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Melanotropin analogs for potential radiopharmaceuticals for diagnosis and treatment of melanoma

Patent ·
OSTI ID:1531467
A compound for use as a diagnostic or therapeutic pharmaceutical and method of using the same where the compound consists essentially of an alpha-melanotropin stimulating hormone analog which has integrally located a radionuclide. The radionuclide is administered to the body in an amount sufficient to allow uptake and retention by the tumor cells.
Research Organization:
Univ. of Missouri, Columbia, MO (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
FG02-93ER61661
Assignee:
The Curators of the University of Missouri (Columbia, MO)
Patent Number(s):
6,680,045
Application Number:
09/841,407
OSTI ID:
1531467
Country of Publication:
United States
Language:
English

References (3)

Cyclic Melanotropins. 9. 7-D-Phenylalanine Analogues of the Active-Site Sequence journal May 1985
Synthesis and Characterization of Rhenium-Complexed α-Melanotropin Analogs journal May 1997
Radiolabeled peptides and other ligands for receptors overexpressed in tumor cells for imaging neoplasms journal August 1996

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