Methods for the synthesis of olefins and derivatives

Burk, Mark J.; Pharkya, Priti; Van Dien, Stephen J.; Burgard, Anthony P.; Schilling, Christophe H.

Methods for the synthesis of olefins and derivatives

Patent · 25 September 2018

OSTI ID:1484241

Burk, Mark J.; Pharkya, Priti; Van Dien, Stephen J.; Burgard, Anthony P.; Schilling, Christophe H.

The invention provides a method of producing acrylic acid. The method includes contacting fumaric acid with a sufficient amount of ethylene in the presence of a cross-metathesis transformation catalyst to produce about two moles of acrylic acid per mole of fumaric acid. Also provided is an acrylate ester. The method includes contacting fumarate diester with a sufficient amount of ethylene in the presence of a cross-metathesis transformation catalyst to produce about two moles of acrylate ester per mole of fumarate diester. An integrated process for process for producing acrylic acid or acrylate ester is provided which couples bioproduction of fumaric acid with metathesis transformation. An acrylic acid and an acrylate ester production also is provided.

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Research Organization:: Genomatica, Inc., San Diego, CA (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: FG02-06ER84536; FG02-07ER84865

Assignee:: Genomatica, Inc. (San Diego, CA)

Patent Number(s):: 10,081,587

Application Number:: 15/182,245

OSTI ID:: 1484241

Country of Publication:: United States

Language:: English

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