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Large scale production of the copper enzyme peptidylglycine monooxygenase using an automated bioreactor
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journal
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January 2007 |
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HHM Motif at the CuH-Site of Peptidylglycine Monooxygenase is a pH-Dependent Conformational Switch
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journal
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April 2013 |
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Evidence That Dioxygen and Substrate Activation Are Tightly Coupled in Dopamine β-Monooxygenase: IMPLICATIONS FOR THE REACTIVE OXYGEN SPECIES
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journal
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September 2003 |
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Peptidylglycine α-amidating monooxygenase: A multifunctional protein with catalytic, processing, and routing domains
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journal
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April 1993 |
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The Catalytic Role of the Copper Ligand H172 of Peptidylglycine α-Hydroxylating Monooxygenase (PHM): A Spectroscopic Study of the H172A Mutant †
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journal
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November 2002 |
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Features and development of Coot
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journal
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March 2010 |
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Plausible molecular mechanism for activation by fumarate and electron transfer of the dopamine β-mono-oxygenase reaction
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journal
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October 2002 |
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The Copper-Enzyme Family of Dopamine β-Monooxygenase and Peptidylglycine α-Hydroxylating Monooxygenase: Resolving the Chemical Pathway for Substrate Hydroxylation
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journal
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November 2005 |
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Stopped-Flow Studies of the Reduction of the Copper Centers Suggest a Bifurcated Electron Transfer Pathway in Peptidylglycine Monooxygenase
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journal
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March 2016 |
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Coordination of peroxide to the CuM center of peptidylglycine α-hydroxylating monooxygenase (PHM): structural and computational study
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journal
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December 2012 |
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Metal Ions in Proteins: Structural and Functional Roles
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journal
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January 1987 |
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Differential Reactivity between Two Copper Sites in Peptidylglycine α-Hydroxylating Monooxygenase
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journal
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November 2010 |
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The copper centers of tyramine β-monooxygenase and its catalytic-site methionine variants: an X-ray absorption study
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journal
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June 2010 |
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Kinetic Mechanism and Intrinsic Isotope Effects for the Peptidylglycine α-Amidating Enzyme Reaction †
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journal
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June 1998 |
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The crystal structure of human dopamine β-hydroxylase at 2.9 Å resolution
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journal
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April 2016 |
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The Hydrogen Peroxide Reactivity of Peptidylglycine Monooxygenase Supports a Cu(II)-Superoxo Catalytic Intermediate
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journal
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January 2006 |
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MolProbity : all-atom structure validation for macromolecular crystallography
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journal
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December 2009 |
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A graphical user interface to the CCP 4 program suite
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journal
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June 2003 |
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Ongoing developments in CCP 4 for high-throughput structure determination
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journal
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October 2002 |
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O2 activation by binuclear Cu sites: Noncoupled versus exchange coupled reaction mechanisms
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journal
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August 2004 |
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Dioxygen Binds End-On to Mononuclear Copper in a Precatalytic Enzyme Complex
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journal
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May 2004 |
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Probing the Peptidylglycine α-Hydroxylating Monooxygenase Active Site with Novel 4-Phenyl-3-butenoic Acid Based Inhibitors
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journal
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August 2010 |
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Hydroxylase Activity of Met471Cys Tyramine β-Monooxygenase
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journal
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September 2008 |
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Structural Investigations on the Coordination Environment of the Active-Site Copper Centers of Recombinant Bifunctional Peptidylglycine α-Amidating Enzyme †
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journal
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January 1996 |
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Amidation of Bioactive Peptides: The Structure of Peptidylglycine -Hydroxylating Monooxygenase
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journal
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November 1997 |
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X-ray Absorption Edge Spectroscopy and Computational Studies on LCuO 2 Species: Superoxide−Cu II versus Peroxide−Cu III Bonding
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journal
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June 2006 |
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Supplying Copper to the Cuproenzyme Peptidylglycine α-Amidating Monooxygenase
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journal
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January 2003 |
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A Copper–Methionine Interaction Controls the pH-Dependent Activation of Peptidylglycine Monooxygenase
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journal
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December 2011 |
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Peptide amidation
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journal
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January 1991 |
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Identification in pituitary tissue of a peptide alpha-amidation activity that acts on glycine-extended peptides and requires molecular oxygen, copper, and ascorbic acid.
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journal
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August 1983 |
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New insights into copper monooxygenases and peptide amidation: structure, mechanism and function
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journal
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August 2000 |
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The Catalytic Core of Peptidylglycine .alpha.-Hydroxylating Monooxygenase: Investigation by Site-Directed Mutagenesis, Cu X-ray Absorption Spectroscopy, and Electron Paramagnetic Resonance
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journal
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March 1995 |
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Hydrogen Tunneling in Peptidylglycine α-Hydroxylating Monooxygenase
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journal
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July 2002 |
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Substituted hippurates and hippurate analogs as substrates and inhibitors of peptidylglycine α-hydroxylating monooxygenase (PHM)
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journal
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December 2008 |
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pH-regulated metal–ligand switching in the HM loop of ATP7A: a new paradigm for metal transfer chemistry
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journal
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January 2016 |
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Major changes in copper coordination accompany reduction of peptidylglycine monooxygenase: implications for electron transfer and the catalytic mechanism
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journal
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June 2000 |
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Bifunctional Peptidylglycine α-Amidating Enzyme Requires 2 Copper Atoms for Maximum Activity
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journal
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May 1994 |
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Transition metal binding selectivity in proteins and its correlation with the phylogenomic classification of the cation diffusion facilitator protein family
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journal
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November 2017 |
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C-Terminal amidated peptides: Production by the in vitro enzymatic amidation of glycine-extended peptides and the importance of the amide to bioactivity
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journal
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June 1994 |
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Does Superoxide Channel between the Copper Centers in Peptidylglycine Monooxygenase? A New Mechanism Based on Carbon Monoxide Reactivity †
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journal
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November 1999 |
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Substrate-Induced Carbon Monoxide Reactivity Suggests Multiple Enzyme Conformations at the Catalytic Copper M-Center of Peptidylglycine Monooxygenase
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journal
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November 2016 |
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Peptide amidation: Evidence for multiple molecular forms of the amidating enzyme
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journal
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August 1988 |
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The Catalytic Mechanism of Peptidylglycine α-Hydroxylating Monooxygenase Investigated by Computer Simulation
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journal
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October 2006 |
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A "Neural" Enzyme in Nonbilaterian Animals and Algae: Preneural Origins for Peptidylglycine -Amidating Monooxygenase
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journal
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April 2012 |
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The Catalytic Copper of Peptidylglycine α-Hydroxylating Monooxygenase also Plays a Critical Structural Role
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journal
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November 2005 |
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Identification of the Five Essential Histidine Residues for Peptidylglycine Monooxygenase
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journal
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January 1996 |
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Early eukaryotic origins for cilia-associated bioactive peptide-amidating activity
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journal
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January 2016 |
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Further Characterization of Peptidylglycine α-Amidating Monooxygenase from Bovine Neurointermediate Pituitary*
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journal
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April 1987 |
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Interdomain Long-Range Electron Transfer Becomes Rate-Limiting in the Y216A Variant of Tyramine β-Monooxygenase
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journal
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February 2013 |
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Oxygen Activation by the Noncoupled Binuclear Copper Site in Peptidylglycine α-Hydroxylating Monooxygenase. Reaction Mechanism and Role of the Noncoupled Nature of the Active Site
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journal
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April 2004 |
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Isocyanide binding to the copper(I) centers of the catalytic core of peptidylglycine monooxygenase (PHMcc)
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journal
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May 2001 |
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The Catalytic Role of the Copper Ligand H172 of Peptidylglycine α-Hydroxylating Monooxygenase: A Kinetic Study of the H172A Mutant †
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journal
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December 2006 |
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Peptidylglycine-α-Hydroxylating Monooxygenase Generates Two Hydroxylated Products from Its Mechanism-Based Suicide Substrate, 4-Phenyl-3-butenoic Acid †
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journal
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July 2000 |
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Alternative mRNA splicing generates multiple forms of peptidyl-glycine alpha-amidating monooxygenase in rat atrium.
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journal
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January 1989 |
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Crystallization of soluble proteins in vapor diffusion for x-ray crystallography
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journal
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June 2007 |
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Oxygen Activation by the Noncoupled Binuclear Copper Site in Peptidylglycine α-Hydroxylating Monooxygenase. Spectroscopic Definition of the Resting Sites and the Putative Cu II M −OOH Intermediate †
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journal
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May 2004 |
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Lumenal Loop M672-P707 of the Menkes Protein (ATP7A) Transfers Copper to Peptidylglycine Monooxygenase
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journal
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June 2012 |
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Peptidylglycine α-Hydroxylating Monooxygenase: Active Site Residues, Disulfide Linkages, and a Two-Domain Model of the Catalytic Core †
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journal
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September 1997 |