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Defining Long-Range Order and Local Disorder in Native α-Synuclein Using Residual Dipolar Couplings
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Conformational properties of α-synuclein in its free and lipid-associated states 1 1Edited by P. E. Wright
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Molecular-level secondary structure, polymorphism, and dynamics of full-length -synuclein fibrils studied by solid-state NMR
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Evidence for a Partially Folded Intermediate in α-Synuclein Fibril Formation
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Silatrane-based surface chemistry for immobilization of DNA, protein-DNA complexes and other biological materials
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Interplay of -synuclein binding and conformational switching probed by single-molecule fluorescence
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α-Synuclein Misfolding: Single Molecule AFM Force Spectroscopy Study
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Effect of Spermidine on Misfolding and Interactions of Alpha-Synuclein
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α-Synuclein: Membrane Interactions and Toxicity in Parkinson's Disease
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Direct Observation of Heterogeneous Amyloid Fibril Growth Kinetics via Two-Color Super-Resolution Microscopy
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Structural disorder of monomeric α-synuclein persists in mammalian cells
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Mutation in the -Synuclein Gene Identified in Families with Parkinson's Disease
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MedusaScore: An Accurate Force Field-Based Scoring Function for Virtual Drug Screening
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Structure and Dynamics of Micelle-bound Human -Synuclein
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Nonnative SOD1 trimer is toxic to motor neurons in a model of amyotrophic lateral sclerosis
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Visualization of Intrinsically Disordered Regions of Proteins by High-Speed Atomic Force Microscopy
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The Role of Stable α-Synuclein Oligomers in the Molecular Events Underlying Amyloid Formation
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Single Fibril Growth Kinetics of α-Synuclein
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Early Stages for Parkinson’s Development: α-Synuclein Misfolding and Aggregation
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Rapid Self-assembly of α-Synuclein Observed by In Situ Atomic Force Microscopy
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Nanoprobing of α-synuclein misfolding and aggregation with atomic force microscopy
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α-Synuclein misfolding and Parkinson's disease
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Discrete molecular dynamics studies of the folding of a protein-like model
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From The Cover: Release of long-range tertiary interactions potentiates aggregation of natively unstructured -synuclein
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Direct Detection of α-Synuclein Dimerization Dynamics: Single-Molecule Fluorescence Analysis
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Direct observation of the three regions in α-synuclein that determine its membrane-bound behaviour
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Ab Initio Folding of Proteins with All-Atom Discrete Molecular Dynamics
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High Intrinsic Mechanical Flexibility of Mouse Prion Nanofibrils Revealed by Measurements of Axial and Radial Young’s Moduli
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A novel pathway for amyloids self-assembly in aggregates at nanomolar concentration mediated by the interaction with surfaces
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Visualizing a one-way protein encounter complex by ultrafast single-molecule mixing
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α-Synuclein Misfolding Assessed with Single Molecule AFM Force Spectroscopy: Effect of Pathogenic Mutations
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The most important thing is the tail: Multitudinous functionalities of intrinsically disordered protein termini
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A Combinatorial NMR and EPR Approach for Evaluating the Structural Ensemble of Partially Folded Proteins
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To be disordered or not to be disordered: is that still a question for proteins in the cell?
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Prediction of “Aggregation-prone” and “Aggregation-susceptible” Regions in Proteins Associated with Neurodegenerative Diseases
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α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation
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NACP, A Protein Implicated in Alzheimer's Disease and Learning, Is Natively Unfolded †
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α-Synuclein-Induced Membrane Remodeling Is Driven by Binding Affinity, Partition Depth, and Interleaflet Order Asymmetry
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Structural Intermediates during α-Synuclein Fibrillogenesis on Phospholipid Vesicles
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Dynamics of Nucleosomes Assessed with Time-Lapse High-Speed Atomic Force Microscopy
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α-Synuclein in Lewy bodies
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Use of the Weighted Histogram Analysis Method for the Analysis of Simulated and Parallel Tempering Simulations
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Single Molecule AFM Force Spectroscopy Analysis of Alpha-Synuclein Misfolding
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The fold of -synuclein fibrils
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Mapping Long-Range Interactions in α-Synuclein using Spin-Label NMR and Ensemble Molecular Dynamics Simulations
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VMD: Visual molecular dynamics
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Conformational distortion in a fibril-forming oligomer arrests alpha-Synuclein fibrillation and minimizes its toxic effects
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May 2021 |
Applications of Discrete Molecular Dynamics in biology and medicine
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text
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January 2016 |
Nonnative SOD1 trimer is toxic to motor neurons in a model of amyotrophic lateral sclerosis
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text
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January 2016 |
Ab Initio Folding of Proteins with All-Atom Discrete Molecular Dynamics
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text
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January 2008 |
Direct observation of heterogeneous amyloid fibril growth kinetics via two-color super-resolution microscopy.
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text
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January 2014 |
MedusaScore: An Accurate Force Field-Based Scoring Function for Virtual Drug Screening
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text
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January 2008 |
Generalized-Ensemble Algorithms: Enhanced Sampling Techniques for Monte Carlo and Molecular Dynamics Simulations
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preprint
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January 2003 |
Discrete molecular dynamics studies of the folding of a protein-like model
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text
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January 1998 |