Improving on aquaporins

Siwy, Zuzanna; Fornasiero, Francesco

doi:10.1126/science.aao2440

Improving on aquaporins

Journal Article · Fri Aug 25 00:00:00 EDT 2017 · Science

DOI:https://doi.org/10.1126/science.aao2440· OSTI ID:1438767

Siwy, Zuzanna ^[1]; Fornasiero, Francesco ^[2]

Univ. of California, Irvine, CA (United States)
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

Biological nanopores can selectively and rapidly transport ions and molecules through membranes. For example, many biological ion channels conduct only one type of ion across the cell membrane, and they do so in response to external stimuli. Aquaporins transport water at astonishingly high rates and are efficient desalination units, in that they have excellent rejection of all ions, including protons. In conclusion, on page 792 of this issue, Tunuguntla et al. present an artificial nanopore system that sustains water fluxes exceeding those of aquaporins, exhibits ionic selectivities comparable to those of biological ion channels, and consists of carbon nanotubes (CNTs) that are 10 nm long and merely 0.8 nm in diameter embedded in a lipid bilayer.

Research Organization:: Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)

Sponsoring Organization:: USDOE

Grant/Contract Number:: AC52-07NA27344

OSTI ID:: 1438767

Report Number(s):: LLNL-JRNL--735736

Journal Information:: Science, Journal Name: Science Journal Issue: 6353 Vol. 357; ISSN 0036-8075

Publisher:: AAASCopyright Statement

Country of Publication:: United States

Language:: English

References (10)

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Cited By (6)

Correlated interfacial water transport and proton conductivity in perfluorosulfonic acid membranes Ling, Xiao; Bonn, Mischa; Domke, Katrin F. Proceedings of the National Academy of Sciences, Vol. 116, Issue 18 https://doi.org/10.1073/pnas.1817470116	journal	April 2019
Ultrafast selective transport of alkali metal ions in metal organic frameworks with subnanometer pores Zhang, Huacheng; Hou, Jue; Hu, Yaoxin Science Advances, Vol. 4, Issue 2 https://doi.org/10.1126/sciadv.aaq0066	journal	February 2018
Permselectivity limits of biomimetic desalination membranes Werber, Jay R.; Elimelech, Menachem Science Advances, Vol. 4, Issue 6 https://doi.org/10.1126/sciadv.aar8266	journal	June 2018
Dynamic Curvature Nanochannel‐Based Membrane with Anomalous Ionic Transport Behaviors and Reversible Rectification Switch Wang, Miao; Meng, Haiqiang; Wang, Dan Advanced Materials, Vol. 31, Issue 11 https://doi.org/10.1002/adma.201805130	journal	January 2019
Membrane Transport of Nonelectrolyte Solutions in Concentration Polarization Conditions: H r Form of the Kedem–Katchalsky–Peusner Equations Batko, Kornelia M.; Ślęzak, Andrzej International Journal of Chemical Engineering, Vol. 2019 https://doi.org/10.1155/2019/5629259	journal	April 2019
Effect of Enhanced Thermal Stability of Alumina Support Layer on Growth of Vertically Aligned Single-Walled Carbon Nanotubes and Their Application in Nanofiltration Membranes In, Jung Bin; Cho, Kang Rae; Tran, Tung Xuan Nanoscale Research Letters, Vol. 13, Issue 1 https://doi.org/10.1186/s11671-018-2585-3	journal	June 2018

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