Ultrasensitive detection enabled by nonlinear magnetization of nanomagnetic labels

Nikitin, Max P.; Orlov, A. V.; Sokolov, I. L.; Minakov, A. A.; Nikitin, P. I.; Ding, J.; Bader, S. D.; Rozhkova, E. A.; Novosad, V.

doi:10.1039/c8nr01511b

Ultrasensitive detection enabled by nonlinear magnetization of nanomagnetic labels

Journal Article · Tue Jun 05 00:00:00 EDT 2018 · Nanoscale

DOI:https://doi.org/10.1039/c8nr01511b· OSTI ID:1466378

^[1]; ^[2]; ^[3]; ^[2]; ^[2]; ^[4]; ^[4]; ^[4]; ^[5]

Argonne National Lab. (ANL), Argonne, IL (United States); Moscow Institute of Physics and Technology, Moscow Region (Russia); Prokhorov General Physics Institute of the Russian Academy of Sciences, Moscow (Russia)
Prokhorov General Physics Institute of the Russian Academy of Sciences, Moscow (Russia)
Moscow Institute of Physics and Technology, Moscow (Russia)
Argonne National Lab. (ANL), Argonne, IL (United States)
Argonne National Lab. (ANL), Argonne, IL (United States); National Univ. of Science and Technology (MISiS), Moscow (Russia)

The magnetically soft, disk-shaped particles reveal a strong nonlinearity of the magnetization process due to irreversible transitions from the spin vortex to single-domain configuration, enabling their ultrasensitive detection in high-background environments.

View Accepted Manuscript (DOE)

Research Organization:: Argonne National Lab. (ANL), Argonne, IL (United States)

Sponsoring Organization:: Ministry of Education and Science of the Russian Federation; Russian Science Foundation; USDOE; USDOE Office of Science (SC), Basic Energy Sciences (BES) (SC-22). Materials Sciences & Engineering Division

Grant/Contract Number:: AC02-06CH11357

OSTI ID:: 1466378

Alternate ID(s):: OSTI ID: 1454280

Journal Information:: Nanoscale, Journal Name: Nanoscale Journal Issue: 24 Vol. 10; ISSN NANOHL; ISSN 2040-3364

Publisher:: Royal Society of ChemistryCopyright Statement

Country of Publication:: United States

Language:: English

References (53)

High-Moment Antiferromagnetic Nanoparticles with Tunable Magnetic Properties Hu, Wei; Wilson, Robert J.; Koh, AiLeen Advanced Materials, Vol. 20, Issue 8 https://doi.org/10.1002/adma.200703077	journal	April 2008
Nanoscale Materials for Tackling Brain Cancer: Recent Progress and Outlook Rozhkova, Elena A. Advanced Materials, Vol. 23, Issue 24 https://doi.org/10.1002/adma.201004714	journal	April 2011
X-Space MPI: Magnetic Nanoparticles for Safe Medical Imaging Goodwill, Patrick William; Saritas, Emine Ulku; Croft, Laura Rose Advanced Materials, Vol. 24, Issue 28 https://doi.org/10.1002/adma.201200221	journal	March 2012
Efficient Cisplatin Pro-Drug Delivery Visualized with Sub-100 nm Resolution: Interfacing Engineered Thermosensitive Magnetomicelles with a Living System Vitol, Elina A.; Rozhkova, Elena A.; Rose, Volker Advanced Materials Interfaces, Vol. 1, Issue 7 https://doi.org/10.1002/admi.201400182	journal	June 2014
Chemical Design of Nanoparticle Probes for High‐Performance Magnetic Resonance Imaging Jun, Young‐wook; Lee, Jae‐Hyun; Cheon, Jinwoo Angewandte Chemie International Edition, Vol. 47, Issue 28 https://doi.org/10.1002/anie.200701674	journal	June 2008
Nanomedicine-Challenge and Perspectives Riehemann, Kristina; Schneider, Stefan W.; Luger, Thomas A. Angewandte Chemie International Edition, Vol. 48, Issue 5 https://doi.org/10.1002/anie.200802585	journal	January 2009
Protein-Functionalized Synthetic Antiferromagnetic Nanoparticles for Biomolecule Detection and Magnetic Manipulation Fu, Aihua; Hu, Wei; Xu, Liang Angewandte Chemie International Edition, Vol. 48, Issue 9 https://doi.org/10.1002/anie.200803994	journal	January 2009
Rapid dry-reagent immunomagnetic biosensing platform based on volumetric detection of nanoparticles on 3D structures Orlov, Alexey V.; Bragina, Vera A.; Nikitin, Maxim P. Biosensors and Bioelectronics, Vol. 79 https://doi.org/10.1016/j.bios.2015.12.049	journal	May 2016
New type of biosensor based on magnetic nanoparticle detection Nikitin, Petr I.; Vetoshko, Petr M.; Ksenevich, Tatiana I. Journal of Magnetism and Magnetic Materials, Vol. 311, Issue 1 https://doi.org/10.1016/j.jmmm.2006.10.1180	journal	April 2007
Highly sensitive room-temperature method of non-invasive in vivo detection of magnetic nanoparticles Nikitin, Maxim P.; Vetoshko, Petr M.; Brusentsov, Nikolai A. Journal of Magnetism and Magnetic Materials, Vol. 321, Issue 10 https://doi.org/10.1016/j.jmmm.2009.02.108	journal	May 2009
Detection of fine magnetic particles coated on a thread using an HTS–SQUID Kawagishi, K.; Itozaki, H.; Kondo, T. Physica C: Superconductivity, Vol. 412-414 https://doi.org/10.1016/j.physc.2003.12.088	journal	October 2004
Magnetic Immunoassay for Detection of Staphylococcal Toxins in Complex Media Orlov, Alexey V.; Khodakova, Julia A.; Nikitin, Maxim P. Analytical Chemistry, Vol. 85, Issue 2 https://doi.org/10.1021/ac303075b	journal	December 2012
Energy Transfer with Semiconductor Quantum Dot Bioconjugates: A Versatile Platform for Biosensing, Energy Harvesting, and Other Developing Applications Hildebrandt, Niko; Spillmann, Christopher M.; Algar, W. Russ Chemical Reviews, Vol. 117, Issue 2 https://doi.org/10.1021/acs.chemrev.6b00030	journal	March 2016
Fast, Ratiometric FRET from Quantum Dot Conjugated Stabilized Single Chain Variable Fragments for Quantitative Botulinum Neurotoxin Sensing Lee, Joonseok; Brennan, Melissa B.; Wilton, Rosemarie Nano Letters, Vol. 15, Issue 10 https://doi.org/10.1021/acs.nanolett.5b03442	journal	September 2015
Induction of Calcium Influx in Cortical Neural Networks by Nanomagnetic Forces Tay, Andy; Kunze, Anja; Murray, Coleman ACS Nano, Vol. 10, Issue 2 https://doi.org/10.1021/acsnano.5b07118	journal	January 2016
Nanoscale Size Effect of Magnetic Nanocrystals and Their Utilization for Cancer Diagnosis via Magnetic Resonance Imaging Jun, Young-wook; Huh, Yong-Min; Choi, Jin-sil Journal of the American Chemical Society, Vol. 127, Issue 16 https://doi.org/10.1021/ja0422155	journal	April 2005
Stimuli-Responsive Magnetic Nanomicelles as Multifunctional Heat and Cargo Delivery Vehicles Kim, Dong-Hyun; Vitol, Elina A.; Liu, Jing Langmuir, Vol. 29, Issue 24 https://doi.org/10.1021/la3044158	journal	December 2012
Retro-orbital injections in mice Yardeni, Tal; Eckhaus, Michael; Morris, H. Douglas Lab Animal, Vol. 40, Issue 5 https://doi.org/10.1038/laban0511-155	journal	April 2011
Neural recording and modulation technologies Chen, Ritchie; Canales, Andres; Anikeeva, Polina Nature Reviews Materials, Vol. 2, Issue 2 https://doi.org/10.1038/natrevmats.2016.93	journal	January 2017
Tomographic imaging using the nonlinear response of magnetic particles Gleich, Bernhard; Weizenecker, Jürgen Nature, Vol. 435, Issue 7046 https://doi.org/10.1038/nature03808	journal	June 2005
Micro-engineered local field control for high-sensitivity multispectral MRI Zabow, Gary; Dodd, Stephen; Moreland, John Nature, Vol. 453, Issue 7198 https://doi.org/10.1038/nature07048	journal	June 2008
Shape-changing magnetic assemblies as high-sensitivity NMR-readable nanoprobes Zabow, G.; Dodd, S. J.; Koretsky, A. P. Nature, Vol. 520, Issue 7545 https://doi.org/10.1038/nature14294	journal	March 2015
Near-edge X-ray absorption fine-structure microscopy of organic and magnetic materials Ade, Harald; Stoll, Herman Nature Materials, Vol. 8, Issue 4 https://doi.org/10.1038/nmat2399	journal	April 2009
Biofunctionalized magnetic-vortex microdiscs for targeted cancer-cell destruction Kim, Dong-Hyun; Rozhkova, Elena A.; Ulasov, Ilya V. Nature Materials, Vol. 9, Issue 2 https://doi.org/10.1038/nmat2591	journal	November 2009
A magnetic switch for the control of cell death signalling in in vitro and in vivo systems Cho, Mi Hyeon; Lee, Eun Jung; Son, Mina Nature Materials, Vol. 11, Issue 12 https://doi.org/10.1038/nmat3430	journal	October 2012
Nanomagnetic actuation of receptor-mediated signal transduction Mannix, Robert J.; Kumar, Sanjay; Cassiola, Flávia Nature Nanotechnology, Vol. 3, Issue 1, p. 36-40 https://doi.org/10.1038/nnano.2007.418	journal	December 2007
Remote control of cellular behaviour with magnetic nanoparticles Dobson, Jon Nature Nanotechnology, Vol. 3, Issue 3 https://doi.org/10.1038/nnano.2008.39	journal	March 2008
Biocomputing based on particle disassembly Nikitin, Maxim P.; Shipunova, Victoria O.; Deyev, Sergey M. Nature Nanotechnology, Vol. 9, Issue 9 https://doi.org/10.1038/nnano.2014.156	journal	August 2014
Soliton-pair dynamics in patterned ferromagnetic ellipses Buchanan, Kristen S.; Roy, Pierre E.; Grimsditch, Marcos Nature Physics, Vol. 1, Issue 3 https://doi.org/10.1038/nphys173	journal	December 2005
Direct observation of imprinted antiferromagnetic vortex states in CoO/Fe/Ag(001) discs Wu, J.; Carlton, D.; Park, J. S. Nature Physics, Vol. 7, Issue 4 https://doi.org/10.1038/nphys1891	journal	January 2011
MPQ-cytometry: a magnetism-based method for quantification of nanoparticle–cell interactions Shipunova, V. O.; Nikitin, M. P.; Nikitin, P. I. Nanoscale, Vol. 8, Issue 25 https://doi.org/10.1039/C6NR03507H	journal	January 2016
Vortex state and effect of anisotropy in sub-100-nm magnetic nanodots Mejía-López, J.; Altbir, D.; Romero, A. H. Journal of Applied Physics, Vol. 100, Issue 10 https://doi.org/10.1063/1.2364599	journal	November 2006
Quantitative real-time in vivo detection of magnetic nanoparticles by their nonlinear magnetization Nikitin, M. P.; Torno, M.; Chen, H. Journal of Applied Physics, Vol. 103, Issue 7 https://doi.org/10.1063/1.2830947	journal	April 2008
Ferromagnetic microdisks as carriers for biomedical applications Rozhkova, E. A.; Novosad, V.; Kim, D. -H. Journal of Applied Physics, Vol. 105, Issue 7 https://doi.org/10.1063/1.3061685	journal	April 2009
An ultra-sensitive and wideband magnetometer based on a superconducting quantum interference device Storm, Jan-Hendrik; Hömmen, Peter; Drung, Dietmar Applied Physics Letters, Vol. 110, Issue 7 https://doi.org/10.1063/1.4976823	journal	February 2017
Applications of magnetic nanoparticles in biomedicine Pankhurst, Q. A.; Connolly, J.; Jones, S. K. Journal of Physics D: Applied Physics, Vol. 36, Issue 13 https://doi.org/10.1088/0022-3727/36/13/201	journal	June 2003
Progress in applications of magnetic nanoparticles in biomedicine Pankhurst, Q. A.; Thanh, N. T. K.; Jones, S. K. Journal of Physics D: Applied Physics, Vol. 42, Issue 22 https://doi.org/10.1088/0022-3727/42/22/224001	journal	November 2009
Development of a remanence measurement-based SQUID system with in-depth resolution for nanoparticle imaging Ge, Song; Shi, Xiangyang; Baker, James R. Physics in Medicine and Biology, Vol. 54, Issue 10 https://doi.org/10.1088/0031-9155/54/10/N01	journal	April 2009
Three-dimensional real-time in vivo magnetic particle imaging Weizenecker, J.; Gleich, B.; Rahmer, J. Physics in Medicine and Biology, Vol. 54, Issue 5 https://doi.org/10.1088/0031-9155/54/5/L01	journal	February 2009
The fabrication of uniform cylindrical nanoshells and their use as spectrally tunable MRI contrast agents Zabow, G.; Dodd, S. J.; Moreland, J. Nanotechnology, Vol. 20, Issue 38 https://doi.org/10.1088/0957-4484/20/38/385301	journal	August 2009
Magnetic vortex dynamics in the presence of pinning Compton, R. L.; Chen, T. Y.; Crowell, P. A. Physical Review B, Vol. 81, Issue 14 https://doi.org/10.1103/PhysRevB.81.144412	journal	April 2010
Deconvoluting reversal modes in exchange-biased nanodots Dumas, Randy K.; Li, Chang-Peng; Roshchin, Igor V. Physical Review B, Vol. 86, Issue 14 https://doi.org/10.1103/PhysRevB.86.144410	journal	October 2012
Vortex Chirality in Exchange-Biased Elliptical Magnetic Rings Jung, W.; Castaño, F. J.; Ross, C. A. Physical Review Letters, Vol. 97, Issue 24 https://doi.org/10.1103/PhysRevLett.97.247209	journal	December 2006
Nucleation and annihilation of magnetic vortices in sub-micron permalloy dots Novosad, V.; Guslienko, K. Yu.; Shima, H. IEEE Transactions on Magnetics, Vol. 37, Issue 4 https://doi.org/10.1109/20.951062	journal	July 2001
Advances in Giant Magnetoresistance Biosensors With Magnetic Nanoparticle Tags: Review and Outlook Wang, S. X. IEEE Transactions on Magnetics, Vol. 44, Issue 7 https://doi.org/10.1109/TMAG.2008.920962	journal	July 2008
Biomedical Nanomagnetics: A Spin Through Possibilities in Imaging, Diagnostics, and Therapy Krishnan, Kannan M. IEEE Transactions on Magnetics, Vol. 46, Issue 7 https://doi.org/10.1109/TMAG.2010.2046907	journal	July 2010
Multifunctional Ferromagnetic Disks for Modulating Cell Function Vitol, Elina A.; Novosad, Valentyn; Rozhkova, Elena A. IEEE Transactions on Magnetics, Vol. 48, Issue 11 https://doi.org/10.1109/TMAG.2012.2198209	journal	November 2012
Direct Observation of Internal Spin Structure of Magnetic Vortex Cores Wachowiak, A. Science, Vol. 298, Issue 5593 https://doi.org/10.1126/science.1075302	journal	October 2002
Magnetic Vortex Core Observation in Circular Dots of Permalloy Shinjo, T. Science, Vol. 289, Issue 5481 https://doi.org/10.1126/science.289.5481.930	journal	August 2000
Measurement of the vortex core in sub-100 nm Fe dots using polarized neutron scattering Roshchin, Igor V.; Li, Chang-Peng; Suhl, Harry EPL (Europhysics Letters), Vol. 86, Issue 6 https://doi.org/10.1209/0295-5075/86/67008	journal	June 2009
DNA Garden: A Simple Method for Producing Arrays of Stretchable DNA for Single-Molecule Fluorescence Imaging of DNA-Binding Proteins Igarashi, Chihiro; Murata, Agato; Itoh, Yuji Bulletin of the Chemical Society of Japan, Vol. 90, Issue 1 https://doi.org/10.1246/bcsj.20160298	journal	January 2017
Chemistry Can Make Strict and Fuzzy Controls for Bio-Systems: DNA Nanoarchitectonics and Cell-Macromolecular Nanoarchitectonics Komiyama, Makoto; Yoshimoto, Keitaro; Sisido, Masahiko Bulletin of the Chemical Society of Japan, Vol. 90, Issue 9 https://doi.org/10.1246/bcsj.20170156	journal	September 2017
Microfabricated magnetic structures for future medicine: from sensors to cell actuators Vitol, Elina A.; Novosad, Valentyn; Rozhkova, Elena A. Nanomedicine, Vol. 7, Issue 10 https://doi.org/10.2217/nnm.12.133	journal	October 2012

Cited By (6)

Data on characterization and validation of assays for ultrasensitive quantitative detection of small molecules: Determination of free thyroxine with magnetic and interferometric methods Orlov, A. V.; Znoyko, S. L.; Pushkarev, A. V. Data in Brief, Vol. 21 https://doi.org/10.1016/j.dib.2018.10.145	journal	December 2018
Magnetic-Assisted Treatment of Liver Fibrosis Levada, Kateryna; Omelyanchik, Alexander; Rodionova, Valeria Cells, Vol. 8, Issue 10 https://doi.org/10.3390/cells8101279	journal	October 2019
PCB-Based Magnetometer as a Platform for Quantification of Lateral-Flow Assays Khodadadi, Mohammad; Chang, Long; Trabuco, João R. C. Sensors, Vol. 19, Issue 24 https://doi.org/10.3390/s19245433	journal	December 2019
Nanoparticle-based drug delivery via RBC-hitchhiking for the inhibition of lung metastases growth Zelepukin, I. V.; Yaremenko, A. V.; Shipunova, V. O. Nanoscale, Vol. 11, Issue 4 https://doi.org/10.1039/c8nr07730d	journal	January 2019
Optical response of magnetically actuated biocompatible membranes Joisten, H.; Truong, A.; Ponomareva, S. Nanoscale, Vol. 11, Issue 22 https://doi.org/10.1039/c9nr00585d	journal	January 2019
Magnetometry based method for investigation of nanoparticle clearance from circulation in a liver perfusion model Zelepukin, I. V.; Yaremenko, A. V.; Petersen, E. V. Nanotechnology, Vol. 30, Issue 10 https://doi.org/10.1088/1361-6528/aafa3a	journal	January 2019

Figures / Tables (5)

Similar Records

Ferromagnetic particles as ultra-sensitive non-linear response labels for magnetic particles imaging (MPI) and sensing applications

Patent · Mon Jan 25 23:00:00 EST 2021 · OSTI ID:1805429

Ferromagnetic particles as ultra-sensitive non-linear response labels for magnetic particles imaging (MPI) and sensing applications

Patent · Tue Sep 12 00:00:00 EDT 2023 · OSTI ID:2222327

Related Subjects

in vitro
36 MATERIALS SCIENCE
in vivo
nanoparticle detection
nonlinear magnetic properties
patterned ferromagnets
retro-orbital administration
spin vortex state

Ultrasensitive detection enabled by nonlinear magnetization of nanomagnetic labels

Citation Formats

References (53)

Cited By (6)

Figures / Tables (5)

Similar Records

Related Subjects