Human-Murine Transthyretin Heterotetramers Are Kinetically Stable and Non-amyloidogenic
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journal
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January 2008 |
Deletion of murine tau gene increases tau aggregation in a human mutant tau transgenic mouse model
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journal
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July 2010 |
Converging concepts of protein folding in vitro and in vivo
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journal
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June 2009 |
Genetic dissection of myocilin glaucoma
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journal
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January 2004 |
Myocilin and glaucoma: facts and ideas
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journal
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July 2002 |
Targeting the ER-autophagy system in the trabecular meshwork to treat glaucoma
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journal
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March 2016 |
Clinical Features Associated with Mutations in the Chromosome 1 Open-Angle Glaucoma Gene ( GLC1A )
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journal
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April 1998 |
Myocilin Glaucoma
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journal
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November 2002 |
Prevalence of Mutations in TIGR/Myocilin in Patients with Adult and Juvenile Primary Open-Angle Glaucoma
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journal
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November 1998 |
Expression of Mutated Mouse Myocilin Induces Open-Angle Glaucoma in Transgenic Mice
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journal
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November 2006 |
Transgenic Mice Expressing the Tyr437His Mutant of Human Myocilin Protein Develop Glaucoma
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journal
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May 2008 |
Mutant Myocilin Nonsecretion In Vivo Is Not Sufficient To Cause Glaucoma
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journal
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November 2006 |
Reduction of ER stress via a chemical chaperone prevents disease phenotypes in a mouse model of primary open angle glaucoma
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journal
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September 2011 |
The Glaucoma-Associated Olfactomedin Domain of Myocilin Forms Polymorphic Fibrils That Are Constrained by Partial Unfolding and Peptide Sequence
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journal
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February 2014 |
Rescue of Glaucoma-Causing Mutant Myocilin Thermal Stability by Chemical Chaperones
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journal
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March 2010 |
Expression and Purification of Soluble His6-Tagged TEV Protease
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book
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January 2009 |
Protein Identification and Analysis Tools on the ExPASy Server
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book
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January 2005 |
HKL -3000: the integration of data reduction and structure solution – from diffraction images to an initial model in minutes
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journal
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July 2006 |
Phaser crystallographic software
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journal
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July 2007 |
Features and development of Coot
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journal
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March 2010 |
Improvements to the APBS biomolecular solvation software suite: Improvements to the APBS Software Suite
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journal
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October 2017 |
Studies in Molecular Dynamics. I. General Method
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journal
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August 1959 |
?-Helix formation: Discontinuous molecular dynamics on an intermediate-resolution protein model
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journal
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January 2001 |
Simulations and Experiments Delineate Amyloid Fibrilization by Peptides Derived from Glaucoma-Associated Myocilin
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journal
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May 2018 |
Extending the PRIME model for protein aggregation to all 20 amino acids
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journal
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September 2010 |
Molecular dynamics simulations of spontaneous fibril formation by random-coil peptides
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journal
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November 2004 |
Molecular dynamics simulations at constant pressure and/or temperature
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journal
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February 1980 |
Structural basis for misfolding in myocilin-associated glaucoma
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journal
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December 2014 |
The Stability of Myocilin Olfactomedin Domain Variants Provides New Insight into Glaucoma as a Protein Misfolding Disorder
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journal
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July 2011 |
Myocilin allele-specific glaucoma phenotype database
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journal
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February 2008 |
Founder TIGR/myocilin mutations for glaucoma in the Quebec population
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journal
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September 2002 |
Molecular Details of Olfactomedin Domains Provide Pathway to Structure-Function Studies
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journal
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June 2015 |
The Glaucoma-associated Olfactomedin Domain of Myocilin Is a Novel Calcium Binding Protein
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journal
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November 2012 |
Alzheimer's Disease: Genes, Proteins, and Therapy
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journal
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April 2001 |
Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation.
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journal
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July 1990 |
Species-dependent structural polymorphism of Y145Stop prion protein amyloid revealed by solid-state NMR spectroscopy
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journal
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September 2017 |
Familial Alzheimer’s Disease Mutations within the Amyloid Precursor Protein Alter the Aggregation and Conformation of the Amyloid-β Peptide
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journal
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February 2017 |
Atomic-Resolution Three-Dimensional Structure of Amyloid β Fibrils Bearing the Osaka Mutation
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journal
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November 2014 |
Aggregation-triggering segments of SOD1 fibril formation support a common pathway for familial and sporadic ALS
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journal
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December 2013 |
Common fibrillar spines of amyloid-β and human islet amyloid polypeptide revealed by microelectron diffraction and structure-based inhibitors
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journal
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December 2017 |
Amyloid Fibril Formation by the Glaucoma-Associated Olfactomedin Domain of Myocilin
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journal
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August 2012 |
Accumulation of mutant myocilins in ER leads to ER stress and potential cytotoxicity in human trabecular meshwork cells
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journal
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December 2003 |
Expression of Myocilin Mutants Sensitizes Cells to Oxidative Stress-Induced Apoptosis
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journal
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June 2010 |
Aggregated Myocilin Induces Russell Bodies and Causes Apoptosis
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journal
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January 2007 |
Reversal of mutant myocilin non-secretion and cell killing: implications for glaucoma
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journal
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April 2004 |
Glaucoma-causing myocilin mutants require the Peroxisomal targeting signal-1 receptor (PTS1R) to elevate intraocular pressure
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journal
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March 2007 |
Rodent models of glaucoma
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journal
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February 2010 |
Mutant human myocilin induces strain specific differences in ocular hypertension and optic nerve damage in mice
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journal
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July 2012 |
Mutated Mouse and Human Myocilins Have Similar Properties and Do Not Block General Secretory Pathway
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journal
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January 2006 |
Temperature sensitive secretion of mutant myocilins
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journal
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June 2006 |
Functional analysis of the glaucoma-causing TIGR/myocilin protein: Integrity of amino-terminal coiled-coil regions and olfactomedin homology domain is essential for extracellular adhesion and secretion
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journal
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June 2006 |
Histochemical Analysis of Glaucoma Caused by a Myocilin Mutation in a Human Donor Eye
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journal
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September 2018 |
ThT 101: a primer on the use of thioflavin T to investigate amyloid formation
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journal
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January 2017 |
Studies of the aggregation of mutant proteins in vitro provide insights into the genetics of amyloid diseases
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journal
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October 2002 |
Spatial Extent of Charge Repulsion Regulates Assembly Pathways for Lysozyme Amyloid Fibrils
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journal
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April 2011 |
Amyloid β-Protein Fibrillogenesis: STRUCTURE AND BIOLOGICAL ACTIVITY OF PROTOFIBRILLAR INTERMEDIATES
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journal
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September 1999 |
Structure and Misfolding of the Flexible Tripartite Coiled-Coil Domain of Glaucoma-Associated Myocilin
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journal
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November 2017 |