Single-cell genomics for the masses
In this issue of Nature Biotechnology, Lan et al. describe a new tool in the toolkit for studying uncultivated microbial communities, enabling orders of magnitude higher single cell genome throughput than previous methods. This is achieved by a complex droplet microfluidics workflow encompassing steps from physical cell isolation through genome sequencing, producing tens of thousands of lowcoverage genomes from individual cells.
- Research Organization:
- Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
- Sponsoring Organization:
- SC-23.2 USDOE Office of Science (SC), Biological and Environmental Research (BER) (SC-23). Biological Systems Science Division
- Grant/Contract Number:
- AC02-05CH11231
- OSTI ID:
- 1439222
- Journal Information:
- Nature Biotechnology, Vol. 35, Issue 7; ISSN 1087-0156
- Publisher:
- Springer NatureCopyright Statement
- Country of Publication:
- United States
- Language:
- English
Cited by: 2 works
Citation information provided by
Web of Science
Web of Science
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