First point-spread function and x-ray phase-contrast imaging results with an 88-mm diameter single crystal

Lumpkin, Alex H.; Garson, Alfred B.; Anastasio, Mark A.

doi:10.1063/1.5027499

Title: First point-spread function and x-ray phase-contrast imaging results with an 88-mm diameter single crystal

Journal Article · Sun Jul 01 00:00:00 EDT 2018 · Review of Scientific Instruments

DOI:https://doi.org/10.1063/1.5027499· OSTI ID:1438532

Lumpkin, Alex H. ^[1]; Garson, Alfred B. ^[2]; Anastasio, Mark A. ^[2]

Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States)
Washington Univ. in St. Louis, St. Louis, MO (United States)

In this paper, we report initial demonstrations of the use of single crystals in indirect x-ray imaging with a benchtop implementation of propagation-based (PB) x-ray phase contrast imaging. Based on single Gaussian peak fits to the x-ray images, we observed a four times smaller system point-spread function (PSF) with the 50-μm thick single crystal scintillators than with the reference polycrystalline phosphor/scintillator. Fiber-optic plate depth-of-focus and Al reflective-coating aspects are also elucidated. Guided by the results from the 25-mm diameter crystal samples, we report additionally the first results with a unique 88-mm diameter single crystal bonded to a fiber optic plate and coupled to the large format CCD. Both PSF and x-ray phase contrast imaging data are quantified and presented.

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Research Organization:: Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States)

Sponsoring Organization:: USDOE Office of Science (SC), High Energy Physics (HEP)

Grant/Contract Number:: AC02-07CH11359; AC02- 07CH11359

OSTI ID:: 1438532

Alternate ID(s):: OSTI ID: 1460601

Report Number(s):: FERMILAB-PUB-18-059-AD; arXiv:1807.02170; 1674303; TRN: US1900447

Journal Information:: Review of Scientific Instruments, Vol. 89, Issue 7; ISSN 0034-6748

Publisher:: American Institute of Physics (AIP)Copyright Statement

Country of Publication:: United States

Language:: English

References (17)

Refracting Röntgen’s rays: Propagation-based x-ray phase contrast for biomedical imaging Gureyev, T. E.; Mayo, S. C.; Myers, D. E. Journal of Applied Physics, Vol. 105, Issue 10 https://doi.org/10.1063/1.3115402	journal	May 2009
High-resolution X-ray imaging CCD camera based on a thin scintillator screen Touš, J.; Blažek, K.; Pína, L. Radiation Measurements, Vol. 42, Issue 4-5 https://doi.org/10.1016/j.radmeas.2007.02.040	journal	April 2007
In-line X-ray phase-contrast lung imaging In situ with a benchtop system Garson, A. B.; Izaguirre, E. W.; Price, S. G. SPIE Medical Imaging, SPIE Proceedings https://doi.org/10.1117/12.2043936	conference	March 2014
Potential for Imaging Engineered Tissues with X-Ray Phase Contrast Appel, Alyssa; Anastasio, Mark A.; Brey, Eric M. Tissue Engineering Part B: Reviews, Vol. 17, Issue 5 https://doi.org/10.1089/ten.teb.2011.0230	journal	October 2011
Theory and preliminary experimental verification of quantitative edge illumination x-ray phase contrast tomography Hagen, C. K.; Diemoz, P. C.; Endrizzi, M. Optics Express, Vol. 22, Issue 7 https://doi.org/10.1364/oe.22.007989	journal	January 2014
Liquid-metal-jet x-ray tube technology and tomography applications Espes, Emil; Andersson, Tommy; Björnsson, Fredrik SPIE Optical Engineering + Applications, SPIE Proceedings https://doi.org/10.1117/12.2061612	conference	September 2014
Characterization of CCD-based imaging X-ray detectors for diffraction experiments Naday, I.; Ross, S.; Kanyo, M. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Vol. 347, Issue 1-3 https://doi.org/10.1016/0168-9002(94)91943-7	journal	August 1994
Hard X-Ray Phase Tomography with Low-Brilliance Sources Pfeiffer, F.; Kottler, C.; Bunk, O. Physical Review Letters, Vol. 98, Issue 10 https://doi.org/10.1103/physrevlett.98.108105	journal	March 2007
Diffraction enhanced x-ray imaging Chapman, D.; Thomlinson, W.; Johnston, R. E. Physics in Medicine and Biology, Vol. 42, Issue 11, p. 2015-2025 https://doi.org/10.1088/0031-9155/42/11/001	journal	November 1997
Comparison of two x-ray phase-contrast imaging methods with a microfocus source Zhou, T.; Lundström, U.; Thüring, T. Optics Express, Vol. 21, Issue 25 https://doi.org/10.1364/OE.21.030183	journal	January 2013
Upgrades of beam diagnostics with application to emittance-exchange experiments Lumpkin, A. H.; Johnson, A. S.; Ruan, J. Physical Review Special Topics - Accelerators and Beams, Vol. 14, Issue 6 https://doi.org/10.1103/physrevstab.14.060704	journal	June 2011
Multiple-image radiography Wernick, Miles N.; Wirjadi, Oliver; Chapman, Dean Physics in Medicine and Biology, Vol. 48, Issue 23 https://doi.org/10.1088/0031-9155/48/23/006	journal	November 2003
X-Ray Holographic Imaging of Hydrated Biological Cells in Solution Bartels, M.; Krenkel, M.; Haber, J. Physical Review Letters, Vol. 114, Issue 4 https://doi.org/10.1103/PhysRevLett.114.048103	journal	January 2015
Propagation-based phase-contrast tomography for high-resolution lung imaging with laboratory sources Krenkel, Martin; Töpperwien, Mareike; Dullin, Christian AIP Advances, Vol. 6, Issue 3 https://doi.org/10.1063/1.4943898	journal	March 2016
Characterization Of Fluorescent Screens For Imaging Applications With Mev Neutrons And Photons Berzins, G. J.; Lumpkin, A. H.; Smith, H. L. Optical Engineering, Vol. 22, Issue 5 https://doi.org/10.1117/12.7973208	journal	October 1983
On the evolution and relative merits of hard X-ray phase-contrast imaging methods Wilkins, S. W.; Nesterets, Ya. I.; Gureyev, T. E. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, Vol. 372, Issue 2010 https://doi.org/10.1098/rsta.2013.0021	journal	March 2014
X-ray phase-contrast tomosynthesis of a human ex vivo breast slice with an inverse Compton x-ray source Eggl, E.; Schleede, S.; Bech, M. EPL (Europhysics Letters), Vol. 116, Issue 6 https://doi.org/10.1209/0295-5075/116/68003	journal	December 2016

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46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY
x-rays
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single crystal scintillator
x-ray phase-contrast imaging

Title: First point-spread function and x-ray phase-contrast imaging results with an 88-mm diameter single crystal

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