as opposing environmental cues in regulating the plasticity of type 3 innate lymphoid cells journal May 2016
Notch Activation Induces the Generation of Functional NK Cells from Human Cord Blood CD34-Positive Cells Devoid of IL-15 journal May 2009
Notch Increases T/NK Potential of Human Hematopoietic Progenitors and Inhibits B Cell Differentiation at a Pro-B Stage journal July 2009
Age-Associated Changes in the Differentiation Potentials of Human Circulating Hematopoietic Progenitors to T- or NK-Lineage Cells journal May 2013
Notch Signaling at Later Stages of NK Cell Development Enhances KIR Expression and Functional Maturation journal August 2014
Modulation of Signal Strength Switches Notch from an Inducer of T Cells to an Inducer of ILC2 journal January 2013
Tissue residency of innate lymphoid cells in lymphoid and nonlymphoid organs journal October 2015
Linkage between Dendritic and T Cell Commitments in Human Circulating Hematopoietic Progenitors journal May 2014
High-throughput flow cytometry: Validation in microvolume bioassays journal May 2003
Hierarchy of Notch–Delta interactions promoting T cell lineage commitment and maturation journal January 2007
Therapeutic antibody targeting of individual Notch receptors journal April 2010
Induction of T Cell Development from Hematopoietic Progenitor Cells by Delta-like-1 In Vitro journal December 2002
ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays journal August 2009
Identification of a Human Natural Killer Cell Lineage-Restricted Progenitor in Fetal and Adult Tissues journal August 2015
Revised map of the human progenitor hierarchy shows the origin of macrophages and dendritic cells in early lymphoid development journal June 2010
Molecular characterization of early human T/NK and B-lymphoid progenitor cells in umbilical cord blood journal December 2004
Human intrathymic lineage commitment is marked by differential CD7 expression: identification of CD7− lympho-myeloid thymic progenitors journal February 2008
Notch ligands potentiate IL-7-driven proliferation and survival of human thymocyte precursors journal April 2009
CSL–MAML-dependent Notch1 signaling controls T lineage–specific IL-7Rα gene expression in early human thymopoiesis and leukemia journal April 2009
Interleukin-7 receptor expression: intelligent design journal February 2007
Transcriptional Control of Early T and B Cell Developmental Choices journal March 2014
Activated Notch Supports Development of Cytokine Producing NK Cells Which Are Hyporesponsive and Fail to Acquire NK Cell Effector Functions journal February 2009
Evidence for discrete stages of human natural killer cell differentiation in vivo journal April 2006
Lymphoid priming in human bone marrow begins before expression of CD10 with upregulation of L-selectin journal September 2012
Deficient T Cell Fate Specification in Mice with an Induced Inactivation of Notch1 journal May 1999
Cutting Edge: Thymic NK Cells Develop Independently from T Cell Precursors journal October 2010
Identification of an NK/T cell–restricted progenitor in adult bone marrow contributing to bone marrow– and thymic-dependent NK cells journal July 2010
Adult T-cell progenitors retain myeloid potential journal April 2008
Early T-cell progenitors are the major granulocyte precursors in the adult mouse thymus journal January 2013
In vitro assays misrepresent in vivo lineage potentials of murine lymphoid progenitors journal March 2011

Cited By (7)

KLRG1 and NKp46 discriminate subpopulations of human CD117+CRTH2− ILCs biased toward ILC2 or ILC3 journal June 2019
Notch Signaling as a Regulator of the Tumor Immune Response: To Target or Not To Target? journal July 2018
Antiproliferative and Immunoregulatory Effects of Azelaic Acid Against Acute Myeloid Leukemia via the Activation of Notch Signaling Pathway journal November 2019
Multifactorial Contribution of Notch Signaling in Head and Neck Squamous Cell Carcinoma journal March 2019
Multifactorial Contribution of Notch Signaling in Head and Neck Squamous Cell Carcinoma text January 2019
Interleukin-7 Receptor Alpha in Innate Lymphoid Cells: More Than a Marker journal December 2019
Identification of Novel Human NK Cell Progenitor Subsets journal December 2017

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