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Photothermal Properties of Shape Memory Polymer Micro-Actuators for Treating Stroke

Conference ·
DOI:https://doi.org/10.1002/lsm.10007· OSTI ID:15013159

Objective--In this paper the photothermal design aspects of novel shape memory polymer (SMP) microactuators for treating stroke are presented. Materials and Methods--A total of three devices will be presented: two interventional ischemic stroke devices (coil and umbrella) and one device for releasing embolic coils (microgripper). The optical properties of SMP, methods for coupling laser light into SMP, heating distributions in the SMP devices and the impact of operating the thermally activated material in a blood vessel are presented. Results--Actuating the devices requires device temperatures in the range of 65 C-85 C. Attaining these temperatures under flow conditions requires critical engineering of the SMP optical properties, optical coupling into the SMP, and device geometries. Conclusion--Laser-activated SMP devices are a unique combination of laser-tissue and biomaterial technologies. Successful deployment of the microactuator requires well-engineered coupling of the light from the diffusing fiber through the blood into the SMP.

Research Organization:
Lawrence Livermore National Laboratory (LLNL), Livermore, CA
Sponsoring Organization:
USDOE
DOE Contract Number:
W-7405-ENG-48
OSTI ID:
15013159
Report Number(s):
UCRL-JC-142893
Country of Publication:
United States
Language:
English

References (11)

Comparison of the AngioJet Rheolytic Catheter to Surgical Thrombectomy for the Treatment of Thrombosed Hemodialysis Grafts journal October 1999
Tissue Plasminogen Activator for Acute Ischemic Stroke journal December 1995
Recovery as a measure of oriented crystalline structure in poly(ether ester)s based on poly(ethylene oxide) and poly(ethylene terephthalate) used as shape memory polymers journal January 1999
Prevention of a First Stroke: A Review of Guidelines and a Multidisciplinary Consensus Statement From the National Stroke Association journal March 1999
Unruptured Intracranial Aneurysms — Risk of Rupture and Risks of Surgical Intervention journal January 1998
Recommendations for the Management of Patients With Unruptured Intracranial Aneurysms: A Statement for Healthcare Professionals From the Stroke Council of the American Heart Association journal November 2000
Structure and properties of shape-memory polyurethane block copolymers journal May 1996
Quantitative measurements of linear birefringence during heating of native collagen journal January 1997
Thermal characterization of shape memory polymer blends for biomedical implantations journal September 1994
Use of Tissue-Type Plasminogen Activator for Acute Ischemic Stroke: The Cleveland Area Experience journal March 2000
The Greater Cincinnati/Northern Kentucky Stroke Study: Preliminary First-Ever and Total Incidence Rates of Stroke Among Blacks journal February 1998

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