Infrared tomography for diagnostic imaging of port wine stain blood vessels
Conference
·
OSTI ID:145957
- Lawrence Livermore National Lab., CA (United States)
The objective of this work is the development of Infrared Tomography (IRT) for detecting and characterizing subsurface chromophores in human skin. Characterization of cutaneous chromophores is crucial for advances in the laser treatment of pigmented lesions (e.g., port wine stain birthmarks and tatoos). Infrared tomography (IRT) uses a fast infrared focal plane array (IR-FPA) to detect temperature rises in a substrate induced by pulsed radiation. A pulsed laser is used to produce transient heating of an object. The temperature rise, due to the optical absorption of the pulsed laser light, creates an increase in infrared emission which is measured by the IR-FPA. Although the application of IRT to image subsurface cracks due to metal fatigue is a topic of great interest in the aircraft industry, the application to image subsurface chromophores in biological materials is novel. We present an image recovery method based on a constrained conjugate gradient algorithm that has obtained the first ever high quality images of port wine blood vessels.
- Research Organization:
- Lawrence Livermore National Lab., CA (United States)
- OSTI ID:
- 145957
- Report Number(s):
- CONF-9411140--Absts.; ON: DE95017252
- Country of Publication:
- United States
- Language:
- English
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