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Title: Treatments and Preventative Measures for Trauma‐Induced Heterotopic Ossification: A Review

Journal Article · · Clinical and Translational Science
DOI:https://doi.org/10.1111/cts.12552· OSTI ID:1434810
 [1];  [2];  [2]
  1. Unites States Army Institute of Surgical Research Joint Base Fort Sam Houston Texas USA, University of North Texas Health Science Center Fort Worth Texas USA
  2. Unites States Army Institute of Surgical Research Joint Base Fort Sam Houston Texas USA

Sponsoring Organization:
USDOE
OSTI ID:
1434810
Alternate ID(s):
OSTI ID: 1434811
Journal Information:
Clinical and Translational Science, Journal Name: Clinical and Translational Science Vol. 11 Journal Issue: 4; ISSN 1752-8054
Publisher:
Wiley-BlackwellCopyright Statement
Country of Publication:
United Kingdom
Language:
English
Citation Metrics:
Cited by: 12 works
Citation information provided by
Web of Science

References (65)

Heterotopic Ossification After Surgery for Fractures and Fracture-Dislocations Involving the Proximal Aspect of the Radius or Ulna journal January 2013
Excision of Heterotopic Ossification from the Knee: A Functional Outcome Study journal January 2005
The suppression of heterotopic ossifications journal December 1998
Trauma-Induced Inflammation and Fracture Healing journal January 2010
Challenges in definitive fracture management of blast injuries journal June 2015
Effects of Nonsteroidal Anti-Inflammatory Drugs on Bone Formation and Soft-Tissue Healing journal January 2004
Heterotopic ossification prophylaxis with indomethacin increases the risk of long-bone nonunion journal July 2003
Biochemical Sequences in the Transformation of Normal Fibroblasts in Adolescent Rats journal June 1972
Ectopic bone formation in severely combat-injured orthopedic patients — A hematopoietic niche journal September 2013
Indomethacin Versus Radiation Therapy for Heterotopic Ossification After Hip Arthroplasty journal December 2001
Inhibition of Mammalian Target of Rapamycin Signaling with Rapamycin Prevents Trauma-Induced Heterotopic Ossification journal November 2017
Combat Versus Civilian Open Tibia Fractures: The Effect of Blast Mechanism on Limb Salvage journal January 2011
Operative Treatment of Heterotopic Hip Ossification in Patients With Coma After Brain Injury journal January 1999
Characterizing the Acute Phase Response in Healthy Patients Following Total Joint Arthroplasty: Predictable and Consistent journal January 2017
Resection of elbow ossification and continuous passive motion in postcomatose patients journal May 1999
Functional Outcome Following Surgical Excision of Heterotopic Ossification in Patients with Traumatic Brain Injury journal January 1993
Wnt signaling in bone formation and its therapeutic potential for bone diseases journal January 2013
Prostaglandins and bone: physiology and pathophysiology journal July 1999
Trauma-induced heterotopic bone formation and the role of the immune system: A review journal January 2016
Systemic inflammation after trauma journal December 2007
A Novel Role for the BMP Antagonist Noggin in Sensitizing Cells to Non-canonical Wnt-5a/Ror2/Disheveled Pathway Activation journal May 2017
Heterotopic ossification: a systematic review journal July 2014
Prophylaxis of heterotopic ossification – an updated review journal April 2009
The traumatic bone: trauma-induced heterotopic ossification journal August 2017
Inhibition of Heterotopic Ossification With Radiation Therapy in an Animal Model journal January 1998
The Genetics of Heterotopic Ossification: Insight Into the Bone Remodeling Pathway journal January 2010
Inflammation, fracture and bone repair journal May 2016
The Experimental Production of Ectopic Cartilage and bone in the Muscles of Rabbits journal January 1949
Treatment of heterotopic ossification of the elbow following burn injury: Recommendations for surgical excision and perioperative prophylaxis using radiation therapy journal December 2010
Heterotopic Ossification in Complex Orthopaedic Combat Wounds: Quantification and Characterization of Osteogenic Precursor Cell Activity in Traumatized Muscle journal January 2011
Heterotopic Ossification Following Traumatic and Combat-Related Amputations: Prevalence, Risk Factors, and Preliminary Results of Excision journal January 2007
What Risk Factors Predict Recurrence of Heterotopic Ossification After Excision in Combat-related Amputations? journal January 2015
Reactions of Thigh Tissues of Sheep to Blunt Trauma journal June 1983
Effect of short-course indomethacin on heterotopic bone formation after uncemented total hip arthroplasty journal September 1991
Inflammatory Cytokine and Chemokine Expression is Associated With Heterotopic Ossification in High-Energy Penetrating War Injuries journal January 2012
Heterotopic Ossification in Orthopaedic Trauma journal January 2012
Gluteus minimus necrotic muscle debridement diminishes heterotopic ossification after acetabular fracture fixation journal November 2002
Defining the Balance between Regeneration and Pathological Ossification in Skeletal Muscle Following Traumatic Injury journal April 2017
Heterotopic Ossification in Civilians With Lower Limb Amputations journal September 2014
Optimal Timing of Preoperative Radiation for Prophylaxis Against Heterotopic Ossification: A Rabbit Hip Model journal January 2005
The effect of diphosphonates on heterotopic ossification in regenerating achilles tendon of the mouse journal April 1983
Bone: Formation by Autoinduction journal November 1965
Risk Factors for the Development of Heterotopic Ossification After Knee Dislocation journal July 2014
Excision of heterotopic ossification around the knee following brain injury journal March 1996
Blast injuries and heterotopic ossification journal August 2012
Cost of Radiotherapy Versus NSAID Administration for Prevention of Heterotopic Ossification After Total Hip Arthroplasty journal August 2008
Heterotopic Ossification Following Combat-Related Trauma
  • Potter, MAJ Benjamin K.; Forsberg, LCDR Jonathan A.; Davis, Thomas A.
  • The Journal of Bone and Joint Surgery-American Volume, Vol. 92, Issue Suppl 2 https://doi.org/10.2106/JBJS.J.00776
journal January 2010
Risk Factors for the Development of Heterotopic Ossification After Acetabular Fracture Fixation journal June 2014
Prevention of heterotopic ossification in high-risk patients with total hip arthroplasty: the experience of a combined therapeutic protocol journal February 2006
Targeted stimulation of retinoic acid receptor-γ mitigates the formation of heterotopic ossification in an established blast-related traumatic injury model journal September 2016
Prostaglandins and Inflammation journal May 2011
Excision for the Treatment of Periarticular Ossification of the Knee in Patients Who Have a Traumatic Brain Injury* journal January 1999
Heterotopic Ossification in Trauma journal January 2017
Palovarotene inhibits connective tissue progenitor cell proliferation in a rat model of combat-related heterotopic ossification: PALOVAROTENE INHIBITS PROGENITOR CELL PROLIFERATION journal November 2017
Heterotopic Ossification After Extremity Blast Amputation in a Sprague-Dawley Rat Animal Model journal January 2011
A Clinical Perspective on Common Forms of Acquired Heterotopic Ossification journal February 1991
Burn Injury Enhances Bone Formation in Heterotopic Ossification Model journal January 2014
Incidence of Heterotopic Ossification in Patients Receiving Radiation Therapy following Total Hip Arthroplasty journal January 2014
The development of a rat model to investigate the formation of blast-related post-traumatic heterotopic ossification journal April 2015
Heterotopic ossification of the shoulder in patients with traumatic brain injury journal January 2013
Functional Outcome Following Surgical Resection of Heterotopic Ossification in Patients with Brain Injury journal January 1996
Myositis ossificans following forcible manipulation of the leg. A rabbit model for the study of heterotopic bone formation. journal January 1980
Locally Delivered Nonsteroidal Antiinflammatory Drug: A Potential Option for Heterotopic Ossification Prevention: Local NSAIDs for Heterotopic Ossification journal June 2015
Impact of the Operative Delay and the Degree of Neurologic Sequelae on Recurrence of Excised Heterotopic Ossification in Patients With Traumatic Brain Injury journal January 2012
Early local delivery of vancomycin suppresses ectopic bone formation in a rat model of trauma-induced heterotopic ossification: VANCOMYCIN SUPPRESSES TRAUMA-INDUCED HO journal April 2017

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