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Mitochondrial ADCK3 Employs an Atypical Protein Kinase-like Fold to Enable Coenzyme Q Biosynthesis

Journal Article · · Molecular Cell

Abstract not provided

Research Organization:
Advanced Photon Source (APS), Argonne National Laboratory (ANL), Argonne, IL (US)
Sponsoring Organization:
NIH
OSTI ID:
1498377
Journal Information:
Molecular Cell, Journal Name: Molecular Cell Journal Issue: 1 Vol. 57; ISSN 1097-2765
Publisher:
Cell Press - Elsevier
Country of Publication:
United States
Language:
ENGLISH

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Cited By (22)

Mutations in COQ8B (ADCK4) found in patients with steroid-resistant nephrotic syndrome alter COQ8B function journal December 2017
Detecting Novel Sequence Signals in Targeting Peptides Using Deep Learning posted_content January 2019
Biochemical Assessment of Coenzyme Q10 Deficiency journal March 2017
A Structurally-Validated Multiple Sequence Alignment of 497 Human Protein Kinase Domains journal December 2019
Coenzyme Q biosynthetic proteins assemble in a substrate-dependent manner into domains at ER–mitochondria contacts journal January 2019
ADCK2 Haploinsufficiency Reduces Mitochondrial Lipid Oxidation and Causes Myopathy Associated with CoQ Deficiency journal September 2019
A path to the powerhouse: systems-to-structure approaches for studying mitochondrial proteins: A Path to the Powerhouse: Systems-to-Structure Approaches journal May 2018
Phosphorylation of plastoglobular proteins inArabidopsis thaliana journal March 2016
Identification and classification of small molecule kinases: insights into substrate recognition and specificity journal January 2016
Coenzyme Q deficiency causes impairment of the sulfide oxidation pathway journal November 2016
Functional analysis of Aarf domain‐containing kinase 1 in Drosophila melanogaster journal June 2019
A Structurally-Validated Multiple Sequence Alignment of 497 Human Protein Kinase Domains journal November 2019
Biosynthesis of coenzyme Q in eukaryotes journal July 2015
Drosophila ADCK1 is critical for maintaining mitochondrial structures and functions in the muscle journal May 2019
Detecting sequence signals in targeting peptides using deep learning journal September 2019
ABC1K10a, an atypical kinase, functions in plant salt stress tolerance journal June 2020
Emerging concepts in pseudoenzyme classification, evolution, and signaling journal August 2019
Phosphoproteomics in the Age of Rapid and Deep Proteome Profiling journal November 2015
Pseudoscaffolds and anchoring proteins: the difference is in the details journal April 2017
Prospects for pharmacological targeting of pseudokinases journal March 2019
Nucleotide-binding mechanisms in pseudokinases journal January 2016
Genes and lipids that impact uptake and assimilation of exogenous coenzyme Q in Saccharomyces cerevisiae. journalarticle January 2020

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