Microscale and Nanoscale Electrophotonic Diagnostic Devices

Fu, Kaiyu; Xu, Wei; Hu, Jiayun; Lopez, Arielle; Bohn, Paul W.

doi:10.1101/cshperspect.a034249

Title: Microscale and Nanoscale Electrophotonic Diagnostic Devices

Journal Article · Mon Aug 13 00:00:00 EDT 2018 · Cold Spring Harbor Perspectives in Medicine

DOI:https://doi.org/10.1101/cshperspect.a034249· OSTI ID:1494119

Fu, Kaiyu ^[1]; Xu, Wei ^[2]; Hu, Jiayun ^[1]; Lopez, Arielle ^[1]; Bohn, Paul W. ^[1]

Univ. of Notre Dame, Notre Dame, IN (United States)
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

Detecting and identifying infectious agents and potential pathogens in complex environments and characterizing their mode of action is a critical need. Traditional diagnostics have targeted a single characteristic, e.g. spectral response, surface receptor, mass, intrinsic conductivity, etc. However, advances in detection technologies have identified emerging approaches in which multiple modes of action are combined to obtain enhanced performance characteristics. Particularly appealing in this regard, electrophotonic devices capable of coupling light to electron translocation have experienced rapid recent growth and offer significant advantages for diagnostics. In this chapter, we explore three specific promising approaches that combine electronics and photonics: (a) assays based on closed bipolar electrochemistry coupling electron transfer to color or fluorescence (b) sensors based on localized surface plasmon resonances, and (c) emerging nanophotonics approaches, such as those based on zero-mode waveguides and metamaterials.

View Accepted Manuscript (DOE)

Cite

Export

Save

Research Organization:: Univ. of Notre Dame, IN (United States)

Sponsoring Organization:: USDOE

Grant/Contract Number:: FG02-07ER15851

OSTI ID:: 1494119

Journal Information:: Cold Spring Harbor Perspectives in Medicine, Vol. 10, Issue 7; ISSN 2157-1422

Publisher:: Cold Spring Harbor Laboratory PressCopyright Statement

Country of Publication:: United States

Language:: English

Citation Metrics:

Cited by: 1 work

Citation information provided by
Web of Science

References (90)

Coupling of Independent Electrochemical Reactions and Fluorescence at Closed Bipolar Interdigitated Electrode Arrays Xu, Wei; Ma, Chaoxiong; Bohn, Paul W. ChemElectroChem, Vol. 3, Issue 3 https://doi.org/10.1002/celc.201500366	journal	October 2015
Utility of aptamer-fluorescence in situ hybridization for rapid detection of Pseudomonas aeruginosa Wang, K. -Y.; Zeng, Y. -L.; Yang, X. -Y. European Journal of Clinical Microbiology & Infectious Diseases, Vol. 30, Issue 2 https://doi.org/10.1007/s10096-010-1074-0	journal	October 2010
Visual Electrochemiluminescence Detection of Cancer Biomarkers on a Closed Bipolar Electrode Array Chip Wu, Mei-Sheng; Liu, Zhen; Shi, Hai-Wei Analytical Chemistry, Vol. 87, Issue 1 https://doi.org/10.1021/ac502989f	journal	December 2014
Mesoscopic Concentration Fluctuations in a Fluidic Nanocavity Detected by Redox Cycling Zevenbergen, Marcel A. G.; Krapf, Diego; Zuiddam, Marc R. Nano Letters, Vol. 7, Issue 2 https://doi.org/10.1021/nl062571g	journal	February 2007
A rapid-response ultrasensitive biosensor for influenza virus detection using antibody modified boron-doped diamond Nidzworski, Dawid; Siuzdak, Katarzyna; Niedziałkowski, Paweł Scientific Reports, Vol. 7, Issue 1 https://doi.org/10.1038/s41598-017-15806-7	journal	November 2017
Selective Capture and Identification of Pathogenic Bacteria Using an Immobilized Siderophore Doorneweerd, Derek D.; Henne, Walter A.; Reifenberger, Ronald G. Langmuir, Vol. 26, Issue 19 https://doi.org/10.1021/la101962w	journal	October 2010
Bipolar Electrochemical Mechanism for the Propulsion of Catalytic Nanomotors in Hydrogen Peroxide Solutions ^† Wang, Yang; Hernandez, Rose M.; Bartlett, David J. Langmuir, Vol. 22, Issue 25 https://doi.org/10.1021/la0615950	journal	December 2006
A Renewable Display Platform Based on the Bipolar Electrochromic Electrode Zhang, Xiaowei; Shang, Changshuai; Gu, Wenlin ChemElectroChem, Vol. 3, Issue 3 https://doi.org/10.1002/celc.201500282	journal	August 2015
Sensitive Electrochemiluminescence Detection of c-Myc mRNA in Breast Cancer Cells on a Wireless Bipolar Electrode Wu, Mei-Sheng; Qian, Guang-sheng; Xu, Jing-Juan Analytical Chemistry, Vol. 84, Issue 12 https://doi.org/10.1021/ac3009912	journal	May 2012
Real-Time DNA Sequencing from Single Polymerase Molecules Eid, John; Fehr, Adrian; Gray, Jeremy Science, Vol. 323, Issue 5910, p. 133-138 https://doi.org/10.1126/science.1162986	journal	January 2009
Responsive Photonic Crystal Carbohydrate Hydrogel Sensor Materials for Selective and Sensitive Lectin Protein Detection Cai, Zhongyu; Sasmal, Aniruddha; Liu, Xinyu ACS Sensors, Vol. 2, Issue 10 https://doi.org/10.1021/acssensors.7b00426	journal	October 2017
Nanosphere lithography: A materials general fabrication process for periodic particle array surfaces Hulteen, John C.; Van Duyne, Richard P. Journal of Vacuum Science & Technology A: Vacuum, Surfaces, and Films, Vol. 13, Issue 3, p. 1553-1558 https://doi.org/10.1116/1.579726	journal	May 1995
Paper-based microfluidic point-of-care diagnostic devices Yetisen, Ali Kemal; Akram, Muhammad Safwan; Lowe, Christopher R. Lab on a Chip, Vol. 13, Issue 12 https://doi.org/10.1039/c3lc50169h	journal	January 2013
“Fluidic batteries” as low-cost sources of power in paper-based microfluidic devices Thom, Nicole K.; Yeung, Kimy; Pillion, Marley B. Lab on a Chip, Vol. 12, Issue 10 https://doi.org/10.1039/c2lc40126f	journal	January 2012
Whole-Cell Pseudomonas aeruginosa Localized Surface Plasmon Resonance Aptasensor Hu, Jiayun; Fu, Kaiyu; Bohn, Paul W. Analytical Chemistry, Vol. 90, Issue 3 https://doi.org/10.1021/acs.analchem.7b04800	journal	January 2018
Whole-cell detection of live lactobacillus acidophilus on aptamer-decorated porous silicon biosensors Urmann, K.; Arshavsky-Graham, S.; Walter, J. G. The Analyst, Vol. 141, Issue 18 https://doi.org/10.1039/C6AN00810K	journal	January 2016
New biochip technology for label-free detection of pathogens and their toxins Grow, Ann E.; Wood, Laurie L.; Claycomb, Johanna L. Journal of Microbiological Methods, Vol. 53, Issue 2, p. 221-233 https://doi.org/10.1016/S0167-7012(03)00026-5	journal	May 2003
Optical Biosensor for Monitoring Microbial Cells Watts, Helen J.; Lowe, Christopher R.; Pollard-Knight, Denise V. Analytical Chemistry, Vol. 66, Issue 15 https://doi.org/10.1021/ac00087a010	journal	August 1994
Ultrafast Dynamics of Flavins in Five Redox States Kao, Ya-Ting; Saxena, Chaitanya; He, Ting-Fang Journal of the American Chemical Society, Vol. 130, Issue 39 https://doi.org/10.1021/ja8045469	journal	October 2008
Paper-Based Electrochemical Sensing Platform with Integral Battery and Electrochromic Read-Out Liu, Hong; Crooks, Richard M. Analytical Chemistry, Vol. 84, Issue 5 https://doi.org/10.1021/ac203457h	journal	February 2012
Full-Featured Electrochemiluminescence Sensing Platform Based on the Multichannel Closed Bipolar System Zhang, Xiaowei; Li, Jing; Jia, Xiaofang Analytical Chemistry, Vol. 86, Issue 11 https://doi.org/10.1021/ac501246k	journal	May 2014
A Microarray Immunoassay for Simultaneous Detection of Proteins and Bacteria Delehanty, James B.; Ligler, Frances S. Analytical Chemistry, Vol. 74, Issue 21 https://doi.org/10.1021/ac025631l	journal	November 2002
Colorimetric plasmon sensors with multilayered metallic nanoparticle sheets Shinohara, Shuhei; Tanaka, Daisuke; Okamoto, Koichi Physical Chemistry Chemical Physics, Vol. 17, Issue 28 https://doi.org/10.1039/C5CP02564H	journal	January 2015
Zero-Mode Waveguides for Single-Molecule Analysis at High Concentrations Levene, M. J. Science, Vol. 299, Issue 5607 https://doi.org/10.1126/science.1079700	journal	January 2003
A MEMS based amperometric detector for E. Coli bacteria using self-assembled monolayers Gau, Jen-Jr; Lan, Esther H.; Dunn, Bruce Biosensors and Bioelectronics, Vol. 16, Issue 9-12 https://doi.org/10.1016/S0956-5663(01)00216-0	journal	December 2001
Coupled Electrochemical Reactions at Bipolar Microelectrodes and Nanoelectrodes Guerrette, Joshua P.; Oja, Stephen M.; Zhang, Bo Analytical Chemistry, Vol. 84, Issue 3 https://doi.org/10.1021/ac2028672	journal	January 2012
Ultrasensitive detection and characterization of biomolecules using superchiral fields Hendry, E.; Carpy, T.; Johnston, J. Nature Nanotechnology, Vol. 5, Issue 11 https://doi.org/10.1038/nnano.2010.209	journal	October 2010
A label-free, microfluidics and interdigitated array microelectrode-based impedance biosensor in combination with nanoparticles immunoseparation for detection of Escherichia coli O157:H7 in food samples Varshney, Madhukar; Li, Yanbin; Srinivasan, Balaji Sensors and Actuators B: Chemical, Vol. 128, Issue 1 https://doi.org/10.1016/j.snb.2007.03.045	journal	December 2007
New insights into the nuclear structure in neutron-rich 112,114,115,116,117,118Pd Luo, Y. X.; Rasmussen, J. O.; Hamilton, J. H. Nuclear Physics A, Vol. 919 https://doi.org/10.1016/j.nuclphysa.2013.10.002	journal	December 2013
Array biosensor for detection of biohazards Rowetaitt, C. Biosensors and Bioelectronics, Vol. 14, Issue 10-11 https://doi.org/10.1016/S0956-5663(99)00052-4	journal	January 2000
Portable and Visual Electrochemical Sensor Based on the Bipolar Light Emitting Diode Electrode Zhang, Xiaowei; Chen, Chaogui; Yin, Jianyuan Analytical Chemistry, Vol. 87, Issue 9 https://doi.org/10.1021/acs.analchem.5b01018	journal	April 2015
Electrochromic Sensor for Multiplex Detection of Metabolites Enabled by Closed Bipolar Electrode Coupling Xu, Wei; Fu, Kaiyu; Bohn, Paul W. ACS Sensors, Vol. 2, Issue 7 https://doi.org/10.1021/acssensors.7b00292	journal	July 2017
Sensitive Electrochemiluminescence Biosensor Based on Au-ITO Hybrid Bipolar Electrode Amplification System for Cell Surface Protein Detection Wu, Mei-Sheng; Yuan, Da-Jing; Xu, Jing-Juan Analytical Chemistry, Vol. 85, Issue 24 https://doi.org/10.1021/ac402889z	journal	November 2013
Siderophore-Based Iron Acquisition and Pathogen Control Miethke, M.; Marahiel, M. A. Microbiology and Molecular Biology Reviews, Vol. 71, Issue 3 https://doi.org/10.1128/MMBR.00012-07	journal	September 2007
Bipolar Electrochemistry Fosdick, Stephen E.; Knust, Kyle N.; Scida, Karen Angewandte Chemie International Edition, Vol. 52, Issue 40 https://doi.org/10.1002/anie.201300947	journal	July 2013
Imaging Transient Formation of Diffusion Layers with Fluorescence-Enabled Electrochemical Microscopy Oja, Stephen M.; Zhang, Bo Analytical Chemistry, Vol. 86, Issue 24 https://doi.org/10.1021/ac5035715	journal	November 2014
A Nanoscale Optical Biosensor: Sensitivity and Selectivity of an Approach Based on the Localized Surface Plasmon Resonance Spectroscopy of Triangular Silver Nanoparticles Haes, Amanda J.; Van Duyne, Richard P. Journal of the American Chemical Society, Vol. 124, Issue 35, p. 10596-10604 https://doi.org/10.1021/ja020393x	journal	September 2002
Biosensors: sense and sensibility Turner, Anthony P. F. Chemical Society Reviews, Vol. 42, Issue 8 https://doi.org/10.1039/c3cs35528d	journal	January 2013
Cell-free DNA in the blood as a solid tumor biomarker—A critical appraisal of the literature Jung, Klaus; Fleischhacker, Michael; Rabien, Anja Clinica Chimica Acta, Vol. 411, Issue 21-22 https://doi.org/10.1016/j.cca.2010.07.032	journal	November 2010
Paper-Based Bipolar Electrode Electrochemiluminescence Switch for Label-Free and Sensitive Genetic Detection of Pathogenic Bacteria Liu, Hongxing; Zhou, Xiaoming; Liu, Weipeng Analytical Chemistry, Vol. 88, Issue 20 https://doi.org/10.1021/acs.analchem.6b02772	journal	September 2016
Formation of Molecular Gradients on Bipolar Electrodes Ulrich, Christian; Andersson, Olof; Nyholm, Leif Angewandte Chemie International Edition, Vol. 47, Issue 16 https://doi.org/10.1002/anie.200705824	journal	April 2008
A guide to aid the selection of diagnostic tests Kosack, Cara S.; Page, Anne-Laure; Klatser, Paul R. Bulletin of the World Health Organization, Vol. 95, Issue 9 https://doi.org/10.2471/BLT.16.187468	journal	June 2017
Single-Molecule Spectroscopy Studies of Molecular Dynamics in Chemical and Biological Systems* Lu, H. Peter; Xie, X. Sunney Zeitschrift für Physikalische Chemie, Vol. 212, Issue Part_1 https://doi.org/10.1524/zpch.1999.212.Part_1.059	journal	January 1999
Self-induced redox cycling coupled luminescence on nanopore recessed disk-multiscale bipolar electrodes Ma, Chaoxiong; Zaino III, Lawrence P.; Bohn, Paul W. Chemical Science, Vol. 6, Issue 5 https://doi.org/10.1039/C5SC00433K	journal	January 2015
Electrical detection of pathogenic bacteria via immobilized antimicrobial peptides Mannoor, M. S.; Zhang, S.; Link, A. J. Proceedings of the National Academy of Sciences, Vol. 107, Issue 45 https://doi.org/10.1073/pnas.1008768107	journal	October 2010
Multiplex PCR: Optimization and Application in Diagnostic Virology Elnifro, Elfath M.; Ashshi, Ahmed M.; Cooper, Robert J. Clinical Microbiology Reviews, Vol. 13, Issue 4 https://doi.org/10.1128/CMR.13.4.559	journal	October 2000
Localized Surface Plasmon Resonance Spectroscopy and Sensing Willets, Katherine A.; Van Duyne, Richard P. Annual Review of Physical Chemistry, Vol. 58, Issue 1 https://doi.org/10.1146/annurev.physchem.58.032806.104607	journal	May 2007
Microbial Iron Acquisition: Marine and Terrestrial Siderophores Sandy, Moriah; Butler, Alison Chemical Reviews, Vol. 109, Issue 10 https://doi.org/10.1021/cr9002787	journal	October 2009
Bipolar Electrodes for Rapid Screening of Electrocatalysts Fosdick, Stephen E.; Crooks, Richard M. Journal of the American Chemical Society, Vol. 134, Issue 2 https://doi.org/10.1021/ja210354m	journal	December 2011
Programmable diagnostic devices made from paper and tape Martinez, Andres W.; Phillips, Scott T.; Nie, Zhihong Lab on a Chip, Vol. 10, Issue 19 https://doi.org/10.1039/c0lc00021c	journal	January 2010
Bipolar Electrode Focusing: The Effect of Current and Electric Field on Concentration Enrichment Perdue, Robbyn K.; Laws, Derek R.; Hlushkou, Dzmitry Analytical Chemistry, Vol. 81, Issue 24, p. 10149-10155 https://doi.org/10.1021/ac901913r	journal	December 2009
Cholesterol Self-Powered Biosensor Sekretaryova, Alina N.; Beni, Valerio; Eriksson, Mats Analytical Chemistry, Vol. 86, Issue 19 https://doi.org/10.1021/ac501699p	journal	September 2014
Paper-based electrochemiluminescence bipolar conductivity sensing mechanism: A critical supplement for the bipolar system Zhang, Xiaowei; Zhai, Qingfeng; Xu, Li Journal of Electroanalytical Chemistry, Vol. 781 https://doi.org/10.1016/j.jelechem.2016.07.009	journal	November 2016
A Conformation- and Ion-Sensitive Plasmonic Biosensor Hall, W. Paige; Modica, Justin; Anker, Jeffrey Nano Letters, Vol. 11, Issue 3 https://doi.org/10.1021/nl103994w	journal	March 2011
Wafer-Scale Fabrication of Plasmonic Crystals from Patterned Silicon Templates Prepared by Nanosphere Lithography Hall, Anthony Shoji; Friesen, Stuart A.; Mallouk, Thomas E. Nano Letters, Vol. 13, Issue 6 https://doi.org/10.1021/nl400755a	journal	May 2013
A Large-Scale, Wireless Electrochemical Bipolar Electrode Microarray Chow, Kwok-Fan; Mavré, François; Crooks, John A. Journal of the American Chemical Society, Vol. 131, Issue 24 https://doi.org/10.1021/ja902683f	journal	June 2009
Electrochemical Sensors and Biosensors Kimmel, Danielle W.; LeBlanc, Gabriel; Meschievitz, Mika E. Analytical Chemistry, Vol. 84, Issue 2 https://doi.org/10.1021/ac202878q	journal	November 2011
Aptamer in Bioanalytical Applications Iliuk, Anton B.; Hu, Lianghai; Tao, W. Andy Analytical Chemistry, Vol. 83, Issue 12 https://doi.org/10.1021/ac201057w	journal	June 2011
Visual Color-Switch Electrochemiluminescence Biosensing of Cancer Cell Based on Multichannel Bipolar Electrode Chip Zhang, Huai-Rong; Wang, Yin-Zhu; Zhao, Wei Analytical Chemistry, Vol. 88, Issue 5 https://doi.org/10.1021/acs.analchem.5b04716	journal	February 2016
Bipolar Electrodes: A Useful Tool for Concentration, Separation, and Detection of Analytes in Microelectrochemical Systems Mavré, François; Anand, Robbyn K.; Laws, Derek R. Analytical Chemistry, Vol. 82, Issue 21 https://doi.org/10.1021/ac101262v	journal	November 2010
In Vitro Selection of Functional Nucleic Acids Wilson, David S.; Szostak, Jack W. Annual Review of Biochemistry, Vol. 68, Issue 1 https://doi.org/10.1146/annurev.biochem.68.1.611	journal	June 1999
Simple Strategy for Rapid and Sensitive Detection of Avian Influenza A H7N9 Virus Based on Intensity-Modulated SPR Biosensor and New Generated Antibody Chang, Ying-Feng; Wang, Wen-Hung; Hong, Yi-Wei Analytical Chemistry, Vol. 90, Issue 3 https://doi.org/10.1021/acs.analchem.7b03934	journal	January 2018
LSPR Biosensor Signal Enhancement Using Nanoparticle−Antibody Conjugates Hall, W. Paige; Ngatia, Salome N.; Van Duyne, Richard P. The Journal of Physical Chemistry C, Vol. 115, Issue 5 https://doi.org/10.1021/jp106912p	journal	December 2010
Rapid tests for sexually transmitted infections (STIs): the way forward Peeling, R. W.; Holmes, K. K.; Mabey, D. Sexually Transmitted Infections, Vol. 82, Issue suppl_5 https://doi.org/10.1136/sti.2006.024265	journal	December 2006
Electrochemical DNA Biosensor Based on a Tetrahedral Nanostructure Probe for the Detection of Avian Influenza A (H7N9) Virus Dong, Shibiao; Zhao, Rongtao; Zhu, Jiangong ACS Applied Materials & Interfaces, Vol. 7, Issue 16 https://doi.org/10.1021/acsami.5b01438	journal	April 2015
Ultrasensitive Impedimetric Lectin Biosensors with Efficient Antifouling Properties Applied in Glycoprofiling of Human Serum Samples Bertok, Tomas; Klukova, Ludmila; Sediva, Alena Analytical Chemistry, Vol. 85, Issue 15 https://doi.org/10.1021/ac401281t	journal	July 2013
Single-shot detection of bacterial endospores via coherent Raman spectroscopy Pestov, D.; Wang, X.; Ariunbold, G. O. Proceedings of the National Academy of Sciences, Vol. 105, Issue 2 https://doi.org/10.1073/pnas.0710427105	journal	January 2008
Optical Biosensing of Bacteria and Bacterial Communities Hu, Jiayun; Bohn, Paul W. Journal of Analysis and Testing, Vol. 1, Issue 1 https://doi.org/10.1007/s41664-017-0002-z	journal	January 2017
Toward Single-Enzyme Molecule Electrochemistry: [NiFe]-Hydrogenase Protein Film Voltammetry at Nanoelectrodes Hoeben, Freek J. M.; Meijer, F. Stefan; Dekker, Cees ACS Nano, Vol. 2, Issue 12 https://doi.org/10.1021/nn800518d	journal	November 2008
Metering the Capillary-Driven Flow of Fluids in Paper-Based Microfluidic Devices Noh, Hyeran; Phillips, Scott T. Analytical Chemistry, Vol. 82, Issue 10 https://doi.org/10.1021/ac100431y	journal	May 2010
Long period grating based biosensor for the detection of Escherichia coli bacteria Tripathi, Saurabh Mani; Bock, Wojtek J.; Mikulic, Predrag Biosensors and Bioelectronics, Vol. 35, Issue 1 https://doi.org/10.1016/j.bios.2012.03.006	journal	May 2012
Chemistry and biology of siderophores Hider, Robert C.; Kong, Xiaole Natural Product Reports, Vol. 27, Issue 5 https://doi.org/10.1039/b906679a	journal	January 2010
New Approaches to Sepsis: Molecular Diagnostics and Biomarkers Reinhart, K.; Bauer, M.; Riedemann, N. C. Clinical Microbiology Reviews, Vol. 25, Issue 4 https://doi.org/10.1128/CMR.00016-12	journal	October 2012
Electrochemical Methods for the Analysis of Clinically Relevant Biomolecules Labib, Mahmoud; Sargent, Edward H.; Kelley, Shana O. Chemical Reviews, Vol. 116, Issue 16 https://doi.org/10.1021/acs.chemrev.6b00220	journal	July 2016
Single Molecule Electrochemical Detection in Aqueous Solutions and Ionic Liquids Byers, Joshua C.; Paulose Nadappuram, Binoy; Perry, David Analytical Chemistry, Vol. 87, Issue 20 https://doi.org/10.1021/acs.analchem.5b02569	journal	October 2015
Preliminary studies and potential applications of localized surface plasmon resonance spectroscopy in medical diagnostics Haes, Amanda J.; Duyne, Richard P. Van Expert Review of Molecular Diagnostics, Vol. 4, Issue 4 https://doi.org/10.1586/14737159.4.4.527	journal	July 2004
Next-generation DNA sequencing Shendure, Jay; Ji, Hanlee Nature Biotechnology, Vol. 26, Issue 10 https://doi.org/10.1038/nbt1486	journal	October 2008
Electrochemistry at single molecule occupancy in nanopore-confined recessed ring-disk electrode arrays Fu, Kaiyu; Han, Donghoon; Ma, Chaoxiong Faraday Discussions, Vol. 193 https://doi.org/10.1039/C6FD00062B	journal	January 2016
Single occupancy spectroelectrochemistry of freely diffusing flavin mononucleotide in zero-dimensional nanophotonic structures Zaino, Lawrence P.; Grismer, Dane A.; Han, Donghoon Faraday Discussions, Vol. 184 https://doi.org/10.1039/C5FD00072F	journal	January 2015
Lectin-Based Affinity Capture for MALDI-MS Analysis of Bacteria Bundy, Jonathan; Fenselau, Catherine Analytical Chemistry, Vol. 71, Issue 7 https://doi.org/10.1021/ac981119h	journal	April 1999
Electrochemical Correlation Spectroscopy in Nanofluidic Cavities Zevenbergen, Marcel A. G.; Singh, Pradyumna S.; Goluch, Edgar D. Analytical Chemistry, Vol. 81, Issue 19 https://doi.org/10.1021/ac9014885	journal	October 2009
Bipolar Electrochemistry: From Materials Science to Motion and Beyond Loget, Gabriel; Zigah, Dodzi; Bouffier, Laurent Accounts of Chemical Research, Vol. 46, Issue 11 https://doi.org/10.1021/ar400039k	journal	May 2013
Quantitative and simultaneous detection of four foodborne bacterial pathogens with a multi-channel SPR sensor Taylor, Allen D.; Ladd, Jon; Yu, Qiuming Biosensors and Bioelectronics, Vol. 22, Issue 5 https://doi.org/10.1016/j.bios.2006.03.012	journal	December 2006
Bipolar Electrodes with 100% Current Efficiency for Sensors Zhang, Xiaowei; Zhai, Qingfeng; Xing, Huanhuan ACS Sensors, Vol. 2, Issue 3 https://doi.org/10.1021/acssensors.7b00031	journal	March 2017
A low-cost, ultraflexible cloth-based microfluidic device for wireless electrochemiluminescence application Liu, Min; Liu, Rui; Wang, Dan Lab on a Chip, Vol. 16, Issue 15 https://doi.org/10.1039/C6LC00289G	journal	January 2016
Microfluidic diagnostic technologies for global public health Yager, Paul; Edwards, Thayne; Fu, Elain Nature, Vol. 442, Issue 7101, p. 412-418 https://doi.org/10.1038/nature05064	journal	July 2006
Closed bipolar electrode-enabled dual-cell electrochromic detectors for chemical sensing Xu, Wei; Fu, Kaiyu; Ma, Chaoxiong The Analyst, Vol. 141, Issue 21 https://doi.org/10.1039/C6AN01415A	journal	January 2016
Steady-State Voltammetry of a Microelectrode in a Closed Bipolar Cell Cox, Jonathan T.; Guerrette, Joshua P.; Zhang, Bo Analytical Chemistry, Vol. 84, Issue 20 https://doi.org/10.1021/ac302219p	journal	October 2012
Enzyme Biosensor Based on Plasma-Polymerized Film-Covered Carbon Nanotube Layer Grown Directly on A Flat Substrate Muguruma, Hitoshi; Hoshino, Tatsuya; Matsui, Yasunori ACS Applied Materials & Interfaces, Vol. 3, Issue 7 https://doi.org/10.1021/am200342q	journal	June 2011
Point-of-Care Diagnostics for Global Health Yager, Paul; Domingo, Gonzalo J.; Gerdes, John Annual Review of Biomedical Engineering, Vol. 10, Issue 1 https://doi.org/10.1146/annurev.bioeng.10.061807.160524	journal	August 2008

Similar Records

Single Entity Electrochemistry in Nanopore Electrode Arrays: Ion Transport Meets Electron Transfer in Confined Geometries

Journal Article · Tue Jan 28 00:00:00 EST 2020 · Accounts of Chemical Research · OSTI ID:1494119

Fu, Kaiyu; Kwon, Seung-Ryong; Han, Donghoon; +1 more

Tunable optical metamaterial-based sensors enabled by closed bipolar electrochemistry

Journal Article · Tue Jan 01 00:00:00 EST 2019 · Analyst · OSTI ID:1494119

Crouch, Garrison M.; Oh, Christiana; Fu, Kaiyu; +1 more

In Situ Analytical Electron Microscopy for Probing Nanoscale Electrochemistry

Journal Article · Mon Oct 31 00:00:00 EDT 2011 · The Electrochemical Society Interface · OSTI ID:1494119

Graetz, J; Meng, Y S; McGilvray, T; +5 more

Related Subjects

60 APPLIED LIFE SCIENCES

Title: Microscale and Nanoscale Electrophotonic Diagnostic Devices

Citation Formats

References (90)

Similar Records

Related Subjects