skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Nanotube structures, methods of making nanotube structures, and methods of accessing intracellular space

Patent ·
OSTI ID:1497685

In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, embodiments of the present disclosure, in one aspect, relate to methods of making a structure including nanotubes, a structure including nanotubes, methods of delivering a fluid to a cell, methods of removing a fluid to a cell, methods of accessing intracellular space, and the like.

Research Organization:
[Select One; SLAC National Accelerator Laboratory (SLAC), Menlo Park, CA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC02-76-SF00515
Assignee:
The Board of Trustees of the Leland Stanford Junior University (Stanford, CA)
Patent Number(s):
10,150,947
Application Number:
14/991,853
OSTI ID:
1497685
Resource Relation:
Patent File Date: 2016 Jan 08
Country of Publication:
United States
Language:
English

References (96)

Gigaohm resistance membrane seals with stealth probe electrodes journal July 2010
Fluid flow increases mineralized matrix deposition in 3D perfusion culture of marrow stromal osteoblasts in a dose-dependent manner journal September 2002
Computer simulations of bilayer membranes: Self-assembly and interfacial tension journal May 1998
A Cellular Trojan Horse for Delivery of Therapeutic Nanoparticles into Tumors journal December 2007
Anaesthesia by the n-alkanes. A comparative study of nerve impulse blockage and the properties of black lipid bilayer membranes journal October 1977
Vertical nanopillars for highly localized fluorescence imaging journal February 2011
Emerging links between surface nanotechnology and endocytosis: Impact on nonviral gene delivery journal December 2010
Upregulation of a Silent Sodium Channel After Peripheral, but not Central, Nerve Injury in DRG Neurons journal November 1999
Noninvasive neuroelectronic interfacing with synaptically connected snail neurons immobilized on a semiconductor chip journal August 2001
Polymeric biomaterials journal January 2000
Microfabricated Devices for Enhanced Bioadhesive Drug Delivery: Attachment to and Small-Molecule Release Through a Cell Monolayer Under Flow journal December 2009
Cells on chips journal July 2006
Tracking Gene Expression after DNA Delivery Using Spatially Indexed Nanofiber Arrays journal July 2004
A cell nanoinjector based on carbon nanotubes journal May 2007
Nanoscale porosity in polymer films: fabrication and therapeutic applications journal January 2010
Fluidic nanotubes and devices patent-application July 2011
The molecular mechanisms of anaesthesia journal July 1977
Interfacing Silicon Nanowires with Mammalian Cells journal June 2007
Whole Genome Expression Analysis Reveals Differential Effects of TiO 2 Nanotubes on Vascular Cells journal January 2010
Hydrogels for Tissue Engineering journal July 2001
Nanomaterials: A Membrane-Based Synthetic Approach journal December 1994
Alterations in gene expression of human vascular endothelial cells associated with nanotopographic cues journal December 2010
Nanoscale patterning controls inorganic–membrane interface structure journal January 2011
Template-based synthesis of nanorod, nanowire, and nanotube arrays journal January 2008
Integrin Signaling journal August 1999
A Theoretical Study on the Diffusion Current at the Stationary Electrodes of Circular and Narrow Band Types journal January 1968
Three-Dimensional, Flexible Nanoscale Field-Effect Transistors as Localized Bioprobes journal August 2010
Electroporation for the efficient transfection of mammalian cells with DNA journal January 1987
Shear Stress Induces Endothelial Differentiation From a Murine Embryonic Mesenchymal Progenitor Cell Line journal September 2005
Neural Stimulation with a Carbon Nanotube Microelectrode Array journal September 2006
Vertical silicon nanowires as a universal platform for delivering biomolecules into living cells journal January 2010
Matrix Elasticity Directs Stem Cell Lineage Specification journal August 2006
Progress in understanding reprogramming to the induced pluripotent state journal March 2011
Synthesis and Surface Engineering of Complex Nanostructures by Atomic Layer Deposition journal November 2007
Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering journal January 2005
Sensors for Electrochemical, Electrical or Topographical Analysis patent-application September 2006
Fusion of biomimetic stealth probes into lipid bilayer cores journal March 2010
The Chemotactic Effect of Mixtures of Antibody and Antigen on Polymorphonuclear Leucocytes journal March 1962
Nanoelectrodes and Nanotips for Recording Transmembrane Currents in a Plurality of Cells patent-application September 2004
Nanotube structures, methods of making nanotube structures, and methods of accessing intracellular space patent February 2016
Non-invasive method of electroporation mediated by carbon nanotubes and device for putting the method into practice patent-application February 2010
Relationship between blood flow direction and endothelial cell orientation at arterial branch sites in rabbits and mice. journal April 1981
Generation of Solution and Surface Gradients Using Microfluidic Systems journal October 2000
Generation of Gradients Having Complex Shapes Using Microfluidic Networks journal March 2001
The origins and the future of microfluidics journal July 2006
Neutral particle nanopatterning for nonplanar multimodal neural probes patent-application August 2011
The Gap Junction Communication Channel journal February 1996
Nerve-growth-factor-dependent neurite outgrowth assay; a research model for chemotherapy-induced neuropathy journal November 1995
Patterned Protein Layers on Solid Substrates by Thin Stamp Microcontact Printing journal February 1998
Synthetic DNA delivery systems journal January 2000
Molecular characterization of mitochondrial apoptosis-inducing factor journal February 1999
Organ chips and uses thereof patent-application November 2014
Polymeric Systems for Controlled Drug Release journal November 1999
New perspectives in cell adhesion: RGD and integrins journal October 1987
GeneCards Version 3: the human gene integrator journal January 2010
Cell Adhesion and Spreading Behavior on Vertically Aligned Silicon Nanowire Arrays journal November 2008
Endothelial cell polarization and chemotaxis in a microfluidic device journal January 2008
Surface-structure-regulated cell-membrane penetration by monolayer-protected nanoparticles journal May 2008
Spatially controlled cell engineering on biodegradable polymer surfaces journal November 1998
Nanofountain-Probe-Based High-Resolution Patterning and Single-Cell Injection of Functionalized Nanodiamonds journal July 2009
Method and apparatus for measuring a state variable patent April 2002
Carbon nanotube array and method for forming same patent January 2007
Stimulation of Neural Cells by Lateral Currents in Conductive Layer-by-Layer Films of Single-Walled Carbon Nanotubes journal November 2006
Semiconductor Nanowire: What’s Next? journal May 2010
Controlled release of nerve growth factor from a heparin-containing fibrin-based cell ingrowth matrix journal October 2000
Electrodeposition of nickel nanowires and nanotubes using various templates journal December 2008
Transient and Long-Lasting Openings of the Mitochondrial Permeability Transition Pore Can Be Monitored Directly in Intact Cells by Changes in Mitochondrial Calcein Fluorescence journal February 1999
A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA journal January 2003
Method of Fabricating a Three-Dimensional Nanostructure patent-application May 2007
TiO 2 nanotubes on Ti: Influence of nanoscale morphology on bone cell-materials interaction journal June 2009
Potent antibody therapeutics by design journal April 2006
Biomolecular gradients in cell culture systems journal January 2008
Microfluidic “jets” for generating steady-state gradients of soluble molecules on open surfaces journal September 2006
The stem-cell niche as an entity of action journal June 2006
Probe Arrangement patent-application December 2008
Device for transporting small volumes of a fluid, in particular a micropump or microvalve patent-application May 2013
Intracellular Molecular Delivery Based on Nanostructure Injectors patent-application October 2012
Role of Titanium Surface Topography and Surface Wettability on Focal Adhesion Kinase Mediated Signaling in Fibroblasts journal May 2011
Nanopipette apparatus for manipulating cells patent-application September 2012
Devices and methods for programmable microscale manipulation of fluids patent December 2006
Generation of Complex, Static Solution Gradients in Microfluidic Channels journal April 2006
Nanotechnology and Cancer journal February 2008
Role of laminin and basement membrane in the morphological differentiation of human endothelial cells into capillary-like structures journal October 1988
Nano Wheat Fields Prepared by Plasma-Etching Gold Nanowire-Containing Membranes journal June 2003
Direct cell reprogramming is a stochastic process amenable to acceleration journal November 2009
Ferromagnetic nanotubes by atomic layer deposition in anodic alumina membranes journal May 2007
Quantum Dots for Live Cells, in Vivo Imaging, and Diagnostics journal January 2005
Systems and methods for rapidly changing the solution environment around sensors patent-application February 2012
Method and arrangement for electrically contacting an object surrounded by a membrane, using an electrode patent-application June 2010
Fabrication of Alumina Nanotubes and Nanowires by Etching Porous Alumina Membranes journal November 2002
Microcapsule Nanotube Devices for Targeted Delivery of Therapeutic Molecules patent-application August 2010
Intercellular Nanotubes Mediate Bacterial Communication journal February 2011
A three-channel microfluidic device for generating static linear gradients and its application to the quantitative analysis of bacterial chemotaxis journal January 2006
Devices and methods for long-term intracellular access patent August 2014
Fabrication of high density metallic nanowires and nanotubes for cell culture studies journal August 2011
Compositions comprising nanostructures for cell, tissue and artificial organ growth, and methods for making and using same patent-application September 2009