Investigation of the physical aspects of beta imaging probes using scintillating fibers and visible light photon counters

Journal Article · Tue Aug 01 04:00:00 EDT 1995 · IEEE Transactions on Nuclear Science

DOI:https://doi.org/10.1109/23.467855· OSTI ID:148085

MacDonald, L R; Tornai, M P; Levin, C S; Park, J; Atac, M; Cline, D B; Hoffman, E J ^[1]

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1. Univ. of California, Los Angeles, CA (United States)

The authors are developing a hand-held imaging probe intended for intra-operative use. This probe is to be used after the bulk of a tumor has been removed. It will locate residual malignant tissue labeled by a pre-operative injection of a tumor-seeking radiopharmaceutical. The device presented here is a prototype system that consists of a 4 {times} 8 array of 925{mu}m diameter plastic scintillating fibers. The imaging array is coupled to Visible Light Photon Counters (VLPCs) via 2 meters of optical fiber. The authors have obtained an intrinsic spatial resolution of < 1.0 mm With a highly collimated beta source, and a 2.0 mm resolution with a 1 mm, uncollimated source. Standard deviations of the relative gain and sensitivity over the 32 imaging elements were found to be 9.6% and 11.7% of the mean, respectively.

• OSTI ID: 148085
• Report Number(s): CONF-941061--
• Journal Information: IEEE Transactions on Nuclear Science, Journal Name: IEEE Transactions on Nuclear Science Journal Issue: 4Pt1 Vol. 42; ISSN IETNAE; ISSN 0018-9499
• Country of Publication: United States
• Language: English

Related Subjects

44 INSTRUMENTATION
INCLUDING NUCLEAR AND PARTICLE DETECTORS
55 BIOLOGY AND MEDICINE
BASIC STUDIES
DESIGN
DIAGNOSIS
DIAGNOSTIC USES
IMAGE PROCESSING
NEOPLASMS
PERFORMANCE
RADIOPHARMACEUTICALS
SCINTILLATION COUNTERS
SENSITIVITY ANALYSIS