Energy window optimization in simultaneous technetium-99m TCT and thallium-201 SPECT data acquisition

Journal Article · Tue Aug 01 04:00:00 EDT 1995 · IEEE Transactions on Nuclear Science

OSTI ID:148071

Li, J; Tsui, B M.W.; Frey, E C ^[1]; Welch, A; Gullberg, G T ^[2]

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1. Univ. of North Carolina, Chapel Hill, NC (United States). Dept. of Biomedical Engineering
2. Univ. of Utah, Salt Lake City, UT (United States). Dept. of Radiology

In simultaneous Tc-99m TCT and Tl-201 SPECT data acquisition, the emission images are degraded by not only scatter from the emission source, but also cross-contamination from the transmission photons. Also, the transmission images are degraded by scatter from the transmission source and cross-contamination from the emission photons. In this work, a criterion based on maximizing a Figure-of-Merit (FOM) was used to reduce image degradations by optimizing the position and width of the energy windows used in the data acquisition in a triple-camera fan-beam SPECT system. The FOM determines a compromise between increased detection efficiency of primary photons and reduction of scatter and cross-contamination photons. Scatter in the projection data was modeled using Monte Carlo (MC) simulation methods. Experimental studies were performed to verify the simulations and to estimate the amount of Ph x-rays and scatter in the collimator which were not modeled in the MC program. Results suggest that cross-contamination degrades the emission and transmission data. However, the contamination does not significantly alter the optimal energy window settings, which should be centered at {approximately}77 keV with a window width of {approximately}34% for detecting the Tl emission photons, and centered at 140 keV with a window width of {approximately}20% for detecting the Tc transmission photons.

• OSTI ID: 148071
• Report Number(s): CONF-941061--
• Journal Information: IEEE Transactions on Nuclear Science, Journal Name: IEEE Transactions on Nuclear Science Journal Issue: 4Pt1 Vol. 42; ISSN 0018-9499; ISSN IETNAE
• Country of Publication: United States
• Language: English

Related Subjects

55 BIOLOGY AND MEDICINE
BASIC STUDIES
EMISSION COMPUTED TOMOGRAPHY
IMAGE PROCESSING
ISOMERIC NUCLEI
MONTE CARLO METHOD
OPTIMIZATION
PERFORMANCE
SCATTERING
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
TECHNETIUM 99
THALLIUM 201