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I. Analysis of biological specimens by proton-induced x-ray emission spectroscopy (PIXE). II. Separation and purity of C{sub 60} and C{sub 70}

Thesis/Dissertation ·
OSTI ID:149600

This report outlines work done on the optimization of instrumental parameters and sample preparation for the analysis of biological tissue. The analysis of biological samples by PIXE provides information on interelemental interactions in tissue and body fluids. A computer program for spectrum processes and quantitation, which decomposes overlapped peaks, corrects for thick target matrix effects and calculates results without resorting to the use of standards, is explored. In part II of this dissertation, a convenient method of removing solvent from a benzene extract of graphite soot containing fullerenes using sublimation, is outlined. Separation of macroscopic quantities of the fullerenes C{sub 60} and C{sub 70} has been accomplished using a combination of selective precipitation of C{sub 60} and chromatography. C{sub 60} is selectively crystallized freezing and thawing a benzene solution of mixed fullerenes, then using the C{sub 70} enriched supernatant as starting material in the chromatographic separation of C{sub 60} and C{sub 70}. In the separation scheme, a bed of modified silica sorbent is charged with the fullerene mixture and the fullerenes are eluted using a hexanes/THF mobile phase. The methods of UV-Visible and infrared spectroscopy, as well as high performance liquid chromatography (HPLC) are evaluated for their ability to determine the purity of a C{sub 60} or C{sub 70} sample.

Research Organization:
Arizona Univ., Tucson, AZ (United States)
OSTI ID:
149600
Country of Publication:
United States
Language:
English

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